Staff Machine Learning Engineer, Oncology foundation Model - Chicago - Tempus

    Tempus
    Tempus Chicago

    14 hours ago

    $170,000 - $230,000 (USD) per year
    Description
    Passionate about precision medicine and advancing the healthcare industry?
    Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
    We are seeking an experienced and highly skilled Staff Machine Learning Engineer with deep expertise in large-scale multimodal model systems engineering to join our dynamic AI team. You will play a pivotal role in designing, building, and optimizing the foundational data infrastructure that powers Tempus's most advanced generative AI models. Your work will directly enable the training and deployment of robust, production-ready multimodal systems that analyze complex data types (like genomics, pathology images, radiology scans, and clinical notes) to improve patient care, optimize clinical workflows, and accelerate life-saving medical research. This is a critical, high-impact position for driving the practical application of cutting-edge AI to revolutionize healthcare.
    Focus:
    Your primary focus will be to architect, build, and maintain the critical data infrastructure supporting our large multimodal generative models. This includes managing the entire lifecycle of vast datasets - from ingestion and processing of diverse training data to the integration and retrieval of extensive knowledge sources used to augment model capabilities. You will be building the data backbone that enables our AI to learn from Tempus's rich real-world evidence.
    Key Responsibilities:
    As a technical leader in this space, you will be:
    • Architect and build sophisticated data processing workflows responsible for ingesting, processing, and preparing multimodal training data that seamlessly integrate with large-scale distributed ML training frameworks and infrastructure (GPU clusters).
    • Develop strategies for efficient, compliant data ingestion from diverse sources, including internal databases, third-party APIs, public biomedical datasets, and Tempus's proprietary data ecosystem.
    • Utilize, optimize, and contribute to frameworks specialized for large-scale ML data loading and streaming (e.g., MosaicML Streaming, Ray Data, HF Datasets).
    • Collaborate closely with infrastructure and platform teams to leverage and optimize cloud-native services (primarily GCP) for performance, cost-efficiency, and security.
    • Engineer efficient connectors and data loaders for accessing and processing information from diverse knowledge sources, such as knowledge graphs, internal structured databases, biomedical literature repositories (e.g., PubMed), and curated ontologies.
    • Optimize data storage for efficient large scale training training and knowledge access.
    • Orchestrate, monitor, and troubleshoot complex data workflows using tools like Airflow, Kubeflow Pipelines..
    • Establish robust monitoring, logging, and alerting systems for data pipeline health, data drift detection, and data quality assurance, providing feedback loops for continuous improvement.
    • Analyze and optimize data I/O performance bottlenecks considering storage systems, network bandwidth and compute resources.
    • Actively manage and seek optimizations for the costs associated with storing and processing massive datasets in the cloud.
    Required Skills and Experience:
    • Master's degree in Computer Science, Artificial Intelligence, Software Engineering, or a related field. A strong academic background with a focus on AI data engineering.
    • Proven track record (8+ years of industry experience) in designing, building, and operating large-scale data pipelines and infrastructure in a production environment.
    • Strong experience working with massive, heterogeneous datasets (TBs+) and modern distributed data processing tools and frameworks such as Apache Spark, Ray, or Dask.
    • Strong, hands-on experience with tools and libraries specifically designed for large-scale ML data handling, such as Hugging Face Datasets, MosaicML Streaming, or similar frameworks (e.g., WebDataset, Petastorm). Experience with MLOps tools and platforms (e.g., MLflow, Kubeflow, SageMaker Pipelines).
    • Understanding of the data challenges specific to training large models (Foundation Models, LLMs, Multimodal Models).
    • Proficiency in programming languages like Python and experience with modern distributed data processing tools and frameworks.
    • Leadership and collaboration:
      • Proven ability to bring thought leadership to the product and engineering teams, influencing technical direction and data strategy.
      • Experience mentoring junior engineers and collaborating effectively with cross-functional teams (Research Scientists, ML Engineers, Platform Engineers, Product Managers, Clinicians).
      • Excellent communication skills, capable of explaining complex technical concepts to diverse audiences.
      • Strong bias-to-action and ability to thrive in a fast-paced, dynamic research and development environment.
      • A pragmatic approach focused on delivering rapid, iterative, and measurable progress towards impactful goals.
    Preferred Qualifications:
    • Advanced degree (PhD) in Computer Science, Engineering, Bioinformatics, or a related field.
    • Contributions to relevant open-source projects.
    • Direct experience working with clinical or biological data (EHR, genomics, medical imaging).
    #LI-SH1
    New York Pay Range - $190,000 - $230,000 USD
    California Pay Range - $190,000 - $230,000 USD
    Illinois Pay Range - $170,000 - $210,000 USD
    Remote - USA Range - $170,000 - $210,000 USD
    The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
    Additionally, for remote roles open to individuals in unincorporated Los Angeles - including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
  • Work in company

    Lead Data Scientist (P4356)

    Only for registered members

    We are seeking an experienced Senior Data Scientist to serve as a Developer Advocate for our Foundation Models team. · Drive adoption of foundation models across business units through stakeholder engagement, · workshops and training sessions. · Create comprehensive user guides d ...

    Chicago, IL

    1 month ago

  • Work in company

    Remote Legal Expert - 42119

    Turing

    About Us: · Turing is one of the world's fastest-growing AI companies, pushing the boundaries of AI-assisted software development. Our mission is to empower the next generation of AI systems to reason about and work with real-world software repositories. You'll be working at the ...

    Chicago

    8 hours ago

  • Work in company

    Volunteer / Intern High School Mentor Liaison

    Only for registered members

    · Company Description · The Aparecio Foundation is a nonprofit organization that was designed as an economic development strategy to lift women out of poverty and as a community development approach to build the leadership capacity of low-income women. The Aparecio Foundation pr ...

    Chicago, IL

    17 hours ago

  • Work in company

    Data Science

    Only for registered members

    · Who Are We? · Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, te ...

    Chicago, IL

    17 hours ago

  • Work in company

    Data Science

    Only for registered members

    Who Are We? · Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by integrating a connected platform enabled by smart data science t ...

    Chicago, IL

    2 weeks ago

  • Work in company

    VOLUNTEER / Intern MENTOR PROGRAM DEVELOPMENT CONSULTANT

    Only for registered members

    · Company Description · The Aparecio Foundation is a nonprofit organization that was designed as an economic development strategy to lift women out of poverty and as a community development approach to build the leadership capacity of low-income women. The Aparecio Foundation pr ...

    Chicago, IL

    17 hours ago

  • Work in company

    Private Credit Underwriting Associate

    Connect Search, LLC

    The Role · A front office underwriting seat where you'll be embedded within a deal team, working alongside junior and senior underwriters on new transactions and portfolio accounts. · Considering making an application for this job Check all the details in this job description, a ...

    Chicago

    1 day ago

  • Work in company

    Summer 2026 Investment Associate - No Solicitors

    Chicago Pacific Founders

    FIRM OVERVIEW · Based in Chicago and San Francisco, Chicago Pacific Founders (CPF) is a leading strategic private equity firm focused exclusively on building and scaling companies across the healthcare services sector. CPF invests in organizations driving innovation in value-base ...

    Chicago

    1 day ago

  • Work in company

    Senior Data Scientist

    Only for registered members

    · Priority will be given to applications received by Monday, February 23, but applications will continue to be reviewed on a rolling basis until the position is filled. · ABOUT THE RICHARD L. DUCHOSSOIS FOUNDATION · The Richard L. Duchossois Foundation (RLD) was founded in 2022 ...

    Chicago, IL $140,000 - $220,000 (USD) per year

    17 hours ago

  • Work in company

    Senior Data Scientist

    Only for registered members

    RLD Foundation seeks a mission-driven Senior Data Scientist & AI Engineer to join our Data Strategy & Insights team. In this role, you will play a central part in advancing the foundation's data strategy in a highly collaborative environment. · Build and own RLD Foundation's core ...

    Chicago, IL

    1 month ago

  • Work in company Remote job

    Data Scientist

    Only for registered members

    Huron is a global consultancy that collaborates with clients to drive strategic growth, ignite innovation and navigate constant change. Through a combination of strategy, expertise and creativity, we help clients accelerate operational, digital and cultural transformation, enabli ...

    Chicago, IL $85,000 - $150,000 (USD) per year

    2 weeks ago

  • Work in company

    Quantitative Option Pricing Intern

    Only for registered members

    · If you are looking to join a small, dynamic, growing firm in the financial technology sector, you have come to the right place. BlackEdge has built a strong foundation of success as an industry leading market maker in the treasury options space. Now we need talented people lik ...

    Chicago

    17 hours ago

  • Work in company

    AI Engineer – Entry Level Sales Program 2026

    Only for registered members

    In a world where technology moves at speed, it's essential that we stay ahead of the curve to provide tailored solutions that meet our clients' needs. · ...

    Chicago, IL

    1 month ago

  • Work in company

    AWS Partnership Lead – Senior Sales

    Only for registered members

    About the team: · At the Capco Technology Delivery Center, we are dedicated to the financial services industries. Our professionals combine innovative thinking with unrivalled industry and domain expertise to offer our clients consulting expertise, complex technology and package ...

    Chicago, IL

    1 week ago

  • Work in company

    Microsoft Partnerships Program Manager – Global GTM Enablement

    Only for registered members

    · About the team:   · At the Capco Technology Delivery Center, we are dedicated to the financial services industries. Our professionals combine innovative thinking with unrivalled industry and domain expertise to offer our clients consulting expertise, complex technology and pac ...

    US - Chicago

    17 hours ago

  • Work in company

    AWS Partnership Lead – Senior Sales

    Only for registered members

    · About the team:   · At the Capco Technology Delivery Center, we are dedicated to the financial services industries. Our professionals combine innovative thinking with unrivalled industry and domain expertise to offer our clients consulting expertise, complex technology and pac ...

    US - Chicago

    18 hours ago

  • Work in company

    Senior Data Scientist

    Only for registered members

    We're hiring a mid-level Data Scientist to play a foundational role in shaping how AI/ML is applied across our Personal Umbrella Policy (PUP) and E&S Property lines of business. · 3–5 years of hands-on experience in applied data science or machine learning roles. · Proficiency in ...

    Chicago, IL

    1 month ago

  • Work in company

    AI Architect

    Only for registered members

    We at Coforge are hiring an AI Architect with following skill-set: · Lead the design and implementation of end-to-end AI systems.Lead the implementation of best practices for deploying and serving various types of AI models. · ...

    Chicago, IL

    1 month ago

  • Work in company Remote job

    Lead Data Engineer

    Only for registered members

    This is a chance to own and shape data engineering within a large enterprise environment: · • Lead improvements to data architecture across Snowflake, dbt and Tableau · ...

    Chicago, IL

    1 month ago

  • Work in company

    Senior Director of Corporate and Foundation Relations

    Only for registered members

    Chicago, IL · Hybrid - 3 days onsite · Position Overview · Join a purpose-driven team working to end hunger and tackle its root causes through community partnerships, advocacy, and direct food distribution. Every role contributes to a powerful mission that helps provide millions ...

    Chicago, IL $155,000 - $260,000 (USD) per year

    5 days ago

  • Work in company

    Volunteer SEO Specialist

    Only for registered members

    · Company Description · The Aparecio Foundation is a nonprofit organization that was designed as an economic development strategy to lift women out of poverty and as a community development approach to build the leadership capacity of low-income women. The Aparecio Foundation pr ...

    P.O. Box a, Chicago, IL

    17 hours ago

Jobs
>
Chicago