- Culture, expand, and bank mammalian cell lines
- Conduct routine transient transfections of HEK and CHO cells at various scales (24-well plates to large shake flasks)
- Develop stable cell pools and clones for both secreted and membrane-bound proteins
- Periodically conduct studies to improve protein expression and yield; evaluate novel expression vectors, host cell lines, and transfection reagents, and present findings at company-wide lab meetings
- Maintain stock of host cell cultures (HEK and CHO), transfection reagents, and culture media
- Contribute to general upkeep of the cell culture lab and cell stocks
- B.S. with 1-3+ years experience
- Proficient in aseptic techniques for culturing mammalian cells in both adherent and suspension formats
- Skilled at expressing proteins in mammalian cell lines, either transiently or stably
- Knowledge of the cell and molecular biology underlying protein expression
- Ability to meticulously document and execute bench work
- Ability to work independently and demonstrates strong problem solving skills
- Curiosity and passion for science demonstrated by reading scientific literature
- Track record of communicating effectively with colleagues and supervisor
- Adaptable and productive in a fast-paced environment
- Available for some weekend work
- Industry experience and proficiency with flow cytometry preferred
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Research Associate - Lebanon, United States - Adimab
Description
Job Description
Job DescriptionTitle: Research Associate - Mammalian Cell Culture
Adimab is the leading technology provider for therapeutic antibody drug discovery, focusing solely on our partnerships without pursuing an internal product pipeline. Since 2009, we have partnered with over 100 pharmaceutical and biotechnology companies, generating more than 450 therapeutic programs, of which more than 60 have entered clinical trials.
Role
We are seeking a Research Associate with experience in mammalian cell culture and protein expression to join our team. This role will support Adimab's novel antibody discovery, maturation, and production platform and closely interface with the Antibody Discovery, Protein Analytics, Molecular Core, and Computational Biology teams.
Responsibilities
Needed upon hire
Come join us
Our integrated antibody discovery and engineering platform provides unprecedented speed from antigen to purified, full-length human IgGs with exquisite specificity and biophysical behavior. We offer fundamental advantages by delivering diverse panels of antibodies that meet the most demanding standards for affinity, epitope specificity, species cross-reactivity, and developability. We enable our partners to rapidly expand their biologics pipelines through a broad spectrum of technology access arrangements.
As a profitable privately-held biotech company, we take a long-term view on value creation and make substantial investments in technology development, research, and our people. We proudly promote meritocracy and reward employees who are productive, use their resources wisely, and make meaningful contributions to the team. We offer individually tailored compensation packages comprised of a competitive salary, meaningful equity, a 2:1 401(k) match, and comprehensive health care benefits.
Located in New Hampshire's beautiful Upper Connecticut River Valley, we are minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and the Dartmouth Hitchcock Medical Center. We are fortunate to be situated in an area that is renowned for its premier skiing, hiking, kayaking, and biking.
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