Jobs

    Principal Scientist, Protein Engineering - California, United States - Mirador Therapeutics, Inc.

    Mirador Therapeutics, Inc.
    Mirador Therapeutics, Inc. California, United States

    3 weeks ago

    Default job background
    Full time
    Description

    (San Diego, CA)

    Mirador is a next-generation precision medicine company focused on immunology and inflammation. The company's Mirador360 TM precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases. Launched in 2024, Mirador has raised over $400 million from leading life sciences investors and is based in San Diego, CA.

    Summary

    We are seeking a highly motivated protein engineer to join the biotherapeutics discovery group. The candidate must have demonstrable experience with antibody discovery and protein engineering programs in a biologics discovery setting.

    Responsibilities

  • Expertise in protein and antibody engineering in the discovery and preclinical development of biotherapeutic candidates. Assist in evaluating new technologies to stay at the cutting edge of biologics discovery, production, and characterization.
  • Play a key role in assessing protein structure and function as applied toward the evaluation of biologics for protein design and engineering.
  • Present your findings and ideas to an interdisciplinary team with a wide range of technical backgrounds.

    Qualifications
  • PhD in Molecular Biology, Structural Biology, Biophysics, Biochemistry, or related disciplines and 8 years or more of experience in the biotechnology or pharmaceutical industry
  • Manage all aspects of protein and antibody expression, purification, and characterization to support the preclinical discovery and development efforts of the biotherapeutics group.
  • Experience managing external CROs and vendors for protein engineering work.
  • Demonstrable experience in antibody discovery, antibody engineering, or the engineering of other proteins.
  • Familiarity with various antibody formats and scaffolds including, but not limited to fusion proteins, bi-specific antibodies, single-domain antibodies (VHH), and bi-paratopic antibodies.
  • Experience in mammalian cell culture and protein expression systems.
  • Self-starter, strong collaborative skills working in cross-functional teams and a start-up environment.

    The expected base pay range for this position is $150,000 – $225,000 plus bonus, equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. This range may be modified in the future.
    All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status or other protected class.
    Apply


  • Kelly Science, Engineering, Technology & Telecom California, United States

    Position Title: Protein Sciences Consultant - Biotechnology (Temporary-to-Hire) · Company: Leading Early Stage Biotechnology Company · Location: San Francisco Bay Area · Overview · We're seeking a dynamic and experienced Director of Research and Development to build and lead our ...


  • Wellington Executive Search California, United States

    Our client is an internationally based producer of functional plant-based proteins. We are looking to hire a Sales Professional with a food science and chemistry mindset, excellent interpersonal skills, can travel to meet with customers and put on technical presentations, and enj ...


  • Firefly Bio California, United States

    About Firefly Bio: · Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. Our state-of-the-art platform results in highly specific delivery of degraders to target tissue. Our mission is to realize ...


  • Storm3 California, United States

    ‍ Senior/Staff Software Engineer · AI Drug Discovery Unicorn ($1b+ valuation, at Series B) · San Francisco Bay Area, US (Hybrid) · $230,000 - $300,000 base + equity · This $1b+ valued Unicorn start-up is truly a leader in deep learning & generative AI, merging cutting-edge mod ...


  • Alldus California, United States

    Company Overview · Biotech company · Created a platform that uses computational approaches to identify proteins · Discovering and developing therapeutics for rare and chronic diseases · Partner with Pharma companies to develop therapeutics · Their technology is allowing clinical ...


  • SPT Labtech California, United States

    SPT Labtech has an exciting opportunity for a Territory Sales Manager to join our team. You'll be based in and covering the Southern California region and have overall responsibility and oversight for the sales success of our product range working alongside our talented commercia ...


  • Firefly Bio California, United States

    About Firefly Bio: · Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. Our state-of-the-art platform results in highly specific delivery of degraders to target tissue. Our mission is to realize ...


  • Theery California, United States

    We are developing transformative test products that enable early disease detection and treatment through game-changing advances in proteomic and metabolomic methods, as well as cutting edge next generation sequencing (NGS) technologies. As a member of the multi-disciplinary scien ...


  • Amber Bio California, United States

    Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a fir ...


  • Bayside Solutions California, United States

    Senior Research Associate, Discovery Biology · W2 Contract · Salary Range: $104,000 - $114,400 per year · Location: Redwood City, CA - Onsite Role · Job Summary: · As a Senior Research Associate, you will join a high-functioning team of chemical biologists, biochemists, and cell ...