- Proactive and hands-on role in establishing AMDI's cell culture and protein production.
- Design and carry out lab work to express, scale up, purify, and characterize novel proteins, and protein conjugates based on assay requirements.
- Design and make protein expression constructs.
- Use a broad range of protein analytical techniques including, but not limited to, HPLC, SPR, and SDS-PAGE to characterize purity, stability, and binding characteristics of protein batches.
- Be a subject matter expert in protein production and analytics and provide input to all development projects.
- Develop, implement, and participate effectively in developing processes for incoming QC of biologicals.
- Be able and comfortable to look for details in literatures, patents, posters, and presentations from other sources to solve technical problems.
- Document ongoing experiments and test protocols, summarize data, and present in group meetings.
- Document material specifications, manufacturing procedures, and equipment operating procedures.
- Recording of experimental data in an electronic LabArchives lab notebook following good laboratory notebook practices to ensure proper traceability and sharing of results with a supervisor or other team members.
- Effectively manage projects and resources. Interface with quality and manufacturing staff to ensure reliable integration, scale-up, and transition to production.
- Carry out preventative maintenance of laboratory equipment, as needed.
- Work on other research projects and help with other assignments or projects as the need arises with other team members.
- Minimum of a bachelor's degree in Biochemistry, Molecular Biology or Structural Biology, or a closely related field and/or equivalent experience in bioanalytical characterization is required. Master's degree preferred.
- Minimum of 2 years of experience in protein production (Baterial or mammalian cells).
- Minimum of 2 years of experience in protein purification (FPLC), protein characterization (HPLC, gel/capillary electrophoresis, binding studies, or stability assessments).
- Minimum of 2 years of experience in molecular biology techniques (PCR, qPCR)
- Motivated team player with attention to detail, a strong sense of ownership and responsibility, and the ability to prioritize work in a fast-paced environment are critical.
- Excellent organizational skills and ability to plan ahead and be proactive.
- Strong written and verbal communication skills.
- Excellent computer skills in Excel, Word, and Outlook. Prior experience with analytical software, electronic lab notebooks, etc.
- Ability to collaborate with other team members to work on projects
- Previous experience in research environment at biotech;
- Previous experience with working in a BSL2 laboratory environment;
- Previous experience in nucleic acids and protein chemistry (labeling and bioconjugation);
- Previous experience in protein engineering (Mutagenesis and fusions);
- Previous experience in in vitro CRPISR/Cas assays.
- Onsite work at Menlo Park facility, possibly travel to Santa Ana location should the need arise.
- Requires the use of personal protective equipment to prevent exposure to biohazardous waste and chemicals
- BSL2 and sterile lab environment
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Associate Scientist - Menlo Park, United States - Autonomous Medical Devices Incorporated
3 weeks ago
Description
Job Description
Job DescriptionAutonomous Medical Devices Incorporated (AMDI), with its principal place of business in California, employs a world class team of engineers, scientists, clinicians, and manufacturing experts dedicated to the development and manufacture of point-of-care diagnostic devices using breakthrough microfluidics, protein engineering, and data/cloud connectivity. AMDI will launch its first products from its ISO:13485 certified 110,000 square foot facility in Santa Ana, CA.
Summary of Position
We are seeking a highly motivated Associate Scientist to join our team. The individual will take a hands-on role in the development, purification, and characterization of proteins, antibodies, and related biological reagents used in proprietary POC microfluidic assays. They will also assist in developing QC processes for these biologicals, drafting SOPs, and process improvement activities. The successful candidate will have demonstrated an in-depth understanding of mammalian cell culture, protein purification/characterization, and molecular biology techniques and be able to thrive in a fast-paced environment. The Associate Scientist will be based out of our location in Menlo Park, CA.
Essential Duties and Responsibilities
Qualifications Required for Position
Desired skills and traits
Work Environment
Autonomous Medical Device Incorporated offers a comprehensive compensation and benefits package to eligible employees including:
Company provided lunch to all employees when working at one of AMDI's on-site locations.
401(k) match
Health insurance, 100% paid for by employer including: Medical, Dental, Vision & Life Insurance
Competitive vacation, sick days & paid holidays
Tuition reimbursement
Casual dress code
Employee discounts on activities such as theme parks, movie theaters, hotels, rental cars, etc.
Monthly company-wide socials
Autonomous Medical Devices Incorporated (AMDI) will not accept unsolicited resumes from any source other than directly from a candidate. An Agency must obtain advance written approval from AMDI's internal Human Resources team to submit resumes only in conjunction with approved valid fully executed contracts.
Our commitment to an inclusive workplace:
We are an equal opportunity employer and encourage people from all backgrounds to apply. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status, or any other protected characteristic under federal, state, or local law.
Company DescriptionAutonomous Medical Devices Incorporated (AMDI), with its principal place of business in California, employs a world class team of engineers, scientists, clinicians, and manufacturing experts dedicated to the development and manufacture of point-of-care diagnostic devices using breakthrough microfluidics, protein engineering, and data/cloud connectivity. AMDI will launch its first products from its ISO:13485 certified 110,000 square foot facility in Santa Ana, CA.