Associate Director, Medicinal Chemistry, TTD, Early Oncology - Waltham, United States - AstraZeneca

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    Description
  • Associate Director, Medicinal Chemistry, TTD, Early Oncology
  • This role is part of our strategy to deliver next generation of therapeutics including, but not limited to, small molecule, peptide and antibody drug conjugates to treat cancer.
  • Close collaboration with computational chemistry, in vivo pharmacology, structure biology, and related functions will be required.
  • Design and develop modular strategies compatible for rapid access to small molecule targets (strong organic synthesis and medicinal chemistry background is required)
  • Doctoral degree (Ph. D.) focused on synthetic organic chemistry or medicinal chemistry with 5+ years of experience in biotech and/or pharmaceutical industry setting.
  • A strong track record of scientific innovation as medicinal chemistry project lead and portfolio milestone success
  • Deep knowledge of ADME, physicochemical, biochemical, and pharmacological principles as applied to small molecules
  • Subject matter expert in organic synthesis and methodology, with general knowledge of the mechanisms of chemical reactivity and awareness of latest scientific literature to guide the chemistry team