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    Scientist - Berkeley, United States - Theery

    Default job background
    Pharmaceutical / Bio-tech
    Description

    Cell Engineering Scientist

    Requirements/Responsibilities:

    • Expert-level knowledge in various cell engineering methods, including experience with iPSCs and differentiated cells.
    • Deep understanding of advanced techniques such as epigenetic targeting, global editing, CRISPRa, CRISPRi, and RNA-based reprogramming
    • Well-versed in thinking about complex, cutting-edge methods to target cell differentiation using cell engineering tools.
    • You will lead projects designing vectors for gene expression or silencing in stem cells to create specific cell types.
    • You will work with our computational team to analyze single-cell RNA-seq data to target genes effectively and collaborate with our organoid team to develop organoid models using reprogrammed cells.
    • Transfecting (using viral or non-viral vectors) different cell types and ideally have run larger gene editing and/or transgene expression screens before.
    • Experience with different assays that could be used as a functional readout such as flow cytometry, immunofluorescence, and RNAseq. E
    • Experience with computational tools to analyze data is a big plus.

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