Scientist, Peptide Chem - San Diego, United States - Neurocrine Bioscience

Mark Lane

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Mark Lane

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Description

Who We Are:


At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values.

We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.


What We Do:


Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options.

We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders.

The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas.

For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions.

We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. _*in collaboration with AbbVie_


About the Role:
Work on the design, synthesis and characterization of novel peptides to discover next-generation peptide-based therapeutics. Use expert synthetic knowledge and proven design and synthetic accomplishments to enable progress in peptide-related drug discovery.

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Your Contributions (include, but are not limited to):

  • Synthesis, purification and characterization of peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, purification, analytical and biophysical techniques-
  • Independent data-driven optimization of peptide SAR
  • Aid in lab setup, instrument purchase, installation and ongoing lab operations
  • Effective communication of scientific rationale, results and interpretation at project, team and departmental meetings, contributing to strategic discussions
  • Active collaboration and sharing of expertise with colleagues
  • Performs other job related duties as assigned

Requirements:


  • BS/BA degree in chemistry or closely related field and 10+ years' experience in peptide OR synthesis, purification, and characterization, a proven track record in peptide technologies and hit discovery, strong knowledge in peptide chemistry and medicinal chemistry, experience in complex synthetic strategies and modern peptide chemistry techniques, proficiency in using analytical instruments
  • MS/MA degree in chemistry or closely related field and 8+ years of similar experience as noted above OR
  • PhD in organic chemistry, or related field, with 03 subsequent years of experience in the field
  • Proficient in all aspects of modern peptide synthesis, purification and analysis; capable of immediate independent laboratory work on solid

- and solution-phase chemistry
  • Strong publication record of accomplishment
  • Strong understanding of peptide structure and associated biophysical techniques to assess peptide structure, stability and behavior in solution
  • Experience in bioconjugation and timeextension strategies for peptides
  • Excellent interpersonal skills with strong oral and written communication abilities#LI-AD1
Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

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The annual base salary we reasonably expect to pay is $86,200.00-$125, Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills.

In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program.

Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.


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