- Lead biological engineering projects focused on development of next-generation viral vectors
- Create and deploy high throughput cellular and molecular screening systems to identify novel capsids
- Develop and implement quantitative in vitro cellular and molecular assays to characterize lead candidates
- Assess candidates' pharmacological properties in vivo
- Maintain accurate, detailed, and timely records
- Perform data analysis and review, ensuring accuracy and completeness
- Participate in cross-disciplinary mentoring and training within the RDL NH team
- Present results to the biologics team, Insmed research department, and external scientific community, as needed
- Assist with coordination and day-to-day management of RDL NH site operationsPosition Requirements (Required and/or Preferred Skills, Experience and Education):
- PhD or MS with equivalent experience in cell biology, virology, molecular biology, bioengineering, or related field. Position level commensurate with experience.
- Deep expertise with viruses or viral vectors required, experience with AAV vectors strongly preferred
- Familiarity with viral vector engineering for gene therapy applications strongly preferred
- Hands on experience with transfection, transduction, viral purification, ultracentrifugation, viral titering, qPCR, ddPCR required
- Experience with molecular biology and recombinant DNA technology required, experience with viral vector library construction and production strongly preferred
- Hands on experience with mammalian cell lines and primary cells required
- Hands-on experience with flow cytometry, neutralization assays and other cell-based functional assays preferred
- Hands-on in vivo model experience preferred, if no experience, must be open to learning
- Proven track record in experimental methods development, including experimental design, execution, and data analysis and interpretation
- Strong analytical and problem-solving skills
Salary Range
Insmed takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees.
The base salary range for this job is from $89,000.00 to $119,267.00 per year
Compensation & BenefitsWe're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:
- Flexible approach to where and how we work
- Competitive compensation package including bonus.
- Stock options and RSU awards
- Employee stock purchase plan
- 401(k) plan with company match
- Professional Judgment Vacation Policy
- 11 paid holidays per year and Winter Break (typically between Christmas and New Year's Day). ADDITIONAL U.S. BENEFITS:
- Medical, dental, and vision plans
- Company-provided short- and long-term disability plans
- Company-provided life insurance
- Unique offerings of pet, legal, and supplemental life insurance
- Flexible spending accounts for medical and dependent care
- Accident and Hospital Indemnity plans
- Supplemental AD&D
- Employee Assistance Program (EAP)
- Mental Health on-line digital resource
- On-site, no-cost fitness center at our U.S. headquarters
- Paid time off to volunteer
Additional InformationInsmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.
Applications are accepted until the position is filled.
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Scientist - West Lebanon, United States - Insmed Incorporated
Description
Company Description
Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.
Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.
Recognitions
Named Science's Top Employer in 2021, 2022, and 2023 Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we were named the No. 1 company to work for in the biopharma industry in Science's Top Employers Survey for two years in a row. A Certified Great Place to Work We believe our company is truly special, and our employees agree. In July 2023, we became Great Place to Work-certified in the U.S. for the third year in a row. We are also honored to have been listed on the Best Workplaces in BiopharmaTM, Best Workplaces in New YorkTM, and Best Workplaces for MillennialsTM lists.
Overview
Insmed is seeking a skilled and creative biologist, virologist, or bioengineer to lead discovery and engineering campaigns focused on next-generation gene therapies for rare diseases. The successful candidate will operate within a cross-disciplinary team of experimental and computational scientists, taking primary responsibility for wet lab elements of programs.
• This is not a supervisory position
• This role oversees vendors and/or contractors
Responsibilities
Responsibilities (Essential Role Responsibilities):
