- Contribute to and lead initiatives to design and analyze engineered mammalian cell lines by developing robust and innovative computational approaches that utilize mechanistic models, multiomics, machine learning, deep learning, and AI.
- Work closely with bench scientists to develop experimental plans and analyze quantitative measurements with statistical rigor to gain biological insights and to train and validate models.
- Regularly dive deep into the multiomics stack to innovate on analysis techniques, algorithms, models.
- Present findings to our team, leadership, and partners.
- Pair with our software engineers to transition impactful computational approaches into our commercial software offerings.
- Contribute to Asimov's long-term computational biology strategy.
- You are a highly skilled researcher and innovator with at least 5 years of experience in industry or academic research and with a published track record of developing new, impactful approaches to computational biology. A strong foundation in statistics and experimental design is a plus.
- You are passionate about joining a startup where teamwork, passion to learn, and excitement to engineer biology take precedence over process and ego.
- You have broad, proven expertise in solving difficult biology problems utilizing both classical and new computational biology approaches, including working with large multiomics datasets, machine learning techniques, deep learning methods, and AI/LLM-based approaches. Demonstrated interest in engineering biology is a plus.
- You have extensive knowledge of molecular biology and cellular biology, particularly in mammalian systems and/or cellular production systems.
- You have deep knowledge of public biological databases and their application for mammalian cell biology.
- You are expert in Python, R, and common bioinformatic toolkits, as well as with computational notebooks (Jupyter), version control (Git), and coding best-practices. You also have experience with cloud computing environments (GCP) and databases (SQL).
- You have a record of working closely with wet lab scientists to design experiments and interpret data to most effectively extract statistically and biologically meaningful insights.
- Experience with developing data applications (Streamlit, PyWebIO, Flask, Dash) is a plus.
-
Computational Biologist
2 days ago
GALY Boston, United StatesWe are out of time. Change must be immediate. We have to help the world find alternative ways to produce all the same things we love. But better. Using less land, less water, less energy, and making less waste. If you think that sounds like a mission, well, you are right. We are ...
-
Senior Computational Biologist
2 weeks ago
Pfizer Cambridge, United States Full timeWHY PATIENTS NEED YOU · Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Wh ...
-
Senior Scientist, Computational Biologist
2 weeks ago
Harbinger Health Cambridge, United StatesHarbinger Health is pioneering the detection of early cancer and enabling foundationally new approaches to cancer screening, diagnosis, and management. Incubated within Flagship Pioneering for three years before launching in 2021, Harbinger combines advances in artificial intelli ...
-
Associate Computational Biologist, R&D
4 weeks ago
CATALOG Charlestown, United StatesJob Description · Job DescriptionCATALOG, a Boston-based pioneering startup, is making significant strides in the field of data storage and computation by harnessing the power of DNA. DNA, known for its millennia-long stability, unrivaled information density, and cost-effective r ...
-
Applied Computational Biologist, Renal I
2 weeks ago
Novartis Cambridge, United States**About the Role**: · Internal Job Title: Senior Expert I, Data Science · Role Location: Cambridge, MA, onsite · About this role: · Key Responsibilities: · - Working closely with a core team of Translational Research & Data Science scientists fluent in wet and dry lab practices · ...
-
Bioinformaticist (Wiggs, Segre)
2 weeks ago
Massachusetts Eye and Ear Boston, United States Full timeWe are seeking a highly qualified and motivated Bioinformaticist or Computational Biologist to join our collaborative team in the Ocular Genomics Institute and the Department of Ophthalmology at Massachusetts Eye and Ear (MEE), Harvard Medical School, to work on innovative projec ...
-
Scientist II, Computational Biology
2 weeks ago
Foundation Medicine Boston, United States Full timeAbout the Job · The Scientist II, Computational Biology on the Computational Biology Team provides computational, bioinformatic and statistical activities to enrich the analytical capabilities of existing products as medical knowledge advances, as well as to design and build lab ...
-
Machine Learning Engineer
1 week ago
Harvard University Boston, United States Full timeAbout the Position: · The Center for Computational Biomedicine (CCB) at Harvard Medical School (HMS) is looking for a Machine Learning Engineer with expertise in developing large language models (LLMs) to advance CCB's mission to leverage data and computation to transform researc ...
-
Molecular Pharmacologist
4 weeks ago
Kojin Therapeutics Boston, United StatesWe are seeking an initiative-taking, creative, and curious scientist to join our growing preclinical pharmacology team. The ideal candidate will have solid molecular pharmacology background related to cancer or other diseases, demonstrated experience in studying mechanisms involv ...
-
Preclinical/Translational Pharmacologist
4 weeks ago
Kojin Therapeutics Boston, United StatesWe are seeking a preclinical/translational pharmacologist with experience in developing oncology small-molecule therapeutics. The ideal candidate would have solid experience in designing and conducting preclinical/translational pharmacology studies and be knowledgeable in molecul ...
-
Vesalius : Statistical Geneticist
1 week ago
Flagship Pioneering Cambridge, United StatesStatistical Geneticist · Vesalius Therapeutics is seeking a highly motivated and collaborative Statistical Geneticist to leverage human genetic and genomic data to reveal biological mechanisms of health and disease. You will report to the VP, Informatics & Data Science and coll ...
-
Group Leader, Computational Biology, Xavier Lab
4 weeks ago
Broad Institute Cambridge, United StatesDescription & Requirements · The Infectious Disease and Microbiome Program (IDMP) is looking for a Group Leader in Computational Biology to lead and direct investigations into the mechanisms of host microbiome interactions in health and disease. We are an interdisciplinary grou ...
-
Temp Conservation Biologist I
1 day ago
State of Nebraska Cambridge, United StatesThe work we do matters · Hiring Agency: · Game & Parks Commission - Agency 33 · Location: · Cambridge Job Posting · Hiring Rate: · $14.845 · Classification Salary Range: · $ $21.88 · Job Posting: · JR Temp Conservation Biologist I (Open) · Applications No Longer Accepted On (If ...
-
Software Engineer II
1 week ago
Editas Medicine Cambridge, United States Full timeAt Editas, we're driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRI ...
-
Senior Research Associate
4 weeks ago
Broad Institute Cambridge, United StatesDescription & Requirements · Detailed studies of cellular signaling networks related to protein phosphorylation, ubiquitylation or acetylation · Unveiling the targets of drugs or identifying protein interactors through chemical proteomics technologies and affinity purification ...
-
Lab Technician, PRISM
2 weeks ago
Skills Alliance Cambridge, United StatesJOB TITLE · Lab Technician, PRISM · JOB DESCRIPTION · Our client's PRISM team, a core group of the Cancer Program, is seeking an exceptional candidate to join our dynamic and growing research team. This position affords the exciting opportunity to join our multidisciplinary team ...
-
Machine Learning Engineer, Nucleic Acids
2 weeks ago
Flagship Pioneering Cambridge, United StatesCompany Summary · Flagship Labs 97 Inc. (FL97) is a privately held, early-stage company pioneering the application of artificial intelligence to transform all science. Our Physical Sciences effort is developing a novel AI and data-driven approach to materials discovery and devel ...
-
Genomic Data Coordinator
3 hours ago
Biogen Cambridge, United States Full timeAbout This Role · In Biogen's Translational Sciences group, we leverage cutting-edge data and insights from human genetics and genomics, multi-omics, disease biology, and real-world patient and population cohorts to identify, validate, and prioritize novel drug targets, and to a ...
-
KCA Postdoctoral Fellow
3 weeks ago
Tempus AI Boston, United States Full timePassionate about precision medicine and advancing the healthcare industry? · Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evid ...
-
Research Technician II
2 weeks ago
Partners Healthcare System Charlestown, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: · A laboratory research technician position is available in Dr. Alexandra-Chloé Villani research at the MGH Center for Immunology and Inflammatory Diseases (CIID), where she also directs the Single Cell Genomics Research Program. Dr. Villani l ...
Senior/Principal Computational Biologist - Boston, United States - Asimov
Description
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We are searching for a Senior or Principal Computational Biologist with an extensive track record of developing innovative approaches that utilize mechanistic models, machine learning, omics, deep learning, and AI (e.g. LLMs). At Asimov, predictive modeling and simulation are core to our platform. We genetically engineer living cells and refine our designs using an ever-expanding suite of computational design methodologies and sophisticated analysis of multiomics data. The ideal candidate is motivated by designing complex cellular systems, distilling insight from large biological datasets, and producing novel tools to be used by others. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the foundation for engineering biology.
About the Role:
About You:
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Senior/Principal Computational Biologist professionals in Boston
-
Bryan Paul
Sr Cybersecurity Professional
-
Ronit Nossenson
Senior Director, Site Reliability Engineering
-
Samarth Kanodia
Computer Science Student
-
Zhongfa Yang
Senior Computational Scientist Bioinformatician