Director of Translational Medicine - Waltham, United States - Deciphera Pharmaceuticals

Deciphera Pharmaceuticals

Verified Company

Waltham, United States

3 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

Company Description

Deciphera is a biopharmaceutical company focused on discovering, developing and commercializing important new medicines to improve the lives of people with cancer.

We are leveraging our proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines.

See here for more details on our portfolio.

This position will be located in Waltham, MA and will report to the Executive Director, Translational Medicine located in the Waltham, MA office.

Key Responsibilities:

Reporting to Executive Director, Translational Medicine, this role will drive translational medicine strategy across multiple earlystage programs.
Develop and implement scientificallydriven yet practical clinical biomarker plan to address key programlevel questions in alignment with crossfunctional team.
Direct or indirect involvement as Translational Medicine lead for multiple programs and studies.
Provide oversight of assay development and validation activities of multiple CROs from a technical, budget and timeline perspective.
Represent Translational Medicine on crossfunctional teams and make strategic contributions to the clinical development plan.
Provide mentoring and support for direct reports.
Oversee biomarker data collection, analysis and interpretation for various presentations and publications.
Contribute to authoring/review of clinical study protocols, investigator brochures and additional documents as needed.
Responsible for budget and timeline across multiple studies/programs.
Establish effective communication with crossfunctional colleagues including those from medical, clinical pharmacology, preclinical biology and biometrics.
Commitment to help the team achieve deliverables and meet aggressive timelines.

Qualifications

PhD in Cancer Biology, Molecular Biology, Cellular Biology or related field
Over 10 years in the BioPharma industry, with at least 5 years in Translational Sciences or Translational Medicine working on clinical biomarkers.
Experience in oncology is a must, ideally in both solid tumor and hematologic oncology.
Involvement in both early and late state clinical trials.
Prior management of contract research organizations (CROs) for clinical biomarker assay development and qualification.
Strong biomarker data analysis experience including experience working with Biostatisticians, Programmers, Bioinformaticians and data visualization software is strongly preferred.
Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRTPCR, NGS and RNA Seq.
Prior experience implementing precision medicine approaches in clinical trials including companion diagnostic (CDx) development experience in liquidbased and tumor tissuebased approaches.
Strong communication and interpersonal skills and ability to build collaborative relationships in a crossfunctional environment is a must.
Strong leadership and strategic thinking skills.
Prior management experience.

Additional Information

We are proud to be Great Place to Work Certified 2023 and rank #25 on Fortune's Best Places to Work Small and Midsized Biotech Companies in 2023.

Find more details about our award-winning culture here.

We offer an outstanding culture and opportunity for personal and professional growth based on our "PATHS" Core Values:

Patients
We are committed to improving the lives of patients living with cancer. They are the driving force behind everything we do.

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Accountability

We demand accountability for our actions, behaviors, and performance. We recognize our duty to maintain a culture that embraces the uniqueness of our people and finds strength in our differences.

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Transparency

We strive to provide full visibility to internal and external stakeholders for a complete picture of what we are doing and why.

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Honesty and Integrity

Trust and mutual respect are essential aspects of our culture. We act with honesty and integrity in all facets of our business, and this serves as the foundation of our work and interactions with others.

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Stewardship

We are respectful of the resources entrusted to us by the investment community. We act thoughtfully and allocate resources responsibly in seeking to create value for our shareholders.

"How" we work together and the behaviors that we show up with each day are critical to maintaining our positive culture.

Our behavioral expectations align with our values to elevate and drive individual and team performance:

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Lead from where you are - regardless of role or level, we motivate each other to achieve common goals.
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Drive business results - we navigate forward with our eye on the highest priorities.
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Partner and collaborate - we cultivate relationships and value ideas, regardless of where they are coming from, to achieve more together.
- ** Continuously evolve