Senior Associate Scientist - Woburn, United States - Tiba Biotech LLC

Description

Job Description

Job Description

Description

Tiba Biotech is a preclinical stage biotechnology startup that emerged from government-funded RNA vaccine research at MIT in 2018. Our core technology is a class of customized dendrimer molecules that have unique and adaptable RNA encapsulation and cellular delivery properties. Founded by an accomplished team of scientists and entrepreneurs, we are a fast-paced, young company that is actively seeking to grow our team and expand our scientific portfolio of nucleic acid delivery technologies to new vaccine and therapeutics applications. We are seeking a Senior Associate Scientist with a strong background in molecular biology. The successful candidate will be responsible for designing, producing, and testing RNA constructs for various experimental vaccine and therapeutic applications both in vitro and in vivo. Experience with bacterial cloning, RNA handling (Extraction or In Vitro Transcription Synthesis), enzymatic assays, and immunoassays (ELISAs, Western Blots, etc) are required for this role. Experience with animal models (murine and other), Flow Cytometry, and a history of publications are preferred, but not required. He or she must have strong scientific communication, the ability to independently design and execute research projects, and present results in the form of detailed lab notebook entries, reports, and interface with a multidisciplinary team, including chemists and biologists in a fast-paced startup environment.

Responsibilities

• Independently develop RNA constructs utilizing Tiba's RNABL delivery platform for vaccine and therapeutic applications
• Evaluate antigen-encoding nucleic acid vectors in vitro and characterize immune responses in mice by ELISA and T cell assay
• Design and execute standard molecular biology assays and methods (bacterial cloning, PCR, ELISA, Western blot, nucleic acid electrophoresis)
• Prepare SOPs and guidelines for new experimental methods
• Maintain detailed recordkeeping in company's electronic lab notebook
• Assist with general laboratory maintenance and managing supply of reagents and consumables
• Participate in group meetings and contribute to publications and grants

Qualifications

• M.S. in Biology, Molecular Biology, Biochemistry or related field with 1-3 years of experience in laboratory setting
• B.S in Biology, Molecular Biology, Biochemistry or related field with 3-5 years of experience in laboratory setting
• Strong organizational skills, ability to prioritize tasks, and manage time independently
• Proficiency with software for sequence/data analysis (Excel, GraphPad Prism, SnapGene or equivalent)
• Ability to work collaboratively within group as well as within interdisciplinary teams
• Effective English verbal and written communication skills

Benefits

• Opportunity to participate in company stock option plan
• Health, Dental, Vision, STD/LTD, Accident and Critical Illness Insurance
• 401(k) Retirement Plan with company matching
• Company-provided Life and AD&D Insurance
• Company-sponsored HSA and FSA Plans offered
• Employee Assistance and Wellbeing Program
• Commuter Benefits Program

Compensation

• $75,000-$100,000 per year, commensurate on education and experience

Company DescriptionTiba Biotech is a preclinical stage biotechnology startup that emerged from government-funded RNA vaccine research at MIT in 2018. Our core technology is a class of customized dendrimer molecules that have unique and adaptable RNA encapsulation and cellular delivery properties. Founded by an accomplished team of scientists and entrepreneurs, we are a fast-paced, young company that is actively seeking to grow our team and expand our scientific portfolio of nucleic acid delivery technologies to new medical applications.

Company Description

Tiba Biotech is a preclinical stage biotechnology startup that emerged from government-funded RNA vaccine research at MIT in 2018. Our core technology is a class of customized dendrimer molecules that have unique and adaptable RNA encapsulation and cellular delivery properties. Founded by an accomplished team of scientists and entrepreneurs, we are a fast-paced, young company that is actively seeking to grow our team and expand our scientific portfolio of nucleic acid delivery technologies to new medical applications.