- Enthusiasm and energy;
- Humble, servant leadership;
- Inquisitive and creative mind;
- Thrive on complex challenges;
- Ability to turn the conceptual into the tangible and actionable;
- Strong self-confidence with no ego;
- Looking for more than a job, but a purpose;
- Excellent interpersonal skills and the ability to persuasively sell ideas;
- Intellectual agility;
- Willingness to make difficult recommendations and decisions;
- Team first mentality;
- Independent thinking and data-driven decision-making;
- Strong interest in healthcare and entrepreneurship
- Enable the launch of companies developing novel cancer therapeutics
- Complete training to master the latest Schrodinger, Inc. computational chemistry software
- Evaluate and deploy effective cloud-based computational resources for free energy calculations
- Perform computer-based lead optimization for, and in consultation with, CPRIT ACT participants
- Participate in core facility staff meetings
- Participate in the augmentation of TMC ACT advisor network comprised of subject matter experts who will support the program and participating companies
- Participate in annual progress reports as dictated by the grant-awardee Cancer Prevention and Research Institute of Texas (CPRIT)
- Experience in computational chemistry, along with a strong foundation in physical organic chemistry, is required
- Knowledge of bioinformatics and structural biology (in particular how organic molecules interact with pockets on proteins or other biomolecules)
- Practical, working experience with computational chemistry software
- Ph.D. or equivalent in Chemistry, Chemical Biology, Biochemistry, Biophysics, or related discipline.
- Strong analytic capabilities with a strong understanding and experience using free energy perturbation calculations
- Strong comprehension of all aspects of modern drug discovery including medicinal chemistry, multi-parameter optimization, DMPK principles, etc.
- Ability to influence work in a highly entrepreneurial environment, and comfort with ambiguity
- Demonstrated interest and passion in entrepreneurship, startups, innovation, and/or healthcare
- Excellent communication, organization, and interpersonal skills
- Strong analytic capabilities and experience with a variety of analytic techniques
- Sees projects through to completion with the ability to meet deadlines
- Adept in taking direction and actively soliciting feedback
- Thrives under pressure with the capacity to handle and balance conflicting requests
- Acute attention to accuracy and detail in all aspects of responsibilities
- Highly proficient in Microsoft suite of programs
-
MD Anderson Cancer Center Houston, United States Full timeThis Institute Principal Research Scientist (Medicinal Chemistry) will lead cross-functional research to discover lead molecules for progression into novel oncology therapeutic agents that benefit patients. They will be a highly creative synthetic chemist with a strong desire to ...
-
Sales Manager
3 weeks ago
Management Recruiters International Houston, United StatesLarge North American raw material specialty chemical company is looking to fill a critical Sales Manager position, based ideally in the Dallas, Houston, or Atlanta areas. This is an excellent opportunity to join a growing and entrepreneurial company. It's also a solid income and ...
-
Chemist
1 day ago
Occidental Petroleum Corporation Houston, United StatesOxy is an international energy company with assets primarily in the United States, the Middle East and North Africa. We are one of the largest oil and gas producers in the U.S., including a leading producer in the Permian and DJ basins, and offshore Chemist, Chemistry, Producer, ...
-
Chemist
2 weeks ago
Occidental Petroleum Houston, United StatesTitle: Chemist · Location: United States-Texas-Houston · Other Locations: · *Description* · Oxy is an international energy company with assets primarily in the United States, the Middle East and North Africa. We are one of the largest oil and gas producers in the U.S., including ...
-
AAAS Houston, United States OTHERThis Institute Principal Research Scientist (Medicinal Chemistry) will lead cross-functional research to discover lead molecules for progression into novel oncology therapeutic agents that benefit patients. They will be a highly creative synthetic chemist with a strong desire to ...
-
Chemist
2 weeks ago
Occidental Petroleum Corporation Houston, United StatesOxy is an international energy company with assets primarily in the United States, the Middle East and North Africa. We are one of the largest oil and gas producers in the U.S., including a leading producer in the Permian and DJ basins, and offshore Gulf of Mexico. Our midstream ...
-
Postdoctoral Fellow
4 weeks ago
MD Anderson Cancer Center Houston, United StatesThe post-doctoral fellow will be embedded within the Structural Chemistry group in the Therapeutics Discovery Division. The position is designed to provide the experience needed to operate as a key member of a drug discovery project team at the program's conclusion. The fellow wi ...
-
Analytical Chemist I
2 weeks ago
Eagle Houston, United StatesWhat You Will DoPerform routing testing on samples under the supervision of a Project Chemist and/or Supervisor, i.e. track and meet testing deadlines, problem solve with team, notify supervisor of problems or unexpected results, record results · Maintain clean, orderly and safe ...
-
MD Anderson Cancer Center Houston, United StatesThis Institute Principal Research Scientist (Medicinal Chemistry) will lead cross-functional research to discover lead molecules for progression into novel oncology therapeutic agents that benefit patients. They will be a highly creative synthetic chemist with a strong desire to ...
-
University of Texas M.D. Anderson Houston, United StatesThis Institute Principal Research Scientist (Medicinal Chemistry) will lead cross-functional research to discover lead molecules for progression into novel oncology therapeutic agents that benefit patients. They will be a highly creative synthetic chemist with a strong desire to ...
-
Project Chemist
3 days ago
Eagle KMC Transportation Houston, United StatesWhat We're Looking For · The Project Chemist is responsible for supporting and leading multiple projects in operations and the R&D departments. · What You Will Do · •Performs development and validation of analytical methods and qualitatively /quantitatively testing routine and ...
-
Sales Manager
2 weeks ago
MRINetwork Jobs Houston, United StatesJob Description · Job DescriptionLarge North American raw material specialty chemical company is looking to fill a critical Sales Manager position, based ideally in the Dallas, Houston, or Atlanta areas. This is an excellent opportunity to join a growing and entrepreneurial compa ...
-
Pharmacy Technician at
2 weeks ago
The Chemist Pharmacy Sugar Land, United StatesJob Description · Job DescriptionThe Chemist Pharmacy in Sugar Land, TX is looking for one Pharmacy Technician our team · Job Summary: · A Pharmacy Technician assists pharmacists in dispensing medications, managing inventory, and providing excellent customer service. This role ...
-
R&D Chemist
2 weeks ago
Channel Personnel Services Houston, United StatesJob Description · Job Description · DUTIES / RESPONSIBILITIESØ Formulate and synthesis innovative hydrogen sulfide (H2S) scavengers for oil and gas applications, waste-water treatment, downstream refineries, and other H2S treating applications .Ø Establish projects to support the ...
-
Sales Manager
2 weeks ago
Management Recruiters International Houston, United StatesLarge North American raw material specialty chemical company is looking to fill a critical Sales Manager position, based ideally in the Dallas, Houston, or Atlanta areas. This is an excellent opportunity to join a growing and entrepreneurial company. It's also a solid income and ...
-
Analytical Chemist II
6 days ago
Eagle KMC Transportation Houston, United StatesWHAT YOU WILL DO · Performs routing testing on samples in a timely manner under the limited supervision of a Project Chemist and/or supervisor; tracks and meets assigned testing deadlines; notifies supervisor of problems meeting scheduled testing deadlines; records results in co ...
-
Auditor II- Product Certification
3 weeks ago
NSF Houston, United StatesJob Description · Description As Safety Specialist II Product Certification in Houston, TX, you will be responsible for providing audit services to certification programs and other NSF clients. Must have experience in cosmetics, dietary supplements or OTC drugs. · Responsibilit ...
-
Auditor II- Product Certification
3 weeks ago
NSF Houston, United StatesJob Description · As the Auditor Product Certification - Houston, TX, you will be responsible for providing audit services to Certification programs and other NSF clients. Those audits will include chemical companies, food equipment manufacturers, drinking water treatment units ...
-
Institute Research Investigator
2 weeks ago
EcoMap Technologies, Inc Houston, United StatesAdditional Information is for members only. Join now to get access · Share · Save to List · Sign in to save items, create lists to share with others, and unlock other features - all for free · Sign up or log in · Works at MD Anderson Cancer Center Houston Texas · Summary Pa ...
-
University of Texas MD Anderson Cancer Center Houston, United StatesWithin The University of Texas MD Anderson Cancer Center lies a powerful engine driving the future of new targeted, immune- and cell-based therapies: the Therapeutics Discovery Division. Therapeutics Discovery eliminates the bottlenecks that hamper traditional drug discovery, wit ...
Computational Chemist - Houston, United States - Texas Medical Center
Description
Job Description
Job DescriptionTHE ORGANIZATION
TMC Innovation (TMCi) is a flagship initiative of Texas Medical Center (TMC) that acts as a gateway to the facilities, resources, and network of the world's largest medical center. TMC Innovation includes TMCi Accelerator for health technologies, TMCi Accelerator for cancer therapeutics, TMCi Biodesign, TMCi Coworking spaces, and our resident corporate partnerships with Johnson & Johnson Innovation and ABB Robotics for Healthcare.
Designed to provide a comprehensive suite of services, TMC Innovation includes programming to meet the needs of disruptive healthcare startups at every stage, from ideation to commercialization.
TMC ACT
The Texas Medical Center (TMC), in collaboration with the Gulf Coast Consortia for Quantitative Biomedical Sciences (GCC) and The University of Texas Medical Branch at Galveston (UTMB), was selected for a $5M grant from The Cancer Prevention and Research Institute of Texas (CPRIT) for a cancer therapeutics program. This accelerator is specifically designed for individuals, or early-stage startups, that are focused on developing novel cancer therapeutics.
The program, called TMC ACT (Accelerating Cancer Therapeutics), is a comprehensive nine-month program designed to enhance biotech entrepreneurship training and comprehensive drug development programs in Texas. It will simultaneously provide Texas researchers and startup companies with integrated training, resources, and mentoring in order to help advance innovative cancer therapy discoveries into clinical trials, ultimately leading to new approaches and therapies to treat and/or cure cancer patients.
This program was built upon the successful TMC Innovation Healthtech Accelerator, the Gulf Coast Consortia's (GCC) network of Texas cancer researchers and research cores, and an experienced mentor community.
POSITION OVERVIEW
TMC Innovation is currently seeking a PhD-level researcher experienced in applying computational chemistry approaches to multi-parameter lead optimization. The Computational Chemist will assist investigators and project leaders, as needed, to provide advanced computational chemistry lead optimization resources to derisk drug discoveries and increase the likelihood of advancing them to clinical trials. TMC ACT is designed for individuals or early-stage startups that are focused on developing novel cancer therapeutics. This comprehensive nine-month accelerator program is focused on enhancing biotech entrepreneurship training and accelerating the participating companies' progression to their next major milestone.
The Chemist will work with participating companies and potential future program candidates, helping them navigate the path of drug development to be positioned for success. The Chemist will be expected to engage with numerous projects at varying stages and areas of clinical focus.
Ideal candidates exhibit the following qualities:
DUTIES AND RESPONSIBILITIES
KEY SELECTION AND SUCCESS FACTORS
Work Experience:
Education/Qualifications:
Texas Medical Center is an Equal Opportunity Employer. All applicants will receive consideration without regard to race, color, age, religion, gender, national origin, disability or Veteran status. If you require assistance or reasonable accommodation in the application process, please contact Human Resources at or