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Research Scientist - Washington, United States - George Washington University
Description
I. DEPARTMENT INFORMATION
Job Description Summary:
The Watkins' lab at George Washington University is seeking an energetic, motivated individual to join our team and lead our Protein Biochemistry and Biophysics work. The Research Scientist will be expected to design/engineer proteins and carry out purification and biophysical/functional characterization of tagged and untagged proteins. These engineered antigens and antibodies will need to be expressed in either mammalian or bacterial systems. This position is responsible for planning, conducting and supervising research at a high level, by designing and conducting experiments in a controlled laboratory setting. Using extensive experience and judgment, this role will plan independent research, analyze and interpret data, publish results, represent the university at conferences and meetings, develop new theories and methodologies, and will lead and direct the work of lower level research staff, while transferring technical expertise. Responsibilities include:
• Performs high-through put screens for protein function, interaction, and expression.
• Engineers proteins via directed evolution for a next generation protein sequencing platform and develops novel biochemical and molecular assays.
• Conducts protein-ligand mechanistic studies and characterization is desired (e.g. ELISA, SPR, Octet, SEC-MALS, MST, NanoDSF).
• Performs protein engineering, production, and purification from E. coli, insect cell, and mammalian expression systems.
Performs other related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.
Minimum Qualifications:
Qualified candidates will hold a Master's degree plus 5 years of experience or a PhD plus 2 years of experience in a related discipline to include at least 2 years of research and/or college level teaching in a field basic to the work to be performed. Degree must be conferred by the start date of the position.
Additional Required Licenses/Certifications/Posting Specific Minimum Qualifications:
Preferred Qualifications:
• Proficiency in a structural imaging program (eg. PyMOL).
• Experience in microbiology, biochemistry or biophysics.
• Proficiency in a structural imaging program (eg. PyMOL).
• Clarity in communication as well as flexibility to adjust to a dynamic, high-paced research environment with shifting priories and deadlines. .
• Familiarity with a variety of expression systems, protein structures and common characteristics. Knowledge of AKTA instrumentation and a broad range of purification techniques (affinity chromatography, ion exchange, size exclusion, mixed mode)
- Experience with different protein purification approaches such as affinity (His-tag, Fc-fusion), cation- and anion-exchange, size-exclusion chromatography (SEC).
• Experience with protein characterization techniques, such as SDS-PAGE and Western Blot.
Typical Hiring Range
Commensurate with experience. II. POSITION INFORMATION
Campus Location:
Foggy Bottom, Washington, D.C.College/School/Department:
School of Medicine and Health Sciences (SMHS)Family
Research and LabsSub-Family
Field ResearchStream
Individual ContributorLevel
Level 4Full-Time/Part-Time:
Full time -> FTE 1.00Hours Per Week:
40Work Schedule:
Monday through Friday, 8:30am - 5:00pmWill this job require the employee to work on site?
YesEmployee Onsite Status
On-campus (in person)Telework:
NoRequired Background Check
Criminal History Screening, Education/Degree/Certifications Verification, Social Security Number Trace, and Sex Offender Registry SearchSpecial Instructions to Applicants:
Employer will not sponsor for employment Visa status
Internal Applicants Only?
NoPosting Number:
R001698Job Open Date:
10/19/2023Job Close Date:
If temporary, grant funded or limited term appointment, position funded until:
Background Screening
Successful Completion of a Background Screening will be required as a condition of hire.EEO Statement:
The university is an Equal Employment Opportunity/Affirmative Action employer that does not unlawfully discriminate in any of its programs or activities on the basis of race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity or expression, or on any other basis prohibited by applicable law.
