Scientist I/ii - Cambridge, United States - Nvelop Therapeutics

Description

Position Overview

Responsibilities:

• Significantly contribute to in vivo study methodologies including dose preparation of test articles, IV/RO injections, retroorbital blood sampling, necropsy at EOS.
• Work closely with the _in vivo_ pharmacologist aspects of multiple projects within discovery and development.
• Propose, plan, coordinate, and supervise study execution at external Contract Research Organizations (CROs).
• Develop and implement new animal models to improve _in vivo_ pharmacology studies.
• Write Institutional Animal Care and Use Committee (IACUC) protocols and ensure compliance.
• Analyze data from _in vivo_ pharmacology and efficacy studies.
• Contribute to study reports, potential regulatory filings, and project presentations.
• Maintain excellent written documentation of completed experiments.

Who you are:

• Ph.

D. in Biology, Immunology, Pharmacology, or related fields with 0 - 5 years post graduate experience, or BSc with 5 plus year experience in industry

• Extensive handson experience and familiarity with _in vivo_ animal models, including manipulation, dosing, necropsy, and tissue dissociation.
• Have experience working with tissue dissociation and _ex vivo_ samples.
• Have experience with multicolor flow cytometry.

- mammalian cell culture, in vitro assay designs, and related cell/molecular biology methods is a plus.

• Experience with multicolor and high dimensional flow cytometry is a plus.
• Strong problemsolving, organization, and communication skills
• Ability to work independently as well as part of a team.
• Ability to adapt to a fastpaced environment and pivot to support ongoing needs.