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AstraZeneca PLC Waltham, United StatesJob Title: Senior Director, Early Oncology Precision Medicine · Cambridge (UK) or Waltham; MA (US) · Join our Oncology R&D team as a Senior Director, Precision Medicine, Antibody Drug Conjugates & Computational Pathology. You will be accountable for ensuring that diagnostic tests ...
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AstraZeneca Waltham, MA, United StatesJob Title: Senior Director, Early Oncology Precision MedicineCambridge (UK) or Waltham; MA (US)Join our Oncology R&D team as a Senior Director, Precision Medicine Lead, Early Oncology (Antibody Drug Conjugates).You will be accountable for ensuring that diagnostic tests or equival ...
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AstraZeneca Waltham, United StatesJob Description · Are you passionate about the role Data Science can make in innovating clinical trials for emerging products? · AstraZeneca is a company that follows the science and turns ideas into life changing medicines. Innovative technologies are allowing us to better captu ...
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AstraZeneca PLC Waltham, United StatesSenior Scientist, Mass Spectrometry, Early Oncology · Join our Boston R&D chemistry team as a Senior Scientist, where you'll use your expertise in small-molecule mass spectrometry to analyze a wide range of drug-like small molecules, linkers, payloads, and new modalities using UH ...
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AstraZeneca Waltham, United StatesJob Description · Senior Scientist, Mass Spectrometry, Early Oncology · Join our Boston R&D chemistry team as a Senior Scientist, where you'll use your expertise in small-molecule mass spectrometry to analyze a wide range of drug-like small molecules, linkers, payloads, and new ...
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AstraZeneca Waltham, United States Full timeStatistical Science Associate Director, Early Oncology · Wilmington, Waltham or Gaithersburg · Play a meaningful role in making our pipeline accessible to patients. · Do you have expertise in, and passion for, Biostats? Would you like to apply your skills to impact all phases ...
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AstraZeneca PLC Waltham, MA, United StatesSr. Scientist, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Our pioneering oncology p ...
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AstraZeneca PLC Waltham, United StatesAssociate Director, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Our pioneering oncol ...
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AstraZeneca PLC Waltham, United StatesIntroduction to role: · Join us at AstraZeneca as a Senior Director Clinical Program (SDCP) in our Oncology R&D department This role offers a significant scope, including accountability for the clinical program strategy and operational design inputs to deliver assigned programs. ...
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AstraZeneca Waltham, United StatesAbout AstraZeneca At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collabor ...
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AstraZeneca Waltham, United StatesAbout AstraZeneca At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collabor ...
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AstraZeneca Waltham, United StatesJob Description · Associate Director, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Ou ...
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AstraZeneca Waltham, United StatesAssociate Director, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Our pioneering onco ...
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AstraZeneca Waltham, United StatesJob Description · Are you a seasoned Early Clinical Scientist with experience in supporting Phase 1-2 studies? Do you have a keen interest in working across a variety of platforms such as IO, Antibody Drug Conjugates, Cell Therapy, Tumor Drivers and Resistance, Epigenetics and DN ...
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AstraZeneca Waltham, MA, United StatesAbout AstraZeneca At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collabor ...
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AstraZeneca PLC Waltham, United StatesIntroduction to role: · Join us in our mission to eliminate cancer as a cause of death. As the Director Study Leader Human Biological Sample (HBS) Specialist in Early Oncology Clinical (EOC), you will be responsible for delivering complex studies and managing best practices acros ...
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AstraZeneca PLC Waltham, MA, United StatesAssociate Principal Scientist, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Our pione ...
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AstraZeneca Waltham, MA, United StatesAssociate Principal Scientist, Medicinal Chemistry, TTD, Early Oncology · Location: Waltham, MA, US · Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines. Our pi ...
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AstraZeneca PLC Waltham, United StatesAstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical ...
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AstraZeneca PLC Waltham, United StatesThe Director - Cell Therapy Operations has a sizeable scope, including accountability for the operational design inputs to deliver the assigned program(s) as part of the product development team. Within a program, they maintain accountability for the delivery and reporting of cli ...
Associate Director, Medicinal Chemistry, TTD, Early Oncology - Waltham, United States - AstraZeneca
Description
Associate Director, Medicinal Chemistry, TTD, Early OncologyLocation: Waltham, MA, USDo you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life changing medicines.
Our mission is to make a meaningful difference to patient health through great medicines that bring benefit for patients and add new value for society.
We discover, develop, manufacture and market prescription medicines for important areas of healthcare, which include some of the worlds most serious illnesses:cancer, cardiovascular disease, respiratory, inflammation, and autoimmune diseases.
We are driven by a shared goal to make a positive impact on the lives of patients with these serious diseases.
Oncology is a core therapy area and growth platform at AstraZeneca and our vision is to deliver life-changing medicines that improve outcomes for patients most in need.
This OpportunityThe Associate Director will actively lead programs involving small molecule drug design in tumor targeted delivery (TTD) chemistry group.
This role is part of our strategy to deliver next generation of therapeutics including, but not limited to, small molecule, peptide and antibody drug conjugates to treat cancer.
For this purpose, small molecule discovery strategies will be deployed (i.e., hit-ID, SBDD/LBDD/LipE/FQ-directed hit-to-lead and lead optimization). Close collaboration with computational chemistry, in vivo pharmacology, structure biology, and related functions will be required. The role will also include line-management and lab operations responsibilities. This job posting is for our group Greater Boston/Waltham location.Core Accountabilities:
Design and develop modular strategies compatible for rapid access to small molecule targets (strong organic synthesis and medicinal chemistry background is required)
Guide discovery of novel/differentiated small molecule candidates with optimal structural, pharmacological, physicochemical, metabolic, and safety considerationsDemonstrate strategic thinking in program activities and people management, actively organize team meetings, and present regular scientific/management updates to leadershipPrioritize deliverables and projects in fast pace environmentDemonstrate creativity, problem-solving and critical thinking skills to overcome challenges all while building/strengthening IP Closely collaborate with cross-functional leads and leverage CRO resources to meet timelines Exhibit leadership and team-player qualities and demonstrate willingness to develop younger colleagues and foster mentorship Ensure that appropriate safety, health & environment (SHE) practices are followed in the labBasic Qualifications:
Doctoral degree (Ph.
D.) focused on synthetic organic chemistry or medicinal chemistry with 5+ years of experience in biotech and/or pharmaceutical industry setting.
A strong track record of scientific innovation as medicinal chemistry project lead and portfolio milestone success Excellent communication skills, team building experience in professional setting with 2+ years of line-management experienceDeep knowledge of ADME, physicochemical, biochemical, and pharmacological principles as applied to small molecules Past record of success in creativity and problem-solving (e.g., peer-reviewed publications and patents)Subject matter expert in organic synthesis and methodology, with general knowledge of the mechanisms of chemical reactivity and awareness of latest scientific literature to guide the chemistry teamStrong work ethic with desire to mentor and develop directly/indirectly reporting colleagues Site LocationThe Waltham R&D site is home to our small-molecule oncology research in North America.
It is situated within a biopharma cluster of academic research institutions, medical centers, pharmaceutical companies and biotech start-ups. The Boston region is consistently ranked #1 globally for biotech research, investment, talent recruitment and lab space.The campus, also known as the Boston BioHub, is one of the largest and most dynamic life-science research hubs in the region.
It is home to more than 800 scientists and experts working in nine different pharmaceutical and biotech companies.The site is also home to the AstraZeneca Incubator, a program that helps emerging companies advance novel and innovative healthcare solutions to meet the needs of patients.
Plenty of free covered/uncovered parking is available along with charging stations for electric vehicles. Additionally, shuttle service to local transportation hubs is also available.Why AstraZeneca?At AstraZeneca, we are dedicated to being a Great Place to Work. A place where employees are empowered to push the boundaries of science and unleash their entrepreneurial spirit. There is no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.
So, what is next?A place built on courage, curiosity, and collaboration we make bold decisions driven by patient outcomes.
Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline.
If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we want to hear from youDate Posted05-Feb-2024Closing DateOur mission is to build an inclusive and equitable environment.
We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
SummaryLocation:
US - Waltham - MAType: Full time
