Senior Scientist/Principal Scientist, Quantitative Pharmacology - Somerset
Only for registered members Somerset, United States
2 weeks ago
* This salary range is an estimation made by beBee
Job summary
Legend Biotech is seeking a Senior Scientist/Principal Scientist, Quantitative Pharmacology to lead modeling and simulation efforts in support of gene and cell therapy products.
Responsibilities
- Lead QSP and popPK modeling activities across preclinical and clinical development stages.
- Play a pivotal role in shaping clinical pharmacology strategies, supporting regulatory submissions, and driving innovation in model-informed drug development (MIDD).
- Develop and apply mechanistic models to understand disease pathways, drug mechanisms, and patient variability.
- Conduct simulations to support dose selection, trial design, and exposure-response analyses.
- Collaborate cross-functionally with R&D, clinical, regulatory, and biostatistics teams.
- Author and review clinical pharmacology sections of regulatory documents (e.g., INDs, NDAs).
- Contribute to scientific publications and conference presentations.
Job description
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