Biomarker Therapeutic Area Lead - UnitedStates, United States - Novartis

Description

Hybrid

About the role:
As an Immunology Therapeutic Area Biomarker Lead (TABL) you will lead disease area biomarker matrix teams and be accountable for the delivery of "fit for purpose" exploratory biomarker strategies across multiple programs in early and late clinical stages. In late phase particularly, you'll be expected to assume the overall accountability for the biomarker strategy for at least one of our portfolio assets. You will be a core member of Project teams, involved in Global Biomarker and Diagnostic Teams, engaged in Translational Data Science teams, and provide therapeutic area line strategic, scientific and tactical input.

As a TABL you will lead efforts to identify, develop, and drive disease, mechanistic and compound biology that serves the precision medicine hypotheses for the multi-indication portfolio.

Your key responsibilities:

• Delivering therapeutic area, as well as clinical project, "fit for purpose" exploratory biomarker strategies within our Immunology General Medicine disease indications and in close collaboration with research, clinical development and commercial functions.

• Leading a dedicated matrixed group of biomarker subject matter experts and project team representatives to develop and contribute to clinical project strategies, plans and timelines in partnership with line function leaders.

• Leading overarching asset related biomarker strategies enabling the delivery of late phase assets and respective launch.

• Representing BMD on early and late Disease Area Decision Boards to identify, develop, and drive disease and compound mechanistic biology, clinical decision-making exploratory biomarkers and precision medicine hypotheses for the portfolio.

• Co-leading strategic translational data working groups centered on integrating and analyzing large-scale patient muti-modal data sets (omics, imaging, digital, etc.) to identify new indications and endpoints, enable early and late phase data delivery to support decision making, and identify potential responder patient subpopulations.

• Providing thought leadership with other BMD TABLs to identify synergies and drive innovation across our large and diverse clinical portfolio in General Medicine.

• Representing BMD line functions in Therapeutic Area Line Function committees for clinical protocol development.

• Implementing strategies in close collaboration with the BMD global organization which includes over 100 associates with expertise in all aspects of biomarker science i.e. genetics, genomics, molecular and cellular, digital devices, imaging and data sciences.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Role Requirements

Essential Requirements:

• MD, MD/PhD, or PhD degree required, PhD/postdoc or equivalent level research

• 5+ years professional experience

• Industry experience preferred

• Deep understanding of clinical disease that can be applied to questions of biomarker development, diagnosis, and treatment monitoring

• Clinical and/or biological expertise in immunology or related field

• Relevant expertise utilizing biomarkers for clinical decision-making including pharmacodynamics, clinical efficacy, disease deconvolution, response characterization, patient stratification and/or precision medicine

• Evidence of interpreting and disseminating omics related findings, e.g. genetics, genomics, proteomics, with relevant application to clinical decision making while partnering with key stakeholders from research, data sciences and clinical development.

• Proven success in leading and partnering in multidisciplinary matrix teams across Pharma/biotech (clinical research through healthcare applications), academic institutions, or commercial business functions

Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us Learn more here:

You'll receive:
You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.

Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $183,000 – $274,000/year; however, while salary ranges are effective from 1/1/23 through 12/31/23, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

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