-
Principal Scientist
2 weeks ago
Novartis Cambridge, United States**Summary**: · **About the Role**: · **Major accountabilities**: · **Onsite Role LI:#Onsite** · Your responsibilities will include, but not limited to: · - Develop and validate targeted protein/peptide singleplex/multiplex biomarker assays by working in internal labs as well as g ...
-
Principal Scientist, Immunopeptidomics
1 week ago
Johnson & Johnson Cambridge, United StatesJohnson and Johnson is recruiting for a **Principal Scientist, Immunopeptidomics & Proteomics **for our site located in Cambridge, MA. · **Primary responsibilities**: · - Manage a team of wet lab scientists enabling proteomic insights across a wide variety of programs and therape ...
-
Clinical Scientist Principal
3 weeks ago
Vertex Pharmaceuticals Boston, United StatesJob Description · General Summary: · The Clinical Scientist Principal will provide scientific, clinical, and operational input to early and late stage clinical development programs with an emphasis on protocol-specific, in-life clinical data monitoring activities. This role will ...
-
Principal Scientist
3 days ago
Nuvalent, Inc. Cambridge, United StatesThe Company:With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a ...
-
Principal Data Scientist
1 week ago
Citizens Boston, United States**Description** · As a part the Central Model Development team, you're made ready for a fulfilling career with exciting new challenges and opportunities to stretch yourself. The ALM Data Scientist will design and build securities, loan and deposit exposure and pricing models used ...
-
Principal Scientist, Translational Modeling
2 weeks ago
Novartis Cambridge, United States**About the Role**: · The position is located in Cambridge, MA and will not have the ability to be located remotely. · LI-Hybrid · About the role: · We are seeking an experienced translational modeler eager to accelerate drug discovery & development by facilitating rigorous decis ...
-
Gcp Bioanalysis Principal Scientist
2 weeks ago
Novartis Cambridge, United States**About the Role**: · Onsite · About the role: · Your Key Responsibilities: · - Designing, developing, validating assays and performing clinical sample analysis using biological techniques for PK, PD and immunogenicity following SOPs and guidelines in a supervisory role · - Parti ...
-
Principal Scientist, Discovery and Translational
2 weeks ago
Novartis Cambridge, United States**Summary**: · **About the Role**: · About the Role: · - Essential Requirements: · - Ph.D or MD/Ph.D or equivalent training. · - At least 3 years of postdoctoral experience in industry or equivalent. · - Pharmacology expertise in renal biology (preferred) and/or general drug disc ...
-
Principal Scientist
3 days ago
Eurofins USA PSS Insourcing Solutions Cambridge, United StatesJob Description · Job DescriptionCompany Description · Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustaina ...
-
Principal Scientist Ii, Drug Discovery
2 weeks ago
Novartis Cambridge, United States**Summary**: · Internal Job Title: Principal Scientist II Job Location: Cambridge, MA onsite About the role: We are seeking an innovative and dynamic scientist with broad expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for p ...
-
Principal Scientist
4 weeks ago
GALY Boston, MA, United StatesWe are seeking a Principal or Distinguished Scientist specializing in cotton fiber development to guide our efforts in isolating, cultivating, and optimizing stable plant stem cell lines for fiber production. The ideal candidate will have deep knowledge and experience in cotton c ...
-
Principal Scientist I, Drug Discovery
2 weeks ago
Novartis Cambridge, United States**Summary**: · Internal Job Title: Principal Scientist I Role Location: Cambridge, MA, onsite About the role: We are seeking a motivated scientist with expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with r ...
-
Principal Scientist, Translational Medicine
2 days ago
Bristol-Myers Squibb Cambridge, United States**Working with Us** · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production ...
-
Principal Scientist, Translational Discovery
2 days ago
Bristol-Myers Squibb Cambridge, United States**Working with Us** · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production ...
-
Principal Scientist
2 weeks ago
Nestlé Health Science Holbrook, United StatesPrincipal Scientist · - Nestlé Nutrition R&D Centers, Inc. seeks a Principal Scientist in Holbrook NY- Duties: Proactively identify consumer centric packaging technologies and strategies to solve or enable knowledge discovery involving sustainability, recycling, product, or other ...
-
Principal Scientist, Oncology Research
1 week ago
Aktis Oncology Inc Boston, United States**Description**: · **Background/Training**: · - Ph.D. in biological sciences or related field, preferably related to oncology or cancer biology · - 2-8 years of biopharmaceutical research experience in drug discovery and/or translational research · **Experience/Accomplishments** ...
-
Bristol-Myers Squibb Cambridge, United States**Working with Us** · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production ...
-
Amgen Cambridge, United States**HOW MIGHT YOU DEFY IMAGINATION?** · You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission—to serve patient ...
-
Principal Scientist
2 weeks ago
Nuvalent Inc. Cambridge, United StatesThe Company: · With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with ...
-
Principal Scientist
3 days ago
Newton Colmore Consulting Cambridge, United StatesPrincipal Scientist - Protein Engineering - Cambridge, MA · Newton Colmore is partnered with a biotech company in Cambridge MA, and we are searching for a principal-level scientist with expertise in protein engineering. · As a Principal Scientist within this organisation, you w ...
Process Development Senior Principal Scientist - Cambridge, MA, United States - Amgen
Description
Career CategoryProcess DevelopmentJob DescriptionHOW MIGHT YOU DEFY IMAGINATION?If you feel like you're part of something bigger, it's because you are.
Process Development Senior Principal Scientist - CMC Team LeadLiveWhat you will doLet's do this. Let's change the world.
In this vital role you will lead a team of scientists focused on the development and qualification of analytical methods, the characterization of protein-based biologic therapies, and supporting process development activities.
At Amgen, our mission to serve patients drive all that we do. Come join us to work alongside talented scientific colleagues to advance Amgen's innovative pipeline of therapies.Lead a team of scientists focused on method development and molecule characterization for biologics in late-stage development serving as a mentor, sponsor, and coach with emphasis on people-centered leadership.
Serve as the Attribute Sciences team lead on a cross-functional product development team for a biologic in late-stage development with accountability of key decisions, strategies, and deliverables within the analytical sciences space.
Author chemistry, manufacturing and controls (CMC) sections in regulatory files, lead the preparation of responses to analytical related questions from health authorities, and support pre-approval inspections.
Establish strong partnerships with leaders from multiple functions across Amgen to achieve program deliverables.Expert knowledge in the analysis of protein-based therapies with advanced techniques such as capillary electrophoresis, liquid chromatography, and mass spectrometry.
Solid understanding of cGMP / ICH regulations and compendial guidelines with the ability to apply them to analytical development.Ability to develop and implement integrated control strategies for critical quality attributes of biologic therapeutics.
Develop and document standard operating procedures, protocols and reports.
Develop novel process or approaches to tackle complex problems.
WinWhat we expect of youWe are all different, yet we all use our unique contributions to serve patients. The Senior Principal Scientist professional we seek is a leader with these qualifications.
Basic Qualifications:
Bachelor's degree and 7 years of scientific / pharmaceutical experience ORMaster's degree and 5 years of scientific / pharmaceutical experience ORDoctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of scientific / pharmaceutical experience
Preferred Qualifications:
Degree in analytical chemistry, physical chemistry, biochemistry, pharmaceutical sciences, or related discipline.
Strong people-leadership skills and experience with leading a team of direct reports.
Excellent laboratory skills with 7+ years of laboratory research or experience in industry. laboratories supporting analysis and characterization of protein therapies.
Advanced technical expertise in analytical methodologies used to characterize protein therapeutics including CE-SDS, cIEF / icIEF, HIC, SEC, IEX, RP, HILIC, MS, etc.
Expertise with handling, troubleshooting, and maintaining CE and LC instruments.Expertise using CE and LC operation and data analysis software.
Experience with data processing and statistical analysis software tools.
Ability to independently prioritize, schedule, and lead multiple tasks to meet results.
Proven ability to lead complex projects or work packages.
Ability to work in a matrix team environment and collaborate effectively.
Excellent written and oral communication skills.
Experience with use of electronic notebooks.
Firsthand experience with method qualifications and transfers.
Skilled in phase appropriate GMP compliance and documentation.
ThriveWhat you can expect of usAs we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.
In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.
Apply nowfor a career that defies imaginationIn our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt.
Join is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
Please contact us to request accommodation.#obesity.Salary Range157,242.00 USD - 182,988.
00 USDSummaryLocation:
US - Massachusetts - CambridgeType: Full time
