Principal Scientist I, Drug Discovery - Cambridge, United States - Novartis

Novartis

Verified Company

Cambridge, United States

1 week ago

Posted by:

Mark Lane

beBee recruiter

Description

Summary:

Internal Job Title:
Principal Scientist I

Role Location:

Cambridge, MA, onsite About the role: We are seeking a motivated scientist with expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease.

In this role, you will be responsible for driving research program(s) focused on delineating the key mechanisms involved in proteinuric kidney diseases and progressing new targets towards drug discovery.

This individual will join the Renal Research team within Disease Area X (DAx) in Biomedical Research and report to the Head of Renal Research.

About the Role:

Internal Job Title:
Principal Scientist I

Role Location:
Cambridge, MA, onsite

About the role:

We are seeking a motivated scientist with expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease.

This individual will join the Renal Research team within Disease Area X (DAx) in Biomedical Research and report to the Head of Renal Research.

Key Responsibilities:

Contribute to the Biomedical Research drug discovery process with the goal of progressing the development of new therapeutic options for patients with chronic kidney diseases.
Formulate novel target hypothesis based on human disease mechanisms using deep and broad scientific expertise in renal physiology and pathophysiology of proteinuric kidney diseases.
Design and execute in vitro and in vivo research plans to interrogate target biology and progress drug discovery for novel targets across multiple therapeutic modalities.
Enable partnerships with data scientists, external partners, and individuals across Biomedical Research Disease Areas and platform functions.
Develop and communicate project strategy, scientific vision, and data to key stakeholders.

Essential Requirements:

A PhD and/or MD degree with postdoctoral experience and a minimum of two years of research in renal biology and physiology, preferably in the pharmaceutical or biotechnology industry.
Indepth knowledge of kidney (patho)physiology, including cultivation and analysis of complex renal cellbased platforms.
Indepth knowledge of kidney (patho)physiology, including cultivation and analysis of complex renal cellbased platforms, e.g. 3D kidney organoids, primary 2D/3D endothelial or epithelial cell systems.
Extensive "handson" experience and proven trackrecord in the use of a wide range of cellular, biochemical and genome editing methods and technologies to unravel complex cellular signaling pathways
Experience in using multiomics and/or patient data for target and pathway identification.
A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts.
Excellent oral and written communication skills (in English) are essential.
Team orientated and collaborative work ethic.
Demonstrated ability to coach and empower others including development of early career scientists.

Commitment
to
Diversity
and
Inclusion / EEO:The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary:

The pay range for this position at commencement of employment is expected to be between $112,800 to $169,200/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period.

Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities.

The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered.

Details of participation in these benefit plans will be provided if