Jobs

    Senior Scientist - California, United States - BioPhase

    BioPhase
    BioPhase California, United States

    3 weeks ago

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    Description

    Principal Scientist / Senior Scientist

    Position Summary:

    We are actively seeking a highly skilled and experienced Analytical Senior Scientist or Scientist to join our dynamic team. The successful candidate will be responsible for designing and executing experiments to characterize, stabilize, and understand the degradation pathways of small molecule drug candidates, particularly for injectable products.

    Role and Responsibilities:

    - Independently plan, design, execute, and interpret experiments to solve complex problems in small molecule chemistry.

    Operate and maintain analytical equipment such as HPLC-UV and LC-MS.

    Develop protocols and write detailed reports to document experimental results.

    Create and optimize analytical methods for the characterization and evaluation of drug product prototypes.

    Investigate formulation properties including solubility, stability, and drug release profiles for various dosage forms like lyophilized products and sterile injectable suspensions.

    Maintain rigorous documentation to comply with scientific, regulatory, and intellectual property standards.

    - Show initiative and creativity in contributing to projects and achieving company goals.

    Location:

    San Diego, CA - This is a full-time, onsite position

    Key Qualifications & Competencies:

    Bachelor's degree in Chemistry or a related field; advanced degrees (MS or PhD) preferred.

    At least 4 years of experience in formulation and analytical development within a corporate setting, focusing on small molecules.

    Extensive experience with analytical techniques including HPLC-UV and LC-MS.

    Proven track record in early-stage development and characterization of sterile pharmaceutical formulations.

    Strong foundational knowledge in physical and organic chemistry, physical pharmacy, and materials science.

    Excellent collaboration skills and proven ability to design and analyze experiments.

    Effective communication and interpersonal skills, capable of working well within a team structure.

    Commitment to high ethical standards and integrity.

    Experience in preparing CMC documents for IND or other regulatory submissions is highly desirable.

    - Must understand the skills and techniques not just be able to perform them

    This role offers the opportunity to work in a fast-paced environment and make significant contributions to our innovative projects focused on improving patient outcomes through advanced drug development.


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