Clinical Pharmacology Director - Boston - Vertex Pharmaceuticals

    Vertex Pharmaceuticals
    Vertex Pharmaceuticals Boston

    1 hour ago

    Description

    Job Description

    General Summary:

    The Clinical Pharmacology Director leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the development of clinical pharmacology plans; assists in departmental management through program reviews and collaborative decision-making; supervises asset leads, provides career development; routinely co-leads cross-functional efforts and leads department initiatives.

    Key Duties and Responsibilities:

    • Responsible for the application of clinical quantitative pharmacology strategy to support the immunology portfolio.
    • Guides metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues.
    • Co-leads or serves on cross-functional committees and/or contributes to or leads departmental initiatives
    • Creates protocol concepts and guides protocol start-up including site initiations and investigator meetings
    • Oversees and contributes to regulatory and safety documents
    • Contributes to clinical pharmacology summary documents
    • Guides PK analyses
    • Performs PK/PD or exploratory analyses and guides PK/PD modeling or simulations as appropriate
    • Provides mentorship to staff
    • Assists in recruitment and hiring

    Knowledge and Skills:

    • Strong foundational knowledge in the clinical pharmacology of biologics, small molecules, and/or other drug modalities
    • Working experience of Immunology and Autoimmune diseases therapeutic area or relevant disease knowledge
    • Experience in executing quantitative clinical pharmacology to derive decisions. Hands-on expertise in data analysis using industry-standard tools such as Phoenix WinNonlin, R, and NONMEM.
    • Experience of interaction with healthy authorities
    • Effective leadership skills to drive performance and provide career development opportunities to staff
    • Critical thinking skills, with keen scientific and development judgment
    • Experience planning and executing Clinical Development Plans for new clinical entities particularly as it applies to the discipline of Clinical Pharmacology
    • Experience conducting and supervising clinical studies such as drug-drug interaction, special population or bioavailability
    • Experience with a range of clinical studies including first-in-human, proof-of-concept and registrational studies
    • Experience contributing to clinical and regulatory documents such as the Investigator's Brochure and contributing to regulatory correspondence
    • Experience working on teams and in a matrix environment

    Education and Experience:

    • Ph.D. or Pharm D (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 10+ years of relevant post-doctoral employment experience, or
    • Masters Degree (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 15+ years of relevant employment experience
    • Typically requires 3 years of supervisory/management experience

    #LI-KM4

    Pay Range:

    $200,000 - $300,000

    Disclosure Statement:

    The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

    At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

    Flex Designation:

    Remote-Eligible

    Flex Eligibility Status:

    In this Remote-Eligible role, you can choose to be designated as:
    1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
    2. Hybrid: work remotely up to two days per week; or select
    3. On-Site: work five days per week on-site with ad hoc flexibility.

    Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

    #LI-Remote

    Company Information

    Vertex is a global biotechnology company that invests in scientific innovation.

    Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

    Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    Job Description · General Summary: · The Clinical Pharmacology Director leads strategic, scientific, and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the develop ...

    Boston, MA

    1 day ago

  • Work in company

    Senior Director, Pharmacology

    Only for registered members

    We're seeking an experienced Senior Director of Pharmacology to join our Development team. You will lead our pharmacology efforts in supporting late-stage drug development programs across multiple therapeutic areas. · Lead the pharmacology team in supporting late-stage drug devel ...

    Boston $293,000 - $403,000 (USD) Full time

    1 month ago

  • Work in company

    Director Clinical Pharmacology

    Only for registered members

    This rapidly growing biotech organization is hiring for a Director Clinical Pharmacology who will serve as the Clinical Pharmacology expert responsible for advancing the team's early-stage assets. · Lead clinical pharmacology for assigned programs, · drive dose selection, PK/PD a ...

    Boston

    1 month ago

  • Work in company

    Clinical Pharmacology Director

    Only for registered members

    Job Description · General Summary: · The Clinical Pharmacology Director leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the developm ...

    Boston $200,000 - $300,000 (USD) Full time

    2 weeks ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    Job Description · General Summary: · The Clinical Pharmacology Director leads strategic, scientific, and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the develop ...

    Boston $200,000 - $300,000 (USD)

    1 day ago

  • Work in company

    Clinical Pharmacology Director

    Only for registered members

    The Clinical Pharmacology Director leads strategic scientific operational aspects at a program level. · This role represents the department on strategic operational cross-functional program teams · and will be responsible for developing clinical pharmacology plans assisting in d ...

    Boston $200,000 - $300,000 (USD) Full time

    2 weeks ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    Job Description · General Summary: · The Clinical Pharmacology Director leads strategic, scientific, and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the develop ...

    Boston $200,000 - $300,000 (USD) Full time

    1 day ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I subm ...

    Boston, MA

    1 week ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use.  I further attest that all information I sub ...

    Boston $174,500 - $274,230 (USD) Full time

    2 weeks ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I subm ...

    Boston $174,500 - $274,230 (USD)

    1 week ago

  • Work in company

    Clinical Pharmacology Director

    Only for registered members

    Job Description · General Summary: · The Clinical Pharmacology Director leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the developm ...

    Boston $200,000 - $300,000 (USD)

    2 weeks ago

  • Work in company

    Clinical Pharmacology Director

    Only for registered members

    +h2>Job summary · The Clinical Pharmacology Director leads strategic scientific operational aspects at a program level. · Guides metabolic co-dosing drug-drug interaction issues collaborating closely with cross-functional colleagues · Co-leads or serves on cross-functional commit ...

    Boston, MA

    2 weeks ago

  • Work in company

    Director, Clinical pharmacology

    Only for registered members

    Join Hemab on an exciting journey to build the ultimate clotting company. We focus on addressing high unmet needs of patients suffering from rare bleeding and thrombotic disorders. · Plan manage and deliver clinical pharmacology strategy through execution of pharmacokinetics PK p ...

    Cambridge

    1 month ago

  • Work in company

    Director, Clinical pharmacology

    Only for registered members

    We are seeking an experienced Director of Clinical Pharmacology to join our team at Hemab. · Plan, manage and deliver the clinical pharmacology strategy through execution of pharmacokinetics (PK), pharmacodynamics (PD), PK-PD modeling and pharmacometrics modules for clinical stag ...

    Cambridge

    1 month ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    We are seeking a Senior Director, Clinical Pharmacology to join our team at Kailera Therapeutics. The successful candidate will be responsible for designing and executing clinical pharmacology studies to support the development of novel therapies for obesity-related diseases. · T ...

    Greater Boston

    1 month ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    Job Description · General Summary: · The Senior Director, Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. The Senior Director, Clinical Pharmacology will also manage the scientific functions and coordinate the activities of the Clinical Pharma ...

    Boston, MA $180,000 - $260,000 (USD) per year

    5 days ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    +The Senior Director, Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. · +Serves as the disease area leader and is responsible for global clinical pharmacology strategy and plans. · ...

    Boston, MA

    1 month ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    The Senior Director Clinical Pharmacology will provide strategic leadership in clinical pharmacology pharmacokinetics and modeling simulation to support Korsanas programs across the drug development lifecycle. · Drive and execute clinical pharmacology strategies across developmen ...

    Boston

    2 weeks ago

  • Work in company

    Director, Clinical Pharmacology

    Only for registered members

    Job summary · The Role · The Director will bring strong technical expertise in clinical pharmacology. ...

    Cambridge $167,000 - $300,700 (USD)

    1 month ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    The Senior Director, Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. The Senior Director, Clinical Pharmacology will also manage the scientific functions and coordinate the activities of the Clinical Pharmacology function in collaboration with ...

    Boston $232,000 - $348,000 (USD) Full time

    1 month ago

  • Work in company

    Senior Director, Clinical Pharmacology

    Only for registered members

    At Kailera, we are bold, authentic and committed to our mission of developing therapies that give people the power to transform their lives and elevate their overall health. Rooted in an entrepreneurial spirit and a team-oriented culture, we are working together to advance Kailer ...

    Boston $241,000 - $295,000 (USD)

    2 weeks ago

Jobs
>
Boston