-
Associate Director, Hit Discovery
1 day ago
Life Edit Therapeutics Durham, United States Full timeThe Role: · Life Edit is seeking an experienced scientific leader with direct industry experience in therapeutic hit discovery. The selected candidate will report to the Director, Gene Editing and lead a group of scientists to perform target exploration within the Gene Editing te ...
-
Adams & Martin Group Raleigh, United StatesAdams & Martin Group is working with law firms through LA and Orange County in upcoming needs for temporary attorney coverage. Firms have increased work/caseloads that require extra help on particular matters. Hours may begin part-time with the opportunity to grow to full-time or ...
-
Discovery Chemistry Principal Scientist
1 week ago
SpringWorks Therapeutics Raleigh, United StatesAbout SpringWorks TherapeuticsSpringWorks is a clinical-stage biopharmaceutical company applying a precision medicine approach to acquiring, developing and commercializing life-changing medicines for patients living with severe rare diseases and cancer. SpringWorks has a differen ...
-
Manager/Sr. Manager Facilities
4 days ago
Charles River Durham, United StatesFor 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
-
Synthetic Chemist
4 days ago
Actalent Durham, United States: · The Synthetic Chemist will serve as a member of chemistry project teams, contributing through synthetic and medicinal chemistry to advance projects from hit identification through nomination of development candidates. This role will exist within a culture of scientific excell ...
-
Director, In Vivo Operations
1 day ago
Charles River Laboratories Durham, United StatesDirector, In Vivo Operations · Req ID #: · Location: · Durham, NC, US, 27709 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant ...
-
Manager/Sr. Manager Facilities
2 days ago
Charles River Laboratories Durham, United StatesManager/Sr. Manager Facilities · Req ID #: · Location: · Durham, NC, US, 27709 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significan ...
-
Manager/Sr. Manager Facilities
4 days ago
Charles River Laboratories Durham, United StatesManager/Sr. Manager Facilities · Req ID #: · Location · Durham, NC, US, 27709 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant ...
-
Biomason, Inc. Durham, United StatesJob Description · Job DescriptionCompany Overview: Are you a results-driven problem-solver, eager to positively change the world? Do you believe that climate change is the biggest issue facing us today? Then the Biomason team needs you Biomason is leading the global transition to ...
-
Human Resources Business Partner
2 weeks ago
Charles River Laboratories, Research Models and Services, Germany GmbH Durham, United StatesPress Tab to Move to Skip to Content Link · Select how often (in days) to receive an alert: · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a s ...
-
Human Resources Business Partner
1 week ago
Charles River Laboratories Durham, United StatesHuman Resources Business Partner · Req ID #: · Location: · Durham, NC, US, 27709 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a signific ...
-
Director, In Vivo Operations
1 week ago
Charles River Laboratories Durham, United StatesFor 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
-
Postdoctoral Medicinal Chemist
1 week ago
RTI International Durham, United StatesOverview: · The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization. We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry ...
-
Human Resources Business Partner
6 days ago
Charles River Laboratories, Inc. Durham, United StatesFor 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
-
Manager/Sr. Manager Facilities
6 days ago
Charles River Laboratories, Inc. Durham, United StatesFor 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your backgr ...
Associate Director, Hit Discovery - Raleigh, United States - ElevateBio
Description
Life Edit is seeking an experienced scientific leader with direct industry experience in therapeutic hit discovery.The selected candidate will report to the Director, Gene Editing and lead a group of scientists to perform target exploration within the Gene Editing team.
Here's What You'll Do:
Lead a diverse scientific team to devise gene editing strategies for targets of interest, execute editing screening campaigns, and perform hit-to-lead activities including
in vitro
proof-of-concept and mechanism of action studies
Work closely with Corporate Development to help identify novel therapeutic targets, taking into account multiple factors including technical feasibility, commercial opportunity, and business strategy
Collaborate with the Computational Biology, Technology Development, and Preclinical teams to deploy Life Edit's array of genome editing systems and move lead editing compositions into animal models
Ensure hit discovery and optimization activities meet key milestones in a timely manner
Critically summarize and present data internally to interdisciplinary teams and leadership, as well as externally
Write reports summarizing hit discovery and optimization activities suitable for inclusion in regulatory documents
Requirements:
Ph.
D. in biology, biochemistry, molecular biology, or a related field with 10+ years of relevant experience
Direct experience with hit discovery and hit-to-lead activities in the pharmaceutical or biotechnology sectors, industry experience preferred
Experience leading a scientific team, preferably in an industry setting
Demonstrated ability to collaborate in a cross functional, team-oriented environment
Exceptional oral and written communication skills
Relevant technical skills for data analysis, electronic lab notebook documentation, and presentations
Direct experience in the gene editing field is strongly preferred
A broad background in a variety of areas in biology and human therapeutics is advantageous
We're committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start.
Medical, vision, and dental insurance covered at 90%
Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
Annual fitness reimbursement
Employer paid for access to wellness apps and programs like Task Human
Competitive compensation
401(k) retirement plans with a 4% employer match and no vesting period
Employer-paid life insurance and short- and long-term disability insurance
Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA)
Access to a 1-on-1 financial advisor
Monthly cell phone stipend
Time Off & Flexibility
Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
18 paid company holidays, plus an end-of-year holiday shut down
12 weeks of parental leave
Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum
Development Journey
Insights Discovery training for every employee to make the most of workplace relationships
Access to LinkedIn Leaning, a self-guided online education platform
Why join Life Edit and the ElevateBio ecosystem?
Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine.
Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics.
Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.Life Edit is an integral part of ElevateBio's ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics.
Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA.
Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies.
We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.
Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.
Our Vision:
We seek to be the world's most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.
ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.#J-18808-Ljbffr
