Senior Scientist LCMS - Malvern - Resolian

    Resolian
    Resolian Malvern

    1 day ago

    Description

    Responsibilities

    · Prepare reagents, standards, and control samples

    · Analyze samples using various techniques specific to department

    · Independently design and develop methods

    · Perform method validation or qualification

    · Operate analytical equipment

    · Technical resource for troubleshooting activities; assays and equipment

    · Maintain analytical equipment

    · Review, evaluate, and interpret data results

    · Draft and present posters/presentations

    · Train and mentor lower level Scientists

    · Collaborate with clients and vendors

    · Ensure lab area is clean and inspection ready at all times

    · Remove lab waste

    · Collaborate across teams, departments, and sites

    · Evaluate and establish processes to improve quality and efficiency

    · Record tasks in accordance with Good Documentation Practices (GDP)

    · Knowledge of regulatory requirements; GLP, GCP, 21CFR Part 11

    · Follow applicable SOPs and procedural documents

    · Other tasks as assigned

    Skills, Education & Qualifications

    • BA degree with at least 5 years of experience; MS degree with at least 3 years of experience; Ph.D. degree with at least 2 years of experience. Experience must be in LC-MS bioanalysis.
    • Knowledge and understanding of regulatory requirements; GLP, GCP, 21CFR Part 11, GDP.
    • Knowledge and understanding of LC-MS instrumentation, along with hands-on experience.
    • Proficient and professional communication skills, both verbal and written.
    • Ability to resolve challenges independently and to coach junior team members.
    • Ability to use computer systems, Microsoft Office software, LIMS, and instrument software.

    Preferred

    • Advanced degree with over 5 years of experience in regulated LC-MS bioanalysis. Experience with CRO is a plus.
    • Experience in leading regulated bioanalytical projects using LC-MS.
    • Knowledge of chromatographic chemistry and the ability to independently develop LC-MS bioanalytical methods.
    • Experience in daily maintenance and troubleshooting of LC-MS instruments, especially Sciex Triple Quad and Thermo Orbitrap systems.
    • Knowledge of LC-MS bioanalysis for various modalities, including small molecules, oligonucleotides, PMOs, peptides, proteins, ADCs, and lipids is a plus.
    • Experience in leading and managing a small scientific group.
    • Hands-on experience with Watson LIMS. Experience with Sciex Analyst, Shimazu LabSolutions, and Thermo Chromeleon is a plus.

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