Scientist/Sr Scientist, Research Physiology - San Francisco, CA, United States - California Life Company

Description

Who we are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico's highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position description:

Calico seeks an outstanding and innovative scientist to join our Research Physiology group. The Research Physiology group is responsible for in vivo basic research and developing animal models and adapting technologies to study aging and aging-related diseases. Research will be conducted in close collaboration with our Principal Investigator-led research labs whose interests span across biological systems, including the respiratory, cardiovascular, nervous, and immune systems. This position requires extensive hands-on experience in in vivo physiology in rodents and the willingness and flexibility to collaborate with others on different projects at the same time. Candidates with experience with multiple experimental approaches and/or organ systems are particularly encouraged to apply. Calico provides a stimulating and collaborative working environment focused on fundamental discovery research and a commitment to translate scientific advances to realize their therapeutic potential.

Position requirements:

Ph.D. degree in Biology, Physiology, Medicine or related field with 0-8 years of relevant in vivo experience

Experience with complex in vivo procedures in rodents (survival surgeries, gene delivery, drug delivery)

Experience with non-invasive and invasive techniques to characterize physiological processes in vivo (implantable telemetry, functional and behavioral assays, in vivo imaging, histological and biochemical endpoints)

Good understanding of genetic and pharmacological approaches to modulate pathways of interest

Excellent writing, presentation, and communication skills

Ability to work collaboratively with multiple teams

Ability to work on-site for at least four days per week

Nice to have:

Experience with viral and non-viral gene delivery in rodents

Experience with neurodegenerative disease models

Experience with pulmonary disease models

Experience with immunological disease models

Background in aging research

Experience mentoring or supervising junior researchers

The estimated base salary range for this role is $127,000 - $172,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.