- Innate immunity
- Endogenous retroviruses
- Retrotransposons
- Chromatin and epigenetics
- Promotion of cancer cell death
- For more information about the lab's research, please visit: or contact Dr. Longworth at
- Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
- Designing and conducting experiments; analyzing results
- Writing scientific manuscripts
- Writing fellowships
- Attending national and international scientific conferences
- PhD or MD/PhD required
- MD with relevant laboratory experience may substitute for PhD
- English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status
- Previous experience in a research or academic setting. Graduate student experience meets this requirement.
- Scientific writing experience
- Experience with any of the following:
- Retrotransposable elements
- Innate immune signaling
- CUT&RUN, RNA-seq, scRNA-seq, chromatin confirmation capture techniques
- CRISPR/ Cas9
- Ability to perform work in a stationary position for extended periods
- Ability to operate a computer and other office equipment
- Ability to communicate and exchange accurate information
- Ability to distinguish color
- Manual dexterity to handle specimens and repair equipment
- Ability to lift and transport equipment or specimens weighing up to 20 pounds
- May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.
- PPE per institutional requirements; may vary by laboratory
- CV
- Short description of thesis work (1-2 paragraphs)
- List of 3 references
- All application materials should be submitted directly via email to Michelle Longworth at
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Postdoctoral Fellow - Cleveland, United States - Cleveland Clinic
Description
Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply.This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting.
This position will be located at the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada.The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal.
This program is expected to be completed within 5 years.
LINE-1 retrotransposons and endogenous retroviruses comprise a large portion of the human genome, and their upregulation can lead to induction of innate immune signaling pathways.
Our objective is to understand how genome organizing proteins regulate this signaling, with the ultimate goal of identifying new pathways that can be targeted to promote cancer cell death and/or prevent autoinflammatory disease pathogenesis.
Our lab is R01 funded, we have been very successful in obtaining federal and private, independent funding for postdocs, and we are excited to add passionate, motivated and creative scientists to our group.
Principal Investigator:
Michelle Longworth, PhD
Lerner Research Institute Department:
Inflammation & Immunity
Lab Research Topics:
Job Responsibilities:
Education:
Languages:
Work Experience:
Additional Preferred Qualities:
Physical Requirements:
Personal Protective Equipment:
Preferred Application Materials:
Keywords:
Postdoc, Research, LRI, Immunology, Cancer, Virus, Retrovirus, Epigenetics, Chromatin, Innate immunity, Signaling
Pay Range
Minimum hourly:
$0.01
Maximum hourly:
$333,340.26
The pay range displayed on this job posting reflects the anticipated range for new hires.
While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary.
A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education.
This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.
