Scientist, Analytical Development, Analytical - Santa Monica, United States - AstraZeneca

AstraZeneca

Verified Company

Santa Monica, United States

2 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

Scientist, Analytical Development, Analytical Sciences

Position Summary

Essential Functions and Responsibilities

Design and develop robust analytical assays for characterizing Tcell therapy drug substance and drug products using flow cytometers and/or other immunoassays.
Author assay development and qualification reports with solid datasets to evaluate assay characteristics.
Perform analytical assays to provide insights for process and product.
Drive assay life cycle, including assay optimization, transfer, and qualification.
Work with Tech Operations crossfunctional teams to draft study protocols, change controls and technical reports.
Support relevant CMC sections for regulatory submissions.
Lead projects and effectively communicate progress or issues in meetings.
Perform routine assays as a QC personnel for drug product release and characterization.

Required Skills/Abilities

PhD in Immunology, Oncology, Cell Biology, or related discipline with 1+ years of relevant academic or industry experience
Indepth knowledge in immunology and cell therapy with handson experience working with T cells is preferred.
Extensive handson experience in executing assays and analyzing data using multicolor flow cytometry (+10 colors).
Firsthand experience in different cellbased assays (e.g., Live imaging, ELISA, or MSD) is preferred.
Prior working experience in a regulated environment (GLP, GMP or QC) is a plus.
Technicaldriven, detailoriented data analysis skills and record keeping abilities.
Excellent verbal, written and presentation skills for scientific studies and projects.
Enjoy a fastpaced, dynamic company environment and able to adjust workload based upon changing priorities.

Physical Requirements

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to:

Sit and talk or hear.
The employee frequently is required to use hands to finger, handle, or feel.
The employee is occasionally required to stand, walk, and reach with hands and arms.
The employee must occasionally lift and/or move up to 10 pounds.
Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.
The noise level in the work environment is usually moderate.
May be required to travel by plane or car 5% of the time.
This position requires working with biological and/or chemical hazards.

Salary Range:
$105,875 - $158,813