- Applicants must have an MD, Ph.
- Previous experience in a wet lab including work with cell cultures and animal models is required.
- Candidates should be capable of designing and carrying out high-level, complex research experiments independently.
- Expertise in lab techniques including, but not limited to, immunofluorescence, western blotting, ELISA, qPCR, qRT-PCR, flow cytometry, protein biochemistry, glycobiology, etc.
- Applicants with a good track record of publication are desirable, along with effective communication skills and scientific writing skills.
- Ability to train and mentor laboratory staff and graduate students.
- Writing and publishing scientific material, including manuscripts.
- Presenting research at regional, national, and international conferences.
- Contributing to grant submissions for external funding.
- Up to 5 years of salary support, to be renewed annually based on productivity
- Strong mentorship to support career development toward academia or industry jobs
- State-of-the-art laboratories and core facilities
- Possible affiliation with The Ohio State University College of Medicine
- Collaborative initiatives with clinical faculty
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Post Doctoral Scientist - Columbus, United States - Nationwide Children's Hospital
Description
OverviewEMPLOYER:
Gene Therapy LaboratoryAbigail Wexner Research Institute, Nationwide Children's Hospital (NCH).
LOCATION:
Columbus, Ohio,
USA
POSITION TYPE:
Full-time
PREFERRED START DATE:
April 2024
DISCIPLINE:
Gene Therapy
ORGANIZATION TYPE:
Non-profit
RESEARCH DESCRIPTION:
Our group is focused on developing novel gene therapy treatments for neuromuscular disorders and lysosomal storage disorders.
We have recently developed and tested a novel gene therapy in patients with Duchenne Muscular Dystrophy and are currently developing treatments for Limb Girdle Muscular Dystrophy Type R9, GNE myopathy, and Lysosomal Acid Lipase Deficiency.
This research involves basic and proof of concept studies in animal models for these diseases, as well as safety studies, with the goal of developing IND approvals for the testing of therapies in clinical trials.
We collaborate with a team of other laboratories in Center for Gene Therapy and at Ohio State University to accomplish these goals.
The successful candidate will have an excellent foundation in molecular and cellular biology and also in molecular and cellular pathology.
We are particularly interested in candidates who also have experience analyzing animal models of disease and who understand the concepts relevant to design of disease therapies for muscle, liver, and/or brain disorders.
As our lab focuses on diseases and therapies involving glycosylation, experience in glycobiology would be a major plus. Expertise in skeletal muscle or cardiac physiology, or AAV biology, would also be a major plus.To apply, please submit curriculum vitae, a cover letter indicating areas of expertise and a detailed statement of research interests and scientific accomplishments, and a list of 3 references.
The selected candidate will be professional, self-motivated, and dedicated, with strong communication and interpersonal skills that will fit with our highly collaborative team.
You will have many opportunities to learn new skill sets, present your work, develop professionally, and contribute to identifying new therapies for children with genetic disorders.
This position offers candidates to be involved in basic research and translation to the clinicQUALIFICATIONS:
COMPETENCIES, KNOWLEDGE, SKILLS, AND ABILITIES:
We can offer potential candidates:
