- The position will independently provide bioinformatics and genomics project support to the Molecular Pathology Group within the Comparative and Molecular Pathogenesis Branch, Division of Translational Toxicology.
- Coordinate the progress on multiple bioinformatics projects in various stages of completion while taking principal responsibility on projects as needed
- Collaborate with and support scientists to design experiments, analyze and interpret high throughput biological data
- Write relevant sections of manuscripts, prepare publication quality figures
- Establish reproducible data analysis pipelines and standard operating procedures (SOPs)
- Master's
- Amazon Web Services (AWS) Certification
- Whole Genome Sequencing
- Next gen sequencing data analysis: Bulk RNA-Sequencing
- Microarray data analysis
- Work with large data sets
- Clinical and/or translational research
- SQL
- R
- PERL
- Python
- Linux
- Genetics
- Molecular Biology
- Computer Programming and Data Processing
- Statistics and Decision Science
- Provides programming and troubleshooting support to the Federal Government in the dissemination of research data.
- Generate and optimize programs and scripts for the analysis of data; create programs and algorithms and develop computational infrastructure resources for organizing and parsing data from large and complex data.
- Serve as bioinformatics expert and coordinate with teams of biologists to conduct experimental queries and/or perform portions of studies using complex procedures and techniques common to modern bioinformatics.
- Coordinate building bioinformatics infrastructure to ensure easy and meaningful scientific analysis and interpretation of data.
- Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects.
- Install, troubleshoot and run open-source and commercial scientific software on platforms
- Perform computational analysis of, and interpret results.
- Provide reports based on analysis of scientific data.
- Perform sequencing and alignment of raw data, and interpret new data using larger public access datasets.
- Provide interpretive analyses of data derived from different experimental platforms to generate biological meaning.
- Write custom programs and algorithms to support data analyses and discovery.
- Collaborate with scientists to design, analyze, manage and interpret all types of data.
- Design and execute computational experiments.
- Work with staff on planning of experiments, and data analysis for internal and collaborative projects; use bioinformatics expertise to advise and help bench scientists on experimental design and trouble-shooting.
- Work with staff to develop specifications for new analysis; design, test and implement solutions.
- Make recommendations to investigators about the correct computational tools for testing scientific hypotheses and reaching valid conclusions.
- Maintain proper and detailed documentation of the analysis performed and report results at lab meetings.
- Attend scientific and programming meetings; take and compile comprehensive notes; organize and edit content of meeting reports.
- Prepare scientific reports and progress reports; assemble data to prepare tables, graphs and slides; conduct scientific and program related information searches and report results.
- Organize daily laboratory notebook on experiments; prepare weekly updates on on-going experiments and tasks; provide monthly progress notes on assigned projects; submit final progress reports and future directions on projects.
- Organize laboratory notebook or computer database to record results of calculations. Share results at lab meetings.
- Devise Client methods of statistical analysis for collected data.
- Utilize and adapt existing bioinformatics techniques to check for trends and patterns in the data.
- Write complex queries to multiple databases.
- Perform data processing and data analysis with existing computational and statistical methods.
- Assist in evaluating and interpreting results for validity and scientific meaning.
- Create Client programs and algorithms that facilitate discovery of knowledge in investigating large and complex data.
- Develop and optimize programs and scripts that facilitate organization, integration and data-mining of large data sets; integrate these models into a framework of best practices.
- Participate in the design of new protocols involving computational methods.
- Work with staff on the development and maintenance of bioinformatics tools, scripts and pipe-lines for data.
- Participate in research design with investigators for determining best practices pertaining to the bioinformatics analysis in new and ongoing projects.
- Research and review literature to retrieve targeted clinical or scientific information, including Client statistical methods, from publicly available resources.
- Collaborate with staff to review current and historical procedures for the acquisition, quality control and management of data.
- Analyze and evaluate data cleaning and harmonization needs in the using a variety of descriptive statistics and analytic methods.
- Identify new tools and resources for reaching biologically meaningful conclusions.
- Collaborate with experimentalists and computational biologists to develop new computational tools to answer research questions of interest.
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Bioinformatics Analyst - Durham, United States - 22nd Century Healthcare
Description
Job Title: Bioinformatics Scientist
Location: Research Triangle Park, NC 27709
Duration: 3 Years to Permanent
Shift: 40 Hours/Week (Mon to Fri)
Onsite: Yes ; Teleworking Eligible: Yes
Overall Position Summary and Objectives:
Statement of Work Details:
Min Education:
Certifications & Licenses Preferred:
Skills:
Software:
Field of Study:
Statement of Work Details:
Performs computations on research data analysis.
Works with staff on scientific programming and experimental design.
Records observations and report results at weekly laboratory meetings.
Provides statistical support / analysis on research data.
Provides research / service goals in the context of the laboratory's overall mission.
Evaluates new types of experimental approaches to protocols based on knowledge of scientific literature, available facilities and research needs.