Senior Scientist Biomarkers - Maryland, United States - Io Biotech Inc.

Description

Do you want to contribute to the advancement of clinical biomarker assays at IO Biotech? We are seeking a highly motivated Sr.

Scientist to join our Research and Development team in Rockville, Maryland.

Under the guidance of senior personnel, you will play a pivotal role in designing and conducting R&D activities aimed at feasibility, optimization, and qualification of critical clinical biomarker assays.

This hands-on role will include assay development as well as analysis of clinical trial specimens.

The position offers an excellent opportunity for a highly talented and energetic scientist to contribute to a growing pipeline of assets in clinical development in an exciting and highly dynamic environment focused on developing cutting-edge immunomodulatory cancer therapeutics.

The future Sr. Scientist will be based in IO Biotech's established state-of-the-art US laboratories in Rockville, Maryland.

Key responsibilities include, but not limited to:

• Design and conduct R&D into feasibility, optimization, and qualification of clinical biomarker assays
• Perform hands on studies including ELISpot, tissue-based assays (e.g. IHC) and molecular studies including protocol development, assay optimization, qualification, and troubleshooting, and monitoring assay performance
• Conduct studies on clinical biospecimens for one or more clinical trials
• Analyze and interpret results, conduct meta-analyses, and apply statistical methodologies,
• Accessioning and recording clinical trial specimens according to established SOPs
• Serve as in-house subject matter expert on selected biomarkers
• Contribute to corporate biomarker team goals and collaborate with Clinical Operations, Data Science and Preclinical as needed.
• Prepare technical reports, summaries, presentations and communicate results
• Maintains appropriate workstation inventory, as well as current, complete, legible electronic/paper notebooks and laboratory records in compliance with good scientific and regulatory practices
• Assist with general lab duties, protocols and compliance responsibilities, and be proactively involved in assigned research

To be successful in this role, you have:

• A PhD in immunology, cell biology or related field, plus two years experience (or Master's plus four years experience)
• Strong written and verbal communication
• Excellent cross-functional team participation skills
• Proven skills in assay development and data analytics
• Hands-on experience with primary human immune cells assays and molecular techniques
• Familiarity with tissue biology-based techniques such as immunohistochemistry or immunofluorescence
• Experience organizing, managing, and analyzing scientific data sets and proficiency with MS Excel, PowerBI, or SQL
• Self-motivated, detailed-oriented, proactive, and organized
• Able to prioritize and manage multiple projects simultaneously in a dynamic environment to meet deadlines

Preferred additional experience & skills:

• Two or more years of industry experience
• Demonstrated understanding and hands-on experience with in vitro models and cancer biology
• Prior experience in assay development in tissue/cell-based assays such as immunohistochemistry (IHC), fluorescent microscopy, pathology imaging, and analysis
• Experience in operating and maintaining IHC equipment such as autostainers, scanners, etc.
• Experience in R, Python, or other programming languages desirable
• Generation and management of relational databases for analysis of data or publication of interactive dashboards
• Bioinformatics experience helpful

What we offer:

• The possibility to join a lean organization where contributions have an immediate impact and is acknowledged.
• A global work environment
• An informal working culture with room to bring ideas and initiatives to life.
• Competitive salary and benefit package

Interviews may be conducted on an ongoing basis.

We look forward to receiving your application

IO Biotech is a clinical-stage biopharmaceutical company pioneering the first-in-class investigational dual-action immune-modulating cancer vaccine with the goal of becoming the backbone of combination therapy for people with cancer.

The Company's T-win vaccine platform is directed against the tumor microenvironment (TME) and is designed to stimulate T cells against tumor cells and the most important immune-suppressive cells in the TME.

IO Biotech's most advanced program for IO102-IO103 is currently in Phase 3 development.

If you have any questions, please contact

Amy Wesa

VP Biomarkers

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Application deadline: 31. May 2024