- D. in Neuroscience, Biochemistry and Molecular Biology, or Related Discipline.
- Skilled in conventional molecular methods such as quantitative methods for qualitative and quantitative analysis of gene expression (qPCR, ddPCR, Southern, Northern and Western blotting), gene cloning;
- Experience culturing neurogenic cell lines;
- Some experience in culturing and differentiation of human iPSC is desirable, but not an absolute prerequisite;
- Analogously for generation of key sequences for therapeutic oligonucleic acids; understanding aspects of oligonucleic acid synthesis and purification;
- Some experience with animal therapy trials (mainly mice), including drug dosing by various routes of administration (SC, IV, IP, oral gavage, IT);
- Behavioral analysis of mouse models;
- Ability to compile and analyze data using standard statistical methods.
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Post Doctoral Associate
1 week ago
University of Massachusetts Worcester, United States Full timeOverview · JOB DESCRIPTION: The Department of Biochemistry and Molecular Pharmacology invites applications or a postdoctoral position in the laboratory of Dr. William Kobertz. · This position is for an applicant who will use cellular imaging and electrophysiological techniques t ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · Post-doctoral positions are available for a Bill & Melinda Gates Foundation funded research project. The research focuses on determining the mechanism of recombinant adeno-associated virus (rAAV) vector DNA persistent gene expression. The 3yr project will be supervised ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesThe University of Massachusetts Chan Medical School · Application Deadline: Open Until Filled · Job Description · Postdoctoral Associate in Molecular Neurobiology · A postdoctoral associate position is available in the Richter Lab for a highly motivated candidate with a PhD in mo ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · Postdoctoral Associate, Lab of Viral Replication, Pathogenesis, and Immunity, UMass Medical School · Candidates are invited to apply for a post-doctoral position to study pathogenic viruses, including SARS-CoV-2, Ebola virus, and HIV-1. Research topics include basic me ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · The University of Massachusetts Chan Medical School · * Application Deadline: Open Until Filled · Job Description · Postdoctoral Associate in Molecular Neurobiology · A postdoctoral associate position is available in the Richter Lab for a highly motivated candidate wit ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesPostdoctoral Associate, Lab of Viral Replication, Pathogenesis, and Immunity, UMass Medical School · Candidates are invited to apply for a post-doctoral position to study pathogenic viruses, including SARS-CoV-2, Ebola virus, and HIV-1. Research topics include basic mechanisms of ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesWe are inviting applications for postdoctoral positions to pursue multiple research topics that encompass gene therapy using AAV vectors, RNA therapy, virology, and AAV vector development. · Applicants should have a PhD degree or an MD in relevant areas such as Molecular Biology, ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · The Horae Gene Therapy Center of the University of Massachusetts Chan Medical School invites applications for a postdoctoral researcher position to develop AAV-based gene therapy technologies using genome editing and RNA-based methods. · Applicants should have a PhD de ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesA Postdoctoral Fellow position is immediately available in the laboratory of Dr. Fen-Biao Gao at the University of Massachusetts Chan Medical School to study mouse models of fronototemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) (please see our recent papers: ). C ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · Research focus and environment: · Three postdoctoral scholar positions are immediately available in the Zhong lab in the Horae Gene Therapy Center (GTC) and RNA Therapeutics Institute (RTI) at the University of Massachusetts Chan Medical School. The GTC and RTI are hig ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesWe are inviting applications for postdoctoral positions to pursue multiple research topics that encompass: gene therapy using AAV vectors, RNA therapy, gene editing, immunology, virology, and AAV vector development. · Applicants should have a PhD degree or an MD with post-gradua ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesThe Horae Gene Therapy Center of the University of Massachusetts Chan Medical School invites applications for a postdoctoral researcher position to develop AAV-based gene therapy technologies using genome editing and RNA-based methods. · Applicants should have a PhD degree in rel ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesWe are recruiting a postdoctoral researcher with a focus on artificial intelligence (AI) for health informatics. The successful applicant will have a Ph.D. in biomedical informatics, computer science or a related field. Working experience with electronic health records (EHRs) dat ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · We are inviting applications for postdoctoral positions to pursue multiple research topics that encompass: gene therapy using AAV vectors, RNA therapy, gene editing, immunology, virology, and AAV vector development. · Applicants should have a PhD degree or an MD with p ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesThe University of Massachusetts Medical School · Application Deadline: Open Until Filled · Job Description · Postdoctoral Associate in the Ceol lab. · A postdoctoral position is available in the laboratory of Dr. Craig Ceol in the Program in Molecular Medicine and Department of M ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · The newly established Moore lab is looking for highly motivated post-doctoral fellows to be founding members of our team. We study gene regulation and its role in human disease by interpreting large scale multi-omic datasets using machine learning approaches. Ideal can ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · A Postdoctoral Fellow position is immediately available in the laboratory of Dr. Fen-Biao Gao at the University of Massachusetts Chan Medical School to study mouse models of fronototemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) (please see our recent p ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesThe Brown Lab at the University of Massachusetts Chan Medical School () has immediate post-doctoral positions open in gene modulation therapy for ALS and related neurodegenerative diseases. As one component of a new "Accelerator Initiative"( ), we are pursuing several approaches ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesA two year post-doctoral position is available to work on project involving molecular cloning and cellular biology for AAV production using Sf9 cell system. The candidate will be part of a collaboration between Umass Chan Medical School in Worcester, MA and AbbVie, a biopharmaceu ...
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Post Doctoral Associate
2 weeks ago
University of Massachusetts Medical School Worcester, United StatesOverview · We are recruiting a postdoctoral researcher with a focus on artificial intelligence (AI) for health informatics. The successful applicant will have a Ph.D. in biomedical informatics, computer science or a related field. Working experience with electronic health records ...
Post Doctoral Associate - Worcester, United States - University of Massachusetts Medical School
Description
OverviewThe Brown Lab at the University of Massachusetts Chan Medical School ) has immediate post-doctoral positions open in gene modulation therapy for ALS and related neurodegenerative diseases.
As one component of a new "Accelerator Initiative"( $15-million-to-advance-als-neuroscience-research/), we are pursuing several approaches to modifying adverse gene variants that are implicated in both familial and sporadic ALS.
These include gene suppression (e.g. antisense oligonucleotides activating RNAse H), gene augmentation (small activating RNAs), and gene editing (e.g. gene editing, base editing, splice modification).This program entails a productive, close collaboration with Jonathan Watts and Anastasia Khvorova in the UMass Chan RNA Therapeutics Institute.
This program is built upon our recent pilot human studies in suppression of two ALS genes, SOD1 (PMID and C9orf72 (PMID Our explicit goal is to transition rapidly from pre-clinical studies to pilot human studies for several other ALS genes.It is our hope that the approaches developed in this program will be broadly applicable to a wide variety of human disorders.
Preferred qualifications:
UMass Chan offers strong support and mentoring, a collaborative research environment, a competitive salary with benefits, and visa sponsorship available.
Interested applicants should submit the following materials via email to Susan Jacobs ) and Robert Brown ): a cover letter describing current research activities and your interest in this position, a current CV (including publications), and contact information for three references, one of which should be your Ph.
Responsibilities
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Post Doctoral Associate professionals in Worcester
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yuehe ding
CRISPR, Aging, RNAi, LC-MS/MS, Proteomics, NGS