Research Scientist - Rockville, United States - Axle

Axle
Axle
Verified Company
Rockville, United States

1 week ago

Mark Lane

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Mark Lane

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Description
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Axle is seeking a
_Research Scientist _to join our vibrant team at the National Institutes of Health (NIH) supporting the
National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.

Benefits We Offer:


  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Overall Position Summary and Objectives This task order will independently provide support services to satisfy the overall operational objectives of NCATS ETB.


Deliverables:


  • Work products and documents related to designing, synthesizing and optimizing chemical probes for potency and solubility; devise synthetic routes to target molecules; produce desired chemical libraries.
  • Ad-Hoc
  • Work products and documents related to carrying out scaleup of the chemical probes develop and produce chemical probers with linkers for conjugation to fluorescent reporters and other reporter groups.
  • Ad-Hoc
  • Work products and documents related to producing research reports; conduct and write literature reviews; search chemical databases for journal articles, patents and related technologies; publish and present relevant projects.
  • Ad-Hoc
  • Work products and documents related to coordinating projects being developed by external collaborators, proposing SAR strategies and monitoring their progress.
  • Ad-Hoc
  • Work products and documents related to collaboration with the technology transfer office and external patent offices to provide the necessary information for filing patents in selected programs.
  • Ad-Hoc

Work Details:


  • Advance the science through proposing and investigating new target projects for initiation based on novelty and relevance to human health

2:


  • Work with staff on assay design and method development using an array or experimentation

3:


  • Write technical reports and prepare manuscripts

4:


  • Prepare oral presentations and posters for internal and external groups/conferences

5:


  • Supports the planning and execution of research experiments in the context of the laboratory's overall research program.
  • Evaluate new techniques, instruments, and software for potential incorporation into current SOP.
  • Supports laboratory staff on research projects and techniques.
  • Work with staff on the interpretation of experiments performed by research scientists.
  • Work with postdoc/biological scientists to perform statistical analysis for research projects.
  • Maintains laboratory equipment and the training of others in their use.
  • Train staff on the proper usage of laboratory instruments and equipment.
  • Calibrate, maintain and troubleshoot instruments and equipment in the laboratory.
  • Operate, troubleshoot and train others to use laboratory equipment and software.
  • Provide advice and assistance to users in designing experiments, using instrumentation, data acquisition and analysis, and preparing figures for publication.
  • Assists in maintaining adequate space and facilities for ongoing and projected research studies.
  • Manage scientific equipment and resources (e.g. reagents, stocks of frozen sells, animal samples) including acquisition, documentation and storage.
  • Evaluates, analyzes and interprets research data, communicates results and methods in reports, presentations, and manuscripts.
  • Oversee project data quality; analyze and interpret project data.
  • Conduct bioinformatics data analyses and statistical analyses; prepare data for abstracts and manuscripts.
  • Maintain a detailed and uptodate electronic laboratory notebook detailing all experiments.
  • Coordinates with junior staff to modify research protocols.
  • Work with staff to confirm assay results and evaluate new techniques and instruments; search literature; propose, design and test alternative assays for difficult screening targets; confirm assay results; develop secondary assays.
  • Coordinate projects being developed in the laboratory, proposing SAR strategies and monitoring their progress.
  • Coordinate with IT staff on all software issues specific to the chemistry group and on all computer problems.
  • Participate in establishing criteria and standards for others to follow in the planning, review and evaluation of bioinformatics research projects.
  • Suggest alternative or complementary approaches to experiments.
  • Presents research at national scientific meetings and symposia.
  • Coauthor manuscripts on research projects; publish in peerreviewed journals.
  • Write papers and abstracts detailing research efforts and results for publication in peerreviewed journals; prepare PowerPoint presentations as appropriate.
  • Give posters and presentations detailing work at regional and national scientific meetings.
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