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- Lead scientific efforts to characterize metabolic fate and pharmacokinetic properties of drug candidates (small molecules, biologics, and novel modalities) to inform and direct lead optimization of drug candidates; proactively identify issues and enable investigative efforts that further enhance optimization of drug candidates
- Work collaboratively with the San Diego-based DMPK team and internal partners to design, plan, execute and interpret DMPK studies. The incumbent is expected to advise on strategies to resolve DMPK issues that arise on programs.
- Work collaboratively with DMPK scientists across BMS discovery sites to enable strategic integration of DMPK research across the discovery portfolio
- Ensure that the DMPK team is current with emerging concepts and technologies so that these tools can be applied as appropriate for issues resolution.
- Work closely and collaboratively with colleagues in other functions of PCO, including discovery toxicology, pharmaceutics and analytical sciences to ensure a coordinated approach to discovery efforts.
- Maintain a strong external presence in the DMPK community through publications and conference presentations.
- Effectively lead, manage and develop DMPK scientists
- Ph.D. degree in any area of drug disposition, with emphasis on metabolism, pharmacokinetics or biochemical toxicology, with experience in drug discovery and development. Knowledge of computational approaches, including machine learning tools, to advance predictive tools for ADME-related aspects of drug discovery is desired.
- At least 8 years of experience in conducting and leading research efforts in drug metabolism and pharmacokinetics
- At least 6+ years of leadership experience
- Proven track record of problem-solving skills and ability to integrate across disciplines to address issues and identify mitigation strategies.
- Highly effective written and oral communication skills including contributions to the published literature.
- Strong interpersonal skills with evidence for effective management of a dynamic team and commitment to professional development of all personnel.
Director, Drug Metabolism and Pharmacokinetics - San Diego, CA, United States - Bristol Myers Squibb
Description
Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit eeo -accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. #J-18808-Ljbffr