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    Associate Director/Director - San Diego, United States - BioPhase

    BioPhase
    BioPhase San Diego, United States

    2 weeks ago

    Default job background
    Pharmaceutical / Bio-tech
    Description

    We seek an enthusiastic and highly motivated DMPK Lead to join our seasoned drug discovery and early development team. You will collaborate closely with the DMPK, biology, and chemistry teams to advance early discovery research programs into early clinical development, providing scientific and technical expertise.

    Key Qualifications

    • Extensive experience in a multifunctional DMPK group
    • Deep understanding of various DMPK assays and their application in solving project challenges
    • Proven ability to represent DMPK on multiple project teams
    • Strong mentorship and training skills for junior DMPK team members
    • Leadership experience in a pharmaceutical company
    • Excellent organizational and reporting skills
    • Proficiency in managing in-vivo and in-vitro ADME/PK studies
    • Experience in writing/reviewing nonclinical sections of regulatory submissions
    • Experience in contracting and managing CROs for nonclinical studies

    Requirements

    • Doctoral or Master's degree in analytical chemistry, biochemistry, or equivalent with relevant industry experience of 10+ or 15+ years.
    • Demonstrated ability to work independently in a fast-paced environment and a team setting.
    • Strong ability to manage multiple studies and DMPK activities simultaneously and assist in troubleshooting when instrument or assay problems arise.
    • Collaborate with medicinal chemists to design drug candidates that avoid metabolic liabilities and evaluate and select drug candidates based on potency in the biological target, overall ADME profile, and drug-drug interaction liabilities.
    • Manage and motivate in-house DMPK team player with a can-do attitude and good interpersonal skills.
    • Evaluate and interpret in vitro and in vivo DMPK data and liaise with DMPK colleagues to design studies to address critical project issues.
    • Prepare DMPK documents to support development candidate nominations and regulatory filings.
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