- Lead efforts to evaluate ADC targets with the goal of producing viable therapeutic interventions, including target prioritization and evaluation of linkers and payloads
- Oversee studies aimed at generating datasets to inform machine learning models of tumor ADC sensitivity
- Lead preclinical validation of prioritized ADC antibody-linker-warhead combinations in cells and tumor models
- Collaborate with external acceleration partners in efforts related to insitro's ADC program
- Provide ADC biology expertise including strategic, scientific and technical mentorship to shape insitro's ADC portfolio
- PhD in a biological science related field (Cell bio, Biochem, Genetics etc.) with 8+ years of industry experience including 5+ years in ADC target or therapeutic discovery and/or development
- Understanding of ADC components, construction and mechanisms of action
- Record of leading project teams
- Experience managing CROs and collaborating with external partners
- Experience working with data scientists / computational biologists /statistical geneticists
- 401(k) plan with employer matching for contributions
- Excellent medical, dental, and vision coverage (insitro pays 100% of premiums for employees on our base plans), as well as mental health and well-being support
- Open, flexible vacation policy
- Paid parental leave
- Quarterly budget for books and online courses for self-development
- Support to occasionally attend professional conferences that are meaningful to your career growth and development
- New hire stipend for home office setup
- Monthly cell phone & internet stipend
- Access to free onsite baristas and cafe with daily lunch and breakfast
- Access to free onsite fitness center
- Commuter benefits
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Medical Director, Clinical Oncology
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Regional Sales Director, Oncology
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Invitae San Francisco, United StatesTerritory: U.S. Eastern Region. · The ideal person resides in the region. · This is a field sales leadership role and will require extensive travel and some work during the evenings and occasional weekends. · This role is eligible for an annual, uncapped Incentive Compensation of ...
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AbbVie, Inc San Francisco, United StatesCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas ...
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AbbVie San Francisco, United StatesJob Description · Job DescriptionCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives acr ...
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Director, Oncology Research
1 week ago
BioSpace South San Francisco, United StatesJob Details · HOW MIGHT YOU DEFY IMAGINATION? · If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global col ...
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Director, Oncology Research
1 week ago
Amgen Inc. South San Francisco, United StatesJOB ID: R LOCATION: US - California - South San Francisco WORK LOCATION TYPE: Flex Commuter / Hybrid DATE POSTED: Mar. 06, 2024 CATEGORY: Research SALARY RANGE: 191,600.00 USD - 236,280.00 USD · HOW MIGHT YOU DEFY IMAGINATION? · If you feel like you're part of something bigger, i ...
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Director, Oncology Research
1 week ago
Amgen South San Francisco, United States**HOW MIGHT YOU DEFY IMAGINATION?** · If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collabor ...
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Associate Director, Oncology
3 weeks ago
Insitro South San Francisco, United StatesThe Opportunity · The heart of insitro's strategy is the combination of advanced machine learning, biology at scale and molecular discovery that address bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team with a passion for ...
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Morgan Lewis San Francisco, United StatesJoin a Legacy of Innovation 110 Years and Counting · Daiichi Sankyo Group is dedicated to the creation and supply of innovative pharmaceutical therapies to improve standards of care and address diversified, unmet medical needs of people globally by leveraging our world-class sci ...
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Regulatory Affairs Director, Oncology
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Oncology Medical Director
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BioSpace, Inc. San Francisco, United StatesCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas ...
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Penfield Search Partners Ltd San Francisco, United StatesOur client is a biotechnology company dedicated to the discovery and development of next-generation cancer treatments. The company has had great success building a clinically differentiated pipeline of small molecules and biotherapeutics, including antibody-drug conjugates, to ta ...
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Director, Oncology Program Management
2 weeks ago
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Director, Oncology Research
1 week ago
Amgen South San Francisco, United States**HOW MIGHT YOU DEFY IMAGINATION?** · If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborator ...
Associate Director, Oncology - San Francisco, United States - Third Rock Ventures
Description
The heart of insitro's strategy is the combination of advanced machine learning, biology at scale and molecular discovery that address bottlenecks in the drug development pipeline.
To accomplish that, we are putting together an incredible team with a passion for target discovery and therapeutics advancement.
Reporting to the Oncology Discovery Therapeutic Area head, you will partner with data science and machine learning (DSML), translational oncology and computational biology colleagues to gain deep insights into the biology and efficacy of antibody drug conjugates (ADCs) with the goal of delivering therapeutics to the right patients.
This will be a hybrid on-site/remote preclinical role, with opportunities to lead projects to drug candidate nomination. You are collaborative, creative, and rigorous and will excel in an exciting environment. This is an excellent opportunity for someone passionate about therapeutic discovery and making an impact on cancer patients
You will join a growing techbio startup that has long-term stability but is very much in formation, providing many opportunities for impact.
You will work with an accomplished versatile team with learning opportunities, and help shape insitro's culture, strategic direction, and outcomes.
Join us, and help make a difference to patientsResponsibilities
Our target starting salary for successful US-based applicants for this role is $175,000 - $195,000.
To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity.
We may also adjust this range in the future based on market data.
This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.
In addition, insitro also provides our employees:
All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
We believe diversity, equity, and inclusion need to be at the foundation of our culture.We strive to bring together diverse teams-grounded in different expertise and life experiences-and ensure those teams succeed in inclusive, growth-oriented environments supported by equitable company and team practices.
You can expect equitable treatment, respect, and fairness throughout the interview process.About insitro
insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines.
At the core of insitro's approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data.
We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease.
These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy.
insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology and metabolism.Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners.
For more information on insitro, please visit
Associate Director, Oncology professionals in San Francisco
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Michelle Sjöberg
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Truc Thien Nguyen-Pham
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