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    Senior Scientist I - East Irvine, United States - AbbVie

    AbbVie
    AbbVie East Irvine, United States

    Found in: beBee S2 US - 2 weeks ago

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    Full time
    Description

    Company Description

    At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit Follow Allergan Aesthetics on LinkedIn.
    Job Description

    We are seeking a self-motivated, discovery-oriented research scientist with a proven track record in conducting mass spectrometry-based protein characterization studies. The Senior Scientist I is responsible for developing and implementing analytical methods for the characterization of proteins and peptides with an emphasis on LC-MS (intact mass and peptide mapping). Expertise in data collection and data analysis software for these assays is a requirement. Proteomics and pull-down assay experience is desirable. Additional experience with analytical and separation techniques such as capillary electrophoresis (CE-SDS, cIEF) is beneficial.He/She/They will be expected to independently collect and interpret detailed MS data, generate reports, and orally present findings within team-basedsettings. He/She/They will provide scientific leadership as a subject matter expert and provide feedback and guidance to a team of protein expression/purification, cell-based, and in vivo scientists.The Senior Scientist I will independently plan experimental work and execute protocols in support of group goals depending on departmental needs. He/She/They will maintain a productive and collaborative laboratory environment consistent with group and company expectations.

    The position requires the individual to work with and in areas requiring select agents and toxins access (i.e. Biosafety level 2 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, the candidate must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements. AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements, and objectives.

    Responsibilities:

  • Execute the development of analytical methods for the characterization of biopharmaceuticals with an emphasis on LC-MS and biophysical characterization.

  • Apply routine and specialized analytical techniques to characterize and quantify biopharmaceuticals. Maintain reagent supplies, instrument maintenance schedules, notebooks, summarizes results in written reports and communicate observations to ensure that colleagues receive data and guidance in a timely manner. Comply with Quality Principals related to data generation and reporting.

  • Actively participate on cross-functional teams and provide support to other groups and external departments. Openly share scientific expertise and collaboratively help the team to formulate rational solutions to problems.

  • Develop protocols, train staff, and maintain the laboratory consistent with departmental and company requirements.

  • Maintain a good and current knowledge of the scientific and technical literature pertinent to the project and necessary for development of state-of-the-art analytical methods, including the acquisition of necessary equipment.

    Qualifications
    Qualifications:
  • Bachelors Degree or equivalent education and typically 10 years of experience. Masters Degree or equivalent education and typically 8 years of experience. Ph.D. and no experience necessary.
  • Extensive experience with the application of mass spectrometric, separation, and biophysical techniques for the characterization of proteins and their degradation and modification products. Expert-level experience with SYNAPT systems for intact MS and Orbitrap-based systems for bottom up peptide mapping techniques is a requirement.
  • Highly proficient in using data analysis software such as BioPharma Finder or Protein Metrics.
  • A strong understanding of methods and procedures related to the production and characterization of biopharmaceuticals is expected.
  • Strong analytical and instrument skills and a thorough understanding and working knowledge of analytical method development. Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law
    Additional Information
    AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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