Sr Scientist - St Louis, United States - RPM ReSearch

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    Description
  • Senior Scientist/ Principal Investigator -Oligonucleotide Bioanalysis
  • We are inviting an accomplished scientist to join our growing drug discovery DMPK and Small Molecule Bioanalysis team.
  • The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology, and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
  • Independently designs and implements novel Bio/-analytical methods to support research projects relating to the development of antisense or siRNA Oligonucleotide based therapeutics.
  • Act as an oligonucleotide bio/-analytical SME and work cross-functionally to build internal capabilities.
  • BS or equivalent degree in Chemistry, Biochemistry, or related field, and greater than 15 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management or,
  • Proven track record of scientific contributions in the development of oligonucleotide analytical and bioanalytical methods to support oligonucleotide delivery platform development.
  • Demonstrates inter-disciplinary knowledge of drug discovery (in vitro/ in vivo pharmacology, ADME, PK/PD, translational research, and toxicology)