Jobs
>
Franklin

    Research Assistant, Senior, Basic Sciences - Franklin, United States - Vanderbilt University

    Vanderbilt University background
    Description

    This position is part of the Warren Center for Neuroscience Drug Discovery (WCNDD) at Vanderbilt University where traditional academic pursuits in basic science are extended to advance our understanding of human disease and drug targets to directly impact patient care.

    The position calls for a motivated biological scientist to join the Molecular Pharmacology group within the WCNDD.

    The Pharmacology team is responsible for conducting high-throughput screening assay of small molecule modulators of GPCRs, ion channels, and kinases.

    This includes development of target protein cell lines and pharmacological assay to lead and support all molecular pharmacology activities.

    This position is a key contributor to support the Center's goal of developing therapeutics, specifically for central nervous system disorders.

    Successful candidates will interface with members among all areas of the WCNDD, including those in molecular pharmacology, medicinal chemistry, drug metabolism and pharmacokinetics, and in vivo rodent pharmacology.


    Duties and Responsibilities:
    We are all different, yet we all use our unique contributions to serve patients. The Molecular Pharmacology Research Assistant Senior we seek is a person with these qualifications.


    • Perform in vitro pharmacological experiments independently or under moderate supervision.
    • Conduct high-throughput cell-based screening assays using fluorescent-based plate kinetic readers in support of characterizing GPCR- and ion-channel targeted small molecule drugs.
    • Conduct high-throughput TR-FRET screening assays in support of developing selective kinase inhibitors.
    • Operate multi forms of liquid handling equipment, and automation units.
    • Maintain mammalian cell lines used in the screening assays.
    • Develop stable cell lines specific to new target proteins.
    • Perform molecular biology experiments involving preparation and analysis of DNA/RNA and Protein samples.
    • Train junior research associates in pharmacological assay, equipment operation/maintenance, and data analysis.
    • Contribute to the effective operation of the lab by ordering supplies, maintaining equipment, and ensuring compliance with VEHS biological and chemical safety requirements.
    • Write up pharmacological assay protocols applicable to assigned tasks.
    • Analyze data to determine the efficacy and potency of the compounds using data analysis software.
    • Maintains accurate databases and experimental notebooks of results.
    Qualifications


    • Bachelor's degree with 4 plus years of relevant working experience or Master's degree (MS) with 2 years of relevant work experience.
    • Degree in biology, biochemistry, or pharmacology is necessary.
    • A minimum 3 years' experience in mammalian cell culture is necessary.
    • Hands-on experience of plasmid preparation, transfection, and Western Blotting.
    • Excellent oral and written communication skills, excellent data analysis capabilities, and proficiency with curve fitting and graphing programs are essential.
    • Good documentation practices with excellent organization and attention to detail
    • Self-motivated team player with the ability to thrive in a fast paced, dynamic, multi-disciplinary, matrixed environment.
    Commitment to Equity, Diversity, and Inclusion


    At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff.

    Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive.

    As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone.

    The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.

    Vanderbilt University is an equal-opportunity employer.

    All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran, or any other characteristic protected by law.


    Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.



  • Vanderbilt University Franklin, United States

    Job Description · This position is part of the Warren Center for Neuroscience Drug Discovery (WCNDD) at Vanderbilt University where traditional academic pursuits in basic science are extended to advance our understanding of human disease and drug targets to directly impact patie ...


  • Vanderbilt University Franklin, United States

    Job Description · This position is part of the Warren Center for Neuroscience Drug Discovery (WCNDD) at Vanderbilt University where traditional academic pursuits in basic science are extended to advance our understanding of human disease and drug targets to directly impact patie ...


  • Vanderbilt University Franklin, United States

    Job Description · This position is part of the Warren Center for Neuroscience Drug Discovery (WCNDD) at Vanderbilt University where traditional academic pursuits in basic science are extended to advance our understanding of human disease and drug targets to directly impact patie ...


  • Middle Tennessee State University Murfreesboro, United States

    Job Summary/Basic Function · The College of Basic and Applied Sciences at Middle Tennessee State University invites applications for openings in Academic Advisor position in the Sciences. This position will have a particular emphasis on working with students to increase retentio ...


  • Middle Tennessee State University Murfreesboro, United States

    Job Title · Advisor - College of Basic & Applied Sciences · Department · Basic and Applied Sciences Advising · Salary · $42,114 - $51,870; commensurate with experience · Job Summary/Basic Function · The College of Basic and Applied Sciences at Middle Tennessee State University in ...

  • UL Solutions

    Software Engineer

    3 weeks ago


    UL Solutions Franklin, United States

    Job Description · This role is REMOTE anywhere in the United States. · UL is seeking a Software Developer to join an experienced Scrum Team consisting of a Product Owner, Scrum Master, Quality Assurance Analysts, Software Engineers, Front-end Developers, and Architects. The can ...


  • EssilorLuxottica Franklin, United States

    Requisition ID: 846453 · Position:Part-Time · Oakley, Inc. is a sport and lifestyle brand, driven to ignite the imagination through the fusion of art and science. Building on its legacy of innovative, market-leading optical technology, the company manufactures and distributes h ...


  • First Bank Online Franklin, United States

    This position in NOT remote eligible and is in the office 5 days a week. The position can be located in either our Franklin, TN office or our Downtown Birmingham office. · Summary · This role will support the Encompass mortgage originating system effectiveness and operating eff ...


  • The Exercise Coach - Murfreesboro/Franklin Franklin, United States

    Job Description · Job DescriptionBenefits:Flexible schedule · Paid time off · Training & development · "If you have enthusiasm, a positive attitude and good communication, I have a fun and fulfilling Personal Training Position just for YOU" · We understand that everyone knows the ...


  • Vanderbilt University Medical Center Franklin, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...


  • Educational Media Foundation - K-LOVE & Air1 Franklin, United States

    Overview · As a Data & Business Systems Analyst III, you're the powerhouse behind our Data Services team, seamlessly blending the roles of business systems analyst, business data analyst, and data evangelist. Your mission? To drive user story development, craft compelling data v ...


  • Community Health System Franklin, United States

    Job Description · Community Health Systems is one of the nation's leading healthcare providers. Developing and operating healthcare delivery systems in 41 distinct markets across 15 states, CHS is committed to helping people get well and live healthier. CHS operates 74 acute-care ...


  • Money Fit by DRS Franklin, United States

    OMNIA Partners has become the largest and most experienced purchasing organization for public and private sector markets by delivering unparalleled scale and solutions. Through further organic growth and strategic acquisitions, OMNIA Partners will continue to drive economies of s ...


  • Vanderbilt University Medical Center Franklin, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...

  • Vanderbilt University Medical Center

    Rad Tech PRN

    4 weeks ago


    Vanderbilt University Medical Center Franklin, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...


  • Vanderbilt University Medical Center Franklin, TN, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...


  • Vanderbilt University Medical Center Franklin, TN, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...


  • Vanderbilt University Medical Center Franklin, TN, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...


  • Vanderbilt Health Franklin, United States

    Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is a p ...

  • Vanderbilt University Medical Center

    Lic Practical Nurse 2

    2 weeks ago


    Vanderbilt University Medical Center Franklin, TN, United States

    **Discover Vanderbilt University Medical Center:** Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery, and patient care, VUMC is a community of diverse individuals who come to work each day with the simple aim of changing the world. It is ...