- Doctorate degree (PhD, ScD and/or MD) in computational biology, statistical genetics, quantitative genomics, bioinformatics or relevant area
- Analytical experience with single-cell RNA-seq, single-cell multi-omics and other NGS-based seq
- Fluency in R/Python/TensorFlow analytic techniques necessary for data analysis
- Experience working with cloud computing environment and data management
- Publication track record in peer-review journals
- Experience in biomedical studies relevant to diseases being investigated including musculoskeletal diseases
- Strong interpersonal, collaborative, organizational, and presentation (oral or written) skills
-
Research Fellow
2 days ago
Biogen Cambridge, United States**Job Description** Job Description** · **What You'll Do** · - Your main focus will be to design synthetic routes and utilize state of the art organic chemistry to enable the synthesis of targets to be tested against a neurodegenerative disease. · - You will have the opportunity ...
-
Postdoctoral Research Fellow
1 day ago
Northeastern University Boston, United StatesAbout the Opportunity · Northeastern University is looking for a postdoctoral research fellow in artificial intelligence (AI) and machine learning (ML) as well as network science (NS) and optimization (NO) for threat deterrence, risk assessment, and resource allocation in the bro ...
-
Research Fellow, Pgy0
6 days ago
Mass. Eye and Ear (MEE) Boston, United States**Research Fellow, PGY0 - Meniere's disease** · ***: · We study the underlying causes of vestibular disorders, specifically Meniere's disease, on the molecular level, using whole genome sequencing in clinical patients, histological and molecular analysis of human pathology specim ...
-
Research Fellow, Pediatric Newborn Medicine
15 hours ago
Brigham & Women's Hospital(BWH) Boston, United States**Research Fellow, Pediatric Newborn Medicine** · **Brigham and Women's Hospital, Beth Israel Deaconess Hospital, Harvard Medical School.** · **EEO Statement** · **Primary Location** MA-Boston-BWH Boston Main Campus · **Work Locations** BWH Boston Main Campus 75 Francis St Boston ...
-
Research Fellow, School of Public Health
15 hours ago
Boston University Boston, United States**Summary**:The Department of Global Health at the Boston University School of Public Health has an opening for a masters graduate or pre-doctoral fellow to perform **quantitative data analysis** for research projects on the economics and epidemiology of HIV in sub-Saharan Africa ...
-
Research Fellow
1 week ago
Spaulding Rehabilitation Boston, United StatesResearch Fellow · **Description** · PhD Postdoctoral Machine Learning in Healthcare Fellow · Wanted: · Outstanding PhD for postdoctoral machine learning fellowship at the Cardiovascular Imaging Research Center ) at Massachusetts General Hospital and Harvard Medical School. · The ...
-
Research Fellow
1 week ago
Mass General Physicians Organization(MGPO) Boston, United StatesGENERAL SUMMARY · The McCance Center for Brain Health in the Department of Neurology at Mass General Hospital is looking for a highly motivated individual with a background in social and behavioral sciences and/or public health to perform cutting-edge research utilizing quantitat ...
-
Research Fellow
1 week ago
Mass General Physicians Organization(MGPO) Boston, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: · The Massachusetts General Hospital ICU Precision Medicine Lab, as part of the MGH Clinical Data Center and the National Patient-Centered CHoRUS for Equitable AI Collaboration, is seeking a Postdoctoral Fellow to participate in ongoing resear ...
-
Research Fellow
1 week ago
Mass General Physicians Organization(MGPO) Boston, United StatesIn the research area of materials for drug and gene delivery, the Center for Systems Biology (CSB) at Massachusetts General Hospital (MGH) seeks applications for postdoctoral fellows interested in new methods for gene and drug delivery. Areas of interest include ultrasound, nanom ...
-
Research Fellow
6 days ago
Mass General Physicians Organization(MGPO) Boston, United StatesPhD Postdoctoral Machine Learning in Healthcare Fellow · Wanted: · Outstanding PhD for postdoctoral machine learning fellowship at the Cardiovascular Imaging Research Center ) at Massachusetts General Hospital and Harvard Medical School. · The fellow will lead deep learning proj ...
-
Research Fellow
1 week ago
Mass General Physicians Organization(MGPO) Boston, United StatesThe Yonker Laboratory in the Mucosal and Immunology and Biology Research Center (MIBRC) at Massachusetts General Hospital and Harvard Medical School is seeking a highly motivated postdoctoral research fellow. · The Yonker Lab works from bench to bedside to define innate immune ac ...
-
Research Fellow
1 week ago
Biogen Idec Cambridge, United StatesCompany DescriptionJob Description · Job Description · Biogen is one of the world's leading biopharmaceutical companies, with a focus on developing therapies for serious conditions in neurology, immunology, and rare diseases. We are committed to research that uncovers the underly ...
-
Research Fellow
1 week ago
Biogen Cambridge, United StatesCompany Description · Job Description · Job Description · Biogen is one of the world's leading biopharmaceutical companies, with a focus on developing therapies for serious conditions in neurology, immunology, and rare diseases. We are committed to research that uncovers the unde ...
-
Postdoctoral Research Fellow
1 week ago
Brigham and Women's Hospital Brookline, United StatesThe Division of Preventive Medicine in the Department of Medicine at the Brigham and Women's Hospital invites applications for a full-time Postdoctoral Research Fellow with expertise in biostatistics, applied machine learning, multi-omics, and epidemiologic cohort analyses. Addit ...
-
Research Fellow
1 week ago
Harvard University Cambridge, United StatesDetails · Title Research Fellow · School Harvard School of Dental Medicine · Department/Area Kota Lab/Department of Oral Medicine, Infection, and Immunity · Position Description · Kota Laboratory at Harvard School of Dental Medicine is seeking a postdoctoral candidate to stu ...
-
Research Fellow
1 week ago
Massachusetts General Hospital Boston, United States Full timeResearch Fellow Description Research Fellow in Molecular Biology with a Focus on Aging and Metabolism · Job Summary: · The Manstein Laboratory at Massachusetts General Hospital is conducting research in dermatology, focusing on the development of novel, energy-based procedure ...
-
Research Fellow
1 week ago
Harvard Pilgrim HealthCare Boston, United States Full timeWho We Are · Point32Health is a leading health and wellbeing organization, delivering an ever-better personalized health care experience to everyone in our communities. At Point32Health, we are building on the quality, nonprofit heritage of our founding organizations, Tufts Healt ...
-
Research Fellow
5 days ago
Harvard Pilgrim HealthCare Boston, United States Full timeWho We Are · Point32Health is a leading health and wellbeing organization, delivering an ever-better personalized health care experience to everyone in our communities. At Point32Health, we are building on the quality, nonprofit heritage of our founding organizations, Tufts Healt ...
-
Research Fellow
15 hours ago
Biogen Cambridge, United StatesJob Description · Job DescriptionJob Description · About This Role · The computational science group at Biogen is seeking a creative and self-motivated research fellow to design, develop, and apply new machine learning algorithms for the discovery of novel AAV capsids. The Resea ...
-
Postdoctoral Research Fellow
1 week ago
Beth Israel Lahey Health Brookline, United StatesWhen you join the growing BILH team, you're not just taking a job, you're making a difference in people's lives. · Job Type: · Regular · Scheduled Hours: · 40 · Work Shift: · Day (United States of America) · Has been awarded or has completed the requirements for a doctoral degree ...
Post-Doctoral Research Fellow - Roslindale, United States - Hebrew SeniorLife
Description
The Marcus Institute for Aging Research is actively seeking a highly qualified and motivated Post-Doctoral Research Fellow and computational biologist with a strong background in NGS-based RNA-seq at single-cell resolution as well as 10X-based single-cell multi-omics data analyses and NGS-based analytical pipelines with innovative statistical and deep-learning modeling to explain skeletal biological mechanisms underlying the observation that the response to drug therapy for osteoporosis wears off over time. The post-doc will join a Bioinformatics Core recently established via a NIH P50 Center Grant with joint effort from Harvard Medical School, Harvard Dental School, Massachusetts General Hospital, Beth Israel Deaconess Medical Center and the Marcus Institute for Aging Research, Boston, MA.
Bone biopsies from treated patients will be collected before and after treatment of osteoporosis in women who are being seen for osteoporosis at the Massachusetts General Hospital. 10X single-cell multi-omics seq, single-cell and bulk RNA-seq, and proteomics will be measured from both blood and bone biopsy samples. In addition, mice treated with the same drugs as in the clinical trials will also be conducted and bone biopsies will be collected at different time points during treatment. The same set of single-cell measurements will be conducted in bone samples collected from treated mice. Cross-species comparison analysis will also be conducted. The successful candidate will have a track record of innovative and collaborative research demonstrated through a strong training program and peer-reviewed publications.
In this vital role, the post-doc will develop and carry out analytical plans and statistical/bioinformatic analyses to study the effects of osteoporosis anabolic therapies on osteoblast progenitors as well as osteocytes in clinical and pre-clinical studies. Computational analysis on single-cell RNA-seq, bulk RNA-seq and multi-omics seq obtained from post-menopausal women and female mice treated with osteoporosis anabolic therapies (either sclerostin inhibitor or PTH) will be analyzed. Additional bioinformatic analyses will be conducted to prioritize genes regulating bone formation via existing human genetic variation association analyses; and proposed knockout mice with deeply skeletal phenotypes from collaborators. The post-doc will interact with skeletal biologists, clinicians, computational biologists, statistical geneticists, and bench scientists at Harvard Medical School, Harvard Dental School, Massachusetts General Hospital, Beth Israel Deaconess Medical Center, the Marcus Institute for Aging Research Boston University and the Broad Institute of MIT and Harvard. An ability to communicate clearly and collaborate effectively with colleagues from different disciplines will be essential.
&v=024){kind=logo}
