- Cover letter that describes your prior experience, career goals, and your motivation to apply for this position.
- CV with publication records. 3
- Name, relations and contact information for three references.
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Research Fellow
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Partners Healthcare System Charlestown, United StatesResearch Fellow Position in Molecular Biology with Immunology Experience · Job Summary: · The Manstein Laboratory at Massachusetts General Hospital is conducting research in dermatology, focusing on the development of novel, energy-based procedures for the treatment of various sk ...
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Point32Health Boston, United States**Who We Are** · Point32Health is a leading health and wellbeing organization, delivering an ever-better personalized health care experience to everyone in our communities. At Point32Health, we are building on the quality, nonprofit heritage of our founding organizations, Tufts H ...
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Mass General Physicians Organization(MGPO) Charlestown, United StatesPostdoctoral Fellow in Alzheimer's Disease Data Science · Department of Neurology, Massachusetts General Hospital and Harvard Medical School · We are seeking a highly motivated, innovative, and independent postdoctoral fellow to join the MassGeneral Institute for Neurodegenerativ ...
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Partners Healthcare System Charlestown, United StatesPost-doctoral Research Fellow position in Molecular Therapeutics · A Post-doctoral position is immediately available in the Investigational Cancer Therapeutics laboratory at Massachusetts General Hospital. The successful candidate will be affiliated with the Krantz Family Center ...
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Point32Health Boston, United States**Who We Are** · Point32Health is a leading health and wellbeing organization, delivering an ever-better personalized health care experience to everyone in our communities. At Point32Health, we are building on the quality, nonprofit heritage of our founding organizations, Tufts H ...
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Massachusetts General Hospital Somerville, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: · The McCance Center for Brain Health in the Department of Neurology at the Massachusetts General Hospital (MGH) is a Harvard-affiliated Center in Boston well-poised to the discovery of novel tools and interventions that promote brain health. ...
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Mass General Physicians Organization(MGPO) Boston, United StatesIn the research area of materials for drug and gene delivery, the Center for Systems Biology (CSB) at Massachusetts General Hospital (MGH) seeks applications for postdoctoral fellows interested in new methods for gene and drug delivery. Areas of interest include ultrasound, nanom ...
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Mass General Physicians Organization(MGPO) Boston, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: · Our laboratory applies computational, and machine learning methods to understand the impact of seizures and abnormal brain activity on outcomes in critically ill patients with brain injury. Our goal is to improve treatment strategies and the ...
Postdoctoral Research Fellow - Charlestown, United States - Partners Healthcare System
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Description
A postdoctoral position is available in the Dr.Victor Tkachev's laboratory at Massachusetts General Hospital - Harvard Medical School to study the immunobiology of Graft-versus-Host Disease (GVHD), which remains the major cause of morbidity and mortality of patients after allogeneic hematopoietic stem cell transplantation (HSCT).
Our group uses animal models, including unique HSCT model in non-human primates, traditional and systems immunology approaches to interrogate the mechanism driving pathogenic alloimmunity during GVHD.
Recently, we discovered that GVHD-induced tissue immunopathology in barrier organs is driven by tissue-infiltrating T cells that rapidly acquire pathogenic tissue-resident characteristics (Tkachev V et al, Sci. Transl. Med).This seminal discovery nominates potentially targetable pathways orchestrating tissue invasiveness and tissue-residency programs in T cells during GVHD and spark our interest to understanding the organ-specific roles of tissue-resident T cells in HSCT settings.
We are currently investigating whether specific targeting these cells provides the opportunity to separate GVHD, mainly affecting barrier organs, from beneficial graft-versus-leukemia (GVL) effect, primarily mediated in the lymphoid tissues.
The Dr.Victor Tkachev's laboratory is a recently established research unit within the MGH Center for Transplantation Sciences, which offers a great opportunity to get expertise in basic and translational immunology and to work in a highly productive, as well as highly collaborative and supportive multidisciplinary environment.
The indicated studies will be conducted as a part of existing collaboration involving Dr. Tkachev's laboratory, Cellular Therapeutics and Systems Immunology (CTSI) laboratory at Boston Children's Hospital, led by Dr. Leslie Kean, and other investigators within Harvard Medical School and beyond.
The Research Fellow will work to independently carry out a scientific project with minimal supervision from the PI of the laboratory.
This includes design and execution of highly specialized experiments, collection of and accurate recording of procedures and results, and summarization of the findings for publication.
Candidates must be highly motivated, well organized, technically proficient, critically minded, and able to work independently but collaboratively with others.
Candidates must possess a recent PhD, MD, or MD/PhD with a strong background in cellular or molecular immunology.Extra consideration will be given to those with relevant experience with T cell immunology, advanced flow cytometry, and systems biology.
To apply, please send the following materials to Dr.Victor Tkachev ):