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    Clinical Research Scientist - South San Francisco, CA, United States - Abbvie

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    Full time
    Description

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.

    We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.

    For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

    The Biologics CMC Development team at AbbVie in the Bay Area has a long and rich history of biologics development.

    Now located in a new state of the art facility in South San Francisco, the team leverages its comprehensive end-to-end CMC capabilities to work collaboratively through all phases of CMC development with a primary focus on advancing complex biologic therapies, such as bi-specifics and novel modalities, to human clinical studies and eventual licensure.

    This Scientist I role is within a team of highly experienced scientists and managers who have directly enabled the development/IND submissions of 20+ novel oncology drugs and successfully filed two BLAs.

    This position is an onsite role in a lab-based function.

    To be successful candidates must enjoy and thrive in an onsite, highly collaborative lab environment with daily face-to-face cross-functional interactions between scientists.

    Support transfer processes to GMP manufacturing site for clinical material production
    Work efficiently, collaboratively, and cross-functionally toward project timelines and goals
    Work with contract labs and carry out viral clearance studies
    Bachelor's Degree or equivalent education and typically 5 years of experience and MS or equivalent education and typically 2 years of experience
    Must have protein purification experience including chromatography separations and filtration operations
    Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions
    Has understanding of biochemistry and bioprocess engineering concepts
    Has strong planning and analytical skills
    Demonstrated scientific writing skills and strong verbal communication skills including scientific data presentations
    Has proficiency with Microsoft Office software, ability to learn new software applications

    Has hands on experience with executing antibody or antibody-like molecule purification techniques including resin chromatography (affinity, CEX, AEX, MMC), depth filtration, virus filtration, membrane chromatography, and TFF operations.

    Has hands on experience with monoclonal antibody or antibody-like molecule purification at GMP, pilot and/or laboratory scale
    Understanding of analytical techniques, such as HPLC, LAL, and ELISA
    Has hands on experience with high-throughput technologies and automation
    Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

    We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

    This job is eligible to participate in our short-term incentive programs. ​

    AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.

    It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.


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