- Engage with the clinical and biomarker teams to organize and extract evidence of activity and other biological insights from emerging clinical data
- Analyze complex multi-omics data sets across various modalities and connect insights and observations to clinical endpoints, highlighting possible indication expansion for key targets
- Contribute to the translational computational strategy for a number of exciting early-and late-stage targets in the Remix portfolio, as well as partnered targets across diverse disease areas
- Mine public and private multi-omic datasets including real-world data relating to Remix target areas for insights into patient stratification and biomarker strategies for early and late stage programs across Remix target areas, with a current focus on oncology and neurodegeneration
- Work with internal groups at Remix as well as external partners to solve problems using cutting-edge data analysis and visualization
- Participate and thrive in a culture of effective collaboration between experimental and computational scientists
- PhD in Computational Biology, Bioinformatics, or Computer Science, with 7+ years of total experience working in disease target areas relevant to Remix, especially oncology and/or neurodegeneration
- Outstanding bioinformatics programming skills in at least one language relevant to data analysis such as Python or R
- Ability to effectively communicate methodologies and results with colleagues, including bench scientists, research management, and project team leaders
- Knowledge of RNA biology a plus, especially RNA splicing
- Strong leadership skills
- Strong problem-solving and troubleshooting skills
- Ability to work in a dynamic and fast-paced environment independently and efficiently
- Authorized to legally work in the US
-
Associate Director, Bioinformatics
2 weeks ago
Remix Therapeutics Watertown, United StatesRemix launched with a vision to transform patient's lives through modulation of RNA processing. Our breakthrough science provides a path to identify small molecules that impact the expression of disease driving mRNAs and proteins. We take on the challenge of addressing drug targe ...
-
Director, Bioinformatics Core
1 week ago
Knewin Boston, MA, United StatesWhen you join the growing BILH team, you're not just taking a job, you're making a difference in people's lives. · Job Type: · Regular Scheduled Hours: · 40 Work Shift: · Day (United States of America) About us: The BIDMC Bioinformatics Core (BBC) is part of the Precisio ...
-
Senior Director, Translational Biomarkers
6 days ago
Dyne Therapeutics, Inc. Waltham, United StatesCompany Overview: · Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE platform, Dyne is developing modern oligonucleotide thera ...
-
Senior Director, Translational Biomarkers
6 days ago
BioSpace Waltham, United StatesJob Details · Company Overview: · Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCETM platform, Dyne is developing modern olig ...
-
Senior Software Engineer, GA4GH
4 days ago
Broad Institute Cambridge, United StatesGeneral information · Location · Cambridge, MA · Ref # · 39189 · Job Family · Research · Date published · 30-Apr-2024 · Time Type · Full time · Description & Requirements · Job Description · The Global Alliance for Genomics and Health (GA4GH) is an international open ...
-
Associate Director, Oncology Genomics
1 week ago
GlaxoSmithKline Cambridge, United StatesSite Name: · USA - Pennsylvania - Upper Providence, Heidelberg, UK - Hertfordshire - Stevenage, USA - Massachusetts - Cambridge · Posted Date: · Apr · We are seeking a highly skilled and experienced individual to join our team as an · Associate Director of Oncology Genomics ...
-
Senior Director, Translational Biomarkers
3 weeks ago
Dyne Therapeutics Waltham, United States Full timeCompany Overview: · Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCETM platform, Dyne is developing modern oligonucleotide the ...
-
Associate Director, Commercial Diagnostics
2 weeks ago
Sarepta Therapeutics Cambridge, United StatesThe Associate Director, Commercial Diagnostics & Bioinformatics reports into the Executive Director, Commercial Diagnostics and plays a key role in driving the strategic vision and objectives to make Sarepta a recognized leader in precision genetic medicine for rare diseases. The ...
-
Associate Director, Commercial Diagnostics
1 week ago
Sarepta Therapeutics Cambridge, United StatesThe Associate Director, Commercial Diagnostics & Bioinformatics reports into the Executive Director, Commercial Diagnostics and plays a key role in driving the strategic vision and objectives to make Sarepta a recognized leader in precision genetic medicine for rare diseases. The ...
-
Postdoctoral Research Fellows
1 week ago
Forsyth Cambridge, United StatesApply · Description · The Forsyth Institute is a world leader in the field of Dental and Craniofacial Research. Located in the Cambridge area, an epicenter of biomedical research, the campus is with one of the highest densities of colleges and innovations and offers collaboration ...
-
Associate Director, Commercial Diagnostics
3 hours ago
Sarepta Therapeutics Cambridge, United StatesThe Associate Director, Commercial Diagnostics & Bioinformatics reports into the Executive Director, Commercial Diagnostics and plays a key role in driving the strategic vision and objectives to make Sarepta a recognized leader in precision genetic medicine for rare diseases. The ...
-
Director, Computational Design
3 days ago
Moderna Therapeutics CAMBRIDGE, MA, United StatesThe Role:Moderna Infectious Disease is seeking an exceptionally talented, highly creative, and motivated senior scientific leader with a broad skill base in computational protein design, structural informatics, in vitro evolution, and vaccine design, to lead computational antigen ...
-
Director of Information Technology
1 week ago
Whitehead Institute for Biomedical Research Cambridge, United StatesClassification: · Exempt · Job Family: · Senior Management · Reports to: · Vice President and COO · Job Description Summary: · Reporting to the Vice President and Chief Operating Officer, the Director oversees 20 IT staff that sustain and support the research computing, ...
-
Associate Director, Computational Methods
1 week ago
Broad Institute Cambridge, United StatesJob DescriptionMethods Development Lab:The combination of molecular and computational advances over the past decade has substantially augmented our ability to create transformative methods. While this accelerated pace of methods development offers great promise, the rapid expansi ...
-
Associate Director, Computational Methods
1 week ago
Broad Institute Cambridge, United StatesJob DescriptionMethods Development Lab:The combination of molecular and computational advances over the past decade has substantially augmented our ability to create transformative methods. While this accelerated pace of methods development offers great promise, the rapid expansi ...
-
Director of Information Technology
1 week ago
MIT Cambridge, United StatesDirector of Information Technology page is loaded · Director of Information Technology · Apply · locations · Cambridge, MA · time type · Full time · posted on · Posted 6 Days Ago · job requisition id · JR100153 · Classification: · Exempt · Job Family: · Senior Managem ...
-
Associate Director, Computational Methods
1 week ago
Broad Institute Cambridge, United StatesJob DescriptionMethods Development Lab:The combination of molecular and computational advances over the past decade has substantially augmented our ability to create transformative methods. · You can get further details about the nature of this opening, and what is expected from ...
-
VP, Laboratory Medical
6 days ago
Exact Sciences Cambridge, United States OTHERHelp us change lives · At Exact Sciences, we're helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an ...
-
Moderna, Inc. Cambridge, MA, United StatesThe Role: · We are seeking a talented and experienced Director to lead our in vivo pharmacology research team. The successful candidate will play an integral role across our oncology research groups, overseeing the development of relevant in vivo animal and cell models, and the ...
-
BioSpace Cambridge, MA, United StatesJob Details · The Role: · We are seeking a talented and experienced Director to lead our in vivo pharmacology research team. The successful candidate will play an integral role across our oncology research groups, overseeing the development of relevant in vivo animal and cell mo ...
Associate Director, Bioinformatics - Watertown, United States - Remix Therapeutics
20 hours ago
Description
Remix launched with a vision to transform patient's lives through modulation of RNA processing. Our breakthrough science provides a path to identify small molecules that impact the expression of disease driving mRNAs and proteins. We take on the challenge of addressing drug targets in diseases of high unmet medical need to bring new therapeutic options to patients. Remix has a commitment to demonstrate the highest levels of scientific integrity with urgency because those patients are counting on us to deliver. With an in-house technology platform built from scratch, we have rapidly generated multiple drug discovery programs that are advancing towards the clinic.
We seek a highly motivated, experienced translational bioinformatic leader to join our team located in Watertown, MA. As a translational bioinformatician reporting to the Head of bioinformatics and data science, this person will direct in collaboration with a cross-functional team of scientists and clinical experts the translational strategy and multi-omics analysis of complex data sets for the different projects leading to the development of novel RNA processing medicines. The ideal candidate will have a strong background in bioinformatics as well as translational expertise in one or more target areas relevant to Remix, especially oncology and/or neurodegeneration, and will be driven to succeed within a hypothesis-driven, team-oriented, and interdisciplinary biotech environment. The individual will be expected to contribute to all stages of drug development, supporting the translational efforts from the preclinical stage to marketing.
Principle duties and responsibilities:
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Remix Therapeutics is not responsible for any fees related to resumes that are unsolicited.