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    Post-doctoral fellow - New York City, United States - Sia Lab

    Sia Lab
    Sia Lab New York City, United States

    1 month ago

    Default job background
    Full time
    Description


    We are seeking a highly motivated post-doctoral fellow to work on an externally-funded project aimed at characterizing novel immunocompetent mouse models of cholangiocarcinoma driven by mutant KRASG12D in combination with different co-occurring genetic alterations.

    The overarching goal of the study is to understand how oncogenic KRAS cooperates with other drivers to shape the immune microenvironment and response to therapies.

    The main aspects of the research include: i) the generation of gene delivery-based mouse models; ii) molecular and immunophenotypic analyses of murine tumors; iii) generation and maintenance of organoid cultures; and iv) in vitro and in vivo drug screenings.

    The responsibilities include generation of the mouse models above mentioned, characterization of resulting tumor sand establishment of organoids for drug screening.

    In addition, data analysis and results interpretation are expected.

    Educational and other Requirements for the position: PhD in cancer biology or related field


    Experience Required:
    experience with animal work (at least 1 year)
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