Research Associate/ Senior Research Associate - Cambridge, United States - GC Therapeutics

GC Therapeutics Cambridge, United States

3 weeks ago

Description

Research Associate/Senior Research Associate, Process Development

Company Overview

GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church's lab, a pioneer insynthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency, and speed. GC Therapeutics is based in Cambridge, MA.For additional information, please visit

Job Purpose

We are seeking a talented and detail-oriented individual to join our growing stem cell research group as a Research Associate. This candidate will be responsible for the maintenance, differentiation, and functional analysis of pluripotent stem cell (PSC) lines and their derivatives to support the development of cell-based therapeutics. The candidate should be familiar with the concept of Design of Experiments (DOE).

Key Responsibilities

General:

Participate in the design, planning and execution of experiments.
Make observations, analyze results, and maintain a detailed laboratory journal.
Summarize results and create presentations for internal group meetings.
Work with other members of the research team and within GCTx to accomplish company goals.
Follow all safe laboratory practices and company policies.

Experimental Techniques:

Execute experiments to support Cell Line Development and Scale up of PSC-derived cells.
Perform experimental endpoint analysis on iPSC and differentiated derivatives including flow cytometry, RT/dd-PCR and microscopy.
Support key lab processes, such as formulating culture media and preparing aliquots.
Collaborate with PD and R&D teams to transfer procedures and protocols between teams.
Assist PD scientists in execution of experiments.
Effectively communicate results, in both written format and oral presentations.
Follow concise protocols for reproducibility of cell culture processes.
Maintain extensive records based on CMC guidelines.
Perform DOE studies, when necessary, to optimize parameters affecting engineered cell line differentiation and stability.

Qualifications

Essential Qualifications:

BSc with 3+ years or MSc with 1+ years of relevant industry experience in molecular and cellular biology, bioengineering, biochemistry, or related discipline.
Experience with PSC cell culture, expansion, banking, and differentiation is a must.
Hands-on experience in molecular biology laboratory techniques.
Hands-on experience in analytical techniques relevant to the characterization of PSCs.
Strong project management and organizational skills, with ability to prioritize and multitask.
Effective communicator with excellent interpersonal skills.
Ability to work in a laboratory environment approximately 75% of the time including weekend hours.

Additional Qualifications:

Hands-on experience with multi-tray flasks is desirable.
Experience with Single-Use technologies is desirable.
Experience in gene expression analysis and next generation sequencing is desirable.
Familiarity with techniques used to measure genome integrity and off target characterization is desirable.
Familiarity with automation and cell cloning.
Ability to conduct high quality presentations at internal meetings.
Familiarity with working in cleanrooms under cGMP guidelines is desirable.
Basic knowledge of cell culture manufacturing principles, risk assessments (FMEA), Chemistry, Manufacturing, and Controls (CMC) principles, and tech transfer.

Equal Opportunity Workplace: GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics' equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.

Research Associate

3 days ago

Apex Systems Cambridge, United States Contract

Job#: · Job Description: · Seeking a Research Associate, Molecular Biology to join a Biotech company in the Cambridge, MA area. · Position summary: · We are looking for a meticulous Research Associate with a growth mindset and a passion for biology research. The successful can ...
Research Associate

3 weeks ago

Charles River Cambridge, United States

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
Research Associate

3 weeks ago

Charles River Laboratories, Inc. Cambridge, United States

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
Research Associate/Research Scientist

2 weeks ago

Harvard University Cambridge, United States

Department/Area · Center for Biostatistics in AIDS Research Position Description The Department of Biostatistics at the Harvard T.H. Chan School of Public Health has an immediate opening in the Center for Biostatistics in AIDS Research for a PhD-level Research Associate or Resea ...
Research Associate

21 hours ago

Nikon Boston, United States

Research Associate - Code: 2351 · Overall responsibilities: · Nikon Instruments Inc, a globally recognized leader in microscopy and bio-imaging solutions, has established the Nikon BioImaging Lab (NBIL) in the Greater Boston Area to provide contract imaging and assay developmen ...
Scientific assistant/research associate

2 weeks ago

FusionWorks Cambridge, United States

Waterways are complex water systems. The Federal Institute of Hydrology (BfG), located within the Federal Ministry of Digital and Transport (BMDV), works to make them sustainable and efficient. As the federal scientific institute for research, evaluation, and consultation in the ...
Research Associate

3 weeks ago

Harvard University Cambridge, United States

Basic Qualifications · Bachelor's degree required, along with research experience gained through work experience, internships, or academic work. · Additional Information · This position is a fully benefits-eligible term appointment ending one year from date of hire, with possibil ...
Research Associate

3 weeks ago

Inari Cambridge, United States

About Inari... · Inari is the SEEDesign company. We embrace the diversity and complexity of nature in every aspect of our business to drive innovation - to push the boundaries of what is possible. Through our unrivaled technology platform, Inari uses predictive design and advance ...
Research Associate

3 weeks ago

Forrester Research, Inc. Cambridge, United States

At Forrester, we're trusted to work on trailblazing, mission critical problems that business and technology leaders face today. That's why we're always looking to empower talented individuals to perform at their best every single day. We're proud of our community of smart people ...
Research Associate

3 weeks ago

Integrated Resources, Inc Cambridge, United States

Job Description · Job DescriptionJob Title: Research Associate · Job Location: Cambridge, MA · Job Duration: 06+ Months · Shift: Mon- Fri · How will your role help us transform hope into reality?This position offers the opportunity to impact a growing portfolio of targeted therap ...
Research Associate

3 weeks ago

Charles River Laboratories Cambridge, United States

Research Associate , Imaging · Req ID #: 222988 · Location: · Cambridge, MA, US, 02139 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a signif ...
Research Associate

1 day ago

Forrester Cambridge, United States

At Forrester, we're trusted to work on trailblazing, mission critical problems that business and technology leaders face today. That's why we're always looking to empower talented individuals to perform at their best every single day. We're proud of our community of smart people ...
Associate/ Research Associate

3 weeks ago

Synapse Energy Economics Cambridge, United States

Synapse Energy Economics is a research and consulting firm specializing in energy, economic, and environmental topics with a focus on resource and policy issues in the electric industry. Our work supports a broad range of public-interest clients, including consumer advocates, env ...
Research Associate

3 weeks ago

Charles River Laboratories Cambridge, United States

Research Associate , Imaging · Req ID #: 222988 · Location: · Cambridge, MA, US, 02139 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a signif ...
Research Associate

3 weeks ago

The Fountain Group Cambridge, United States

The Fountain Group. We are a national staffing firm and are currently seeking a Research Assocaite for a prominent client of ours. This position is located in Cambridge, MA. Details for the position are as follows: · Job Description: This position offers the opportunity to impac ...
Research Associate

2 weeks ago

Integrated Resources Cambridge, United States

Job Title: Research Associate · Job Location: Cambridge, MA · Job Duration: 06+ Months · Shift: Mon- Fri · How will your role help us transform hope into reality? · This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innova ...
Research Associate

1 week ago

Bristol-Myers Squibb Cambridge, United States

**Working with Us** · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a productio ...
Research Associate

3 weeks ago

LifeCanvas Technologies Cambridge, United States

LifeCanvas Technologies is an MIT spinoff venture aiming to revolutionize the way we see and study biological systems to elevate human health. LifeCanvas offers cutting-edge technologies and end-to-end solutions that enable holistic molecular imaging of biological systems to acce ...
Research Associate

1 week ago

Bristol-Myers Squibb Cambridge, United States

Working with Us · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production li ...
Research Associate

5 days ago

Forrester Cambridge, United States

At Forrester, we're trusted to work on trailblazing, mission critical problems that business and technology leaders face today. That's why we're always looking to empower talented individuals to perform at their best every single day. We're proud of our community of smart people ...