- Analyze clinical histopathology images using digital pathology to identify features predictive of patient outcomes/clinical response to an oncology therapeutic.
- Develop digital image analysis algorithms using traditional and AI-based technology to extract quantitative feature data from histology stains (H&E) and validated IHC assays.
- Provide digital pathology support to enable integrated translational strategies, including patient selection, pharmacodynamics, mechanism of action/resistance, prognostic, and other clinically relevant biomarker applications.
- Oversee the execution of histopathology strategies and deliver biomarker results to internal and external stakeholders while working collaboratively with Translational Biomarker Leads, Biology, Clinical Science, Biometrics, Bioinformatics, Clinical/Biomarker Operations, and others. Including CDx activities as applicable.
- Serve as histology/IHC subject matter expert in collaborative cross-functional biomarker teams providing expertise, driving decisions as well as enabling execution of tissue-based biomarker plans.
- Present IHC biomarker data at project teams, review forums, and to external groups
- Responsible for authoring the tissue biomarker sections of clinical protocols and regulatory documents.
- Using advanced digital image analysis software and spatial imaging platforms (AI-based tissue analysis, software such as Indica Labs HALO, Visiopharm, QuPath/ImageJ, digital slide scanning, multiplex spectral imaging, Akoya Opal systems including Polaris/PhenoImagerHT)
- Strong background in translational research in preclinical and clinical settings, including analyzing histology samples for predictive value in oncology studies
- Experience developing histological biomarker assays across a broad range of platform technologies (e.g. IHC, mIF, ISH, FISH, special stains) and their clinical application
- Strong verbal and written communication skills and experience presenting complex datasets to a variety of audiences (clinical and pre-clinical discovery scientists)
- Experience in drug development and leading teams, at least 2 direct reports
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Associate Director Digital Pathology
2 weeks ago
Arcus Biosciences, Inc. Hayward, United StatesAssociate Director - Digital Pathology / Translational Science · Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We are an oncology-focused biopharmaceutical company leveraging its deep cross-discipline expertise t ...
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Associate Director Digital Pathology
1 week ago
Arcus Biosciences Hayward, United StatesAssociate Director – Digital Pathology / Translational Science · Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We are an oncology-focused biopharmaceutical company leveraging its deep cross-discipline expertise t ...
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F. Hoffmann-La Roche AG Santa Clara, United StatesYou will define system requirements for Digital Pathology software (including software programs and applications, user interface software and/or software algorithms) and instrumentation projects, and prepare written specifications according to standa Systems Engineer, Software, P ...
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Senior Digital Pathology Sales Specialist
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Ascensia Diabetes Care Holdings AG San Francisco, United StatesAscensia Diabetes Care is a global specialist diabetes care company, dedicated to helping people living with diabetes. Our mission is to empower people living with diabetes through innovative solutions that simplify and improve their lives. We use our innovation and specialist ex ...
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Staff Pathologist
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Guardant Health Redwood City, United States Full timeJob Description · The Staff Pathologist is responsible for ensuring delivery of quality clinical laboratory services and products within Guardant's Oncology Division. This position will serve as an associate director in a team of pathologists and laboratory directors. Specific ...
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Soliant Oakland, United States Full timeMinimum 1+ years speech therapy experience required. · Join Our Team: Full-Time Virtual or Onsite Speech Language Pathologist (SLP) in Oakland, CA · We are looking for a dynamic Speech Language Pathologist to join our team, with the flexibility to work either virtually or onsite ...
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Research Associate
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Innova Solutions San Mateo, United States ContractInnova Solutions is immediately hiring a Research Associate III/Histology Technician IV · Position type: Full-time Contract · Duration: 12 months and possibility for extension · Location: Foster City, CA · As a Research Associate III/Histology Technician IV you will: · MORE INFO ...
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Genomic Health, Inc. Redwood City, United States Full timePosition Overview · The Lead Engineer, Process Development and Automation leads, manages, implements, and provides technical engineering support for a variety of process automation hardware, software applications, and laboratory instruments. This position works and collaborates c ...
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Senior Science Writer/Editor
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Agilent San Francisco, United States Full timeDescription · A talented and experienced Senior Science Writer/Editor who will be part of the Agilent Writing Center of Excellence, is required to write and copyedit science marketing content. The role entails writing, editing, and proofreading a variety of digital marketing web ...
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Postdoctoral Fellow
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Stanford University Stanford, United StatesA machine learning-focused postdoctoral scholar position is available at the Stanford University School of Medicine. No prior life science experience is necessary. The scholar will join a machine learning group with unparalleled direct access to clinical resources, as well as Sta ...
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Senior Research Associate, PAS
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Bio-Techne Newark, United StatesJob Details · Level: Experienced · Job Location: Newark CA - Newark, CA · Position Type: Full Time · Education Level: Bachelor's Degree · Salary Range: Undisclosed · Travel Percentage: Up to 10% · Job Shift: Day · Job Category: Research · Description · By joining Bio-Techne, you' ...
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Research Associate II
3 weeks ago
R&D Partners Foster City, United StatesJob Description · Job DescriptionBiotechnology company is hiring a Research Associate II within the Pathobiology department to contribute to histology and pathology workflows in support of pre-clinical in vivo pharmacology studies. This position will support drug development in d ...
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Research Associate
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Intelliswift Foster City, United StatesResearch Associate - II* Job ID: · Job Title: Research Associate II, Pathobiology · Location: Foster City, CA · Duration: 18 months assignment · The In Vivo Pathology (IVP) team within the Pathobiology department is seeking a research associate to contribute to histology and pat ...
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Senior User Interface Engineer
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Ramp Talent West Valley City, United StatesAbout the job · Our Client, Pathology Watch, is seeking a Senior UI Engineer to join the team and help them with web application development. · Key Technology stack: React, TypeScript, CSS · More Details below... · Pathology Watch is building a system that makes pathology (ca ...
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Telehealth Speech Pathologist
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Sunbelt Staffing Palo Alto, United StatesJob Description · Job DescriptionMinimum 1+ years speech therapy experience required. · Exciting Opportunity for Speech-Language Pathologist (SLP) in California · Are you a licensed Speech-Language Pathologist (SLP) seeking a fulfilling role in California? Join our team for the 2 ...
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Virtual California Speech Language Pathologist
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Sunbelt Staffing Oakland, United StatesJob Description · Job DescriptionMinimum 1+ years speech therapy experience required. · We are collaborating with a school district in California to fulfill a teletherapy Speech Language Pathologist role · This position is fully remote, and we are actively arranging interviews · ...
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Virtual Speech Language Pathologist
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VocoVision San Francisco, United StatesJob Description · Job DescriptionMinimum 1+ years speech therapy experience required. · VocoVision is urgently seeking a licensed Speech-Language Pathologist (SLP) in California This opportunity extends through the culmination of the 2023/2024 school year, with a strong likelihoo ...
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Scientist - Pathology
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Amgen South San Francisco, United States**HOW MIGHT YOU DEFY IMAGINATION?** · You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission-to serve patients ...
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VocoVision San Francisco, United StatesJob Description · Job DescriptionMinimum 1+ years speech therapy experience required. · Job Description: · Seeking a rewarding role in California where you can support students from the comfort of your own home? Come join us at VocoVision Our tele therapists thrive in a fully rem ...
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Scientist - Pathology
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BioSpace South San Francisco, United StatesJob Details · HOW MIGHT YOU DEFY IMAGINATION? · Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve ...
Associate Director Digital Pathology - Hayward, United States - Arcus Biosciences
Description
Associate Director - Digital Pathology / Translational ScienceArcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies.
We are an oncology-focused biopharmaceutical company leveraging its deep cross-discipline expertise to discover highly differentiated therapies and develop a broad portfolio of novel combinations addressing significant unmet needs.
Overall description:We have an opening for an Associate Director (AD) with expertise in the field of digital pathology.
The AD will be responsible for the development, execution, and oversight of AI-based digital image analysis on clinical histopathology images and integrating these analyses into comprehensive biomarker plans for assets in oncology clinical development.
The ideal candidate will have experience successfully developing and applying digital image analysis algorithms that are predictive of clinical response to a therapeutic agent, ideally in the field of oncology.
The role requires demonstrated expertise in histopathology, microscopy, tissue-based assay development (IHC/ISH/mIF), analysis, and data interpretation with an ability to integrate scientific and disease specific contexts.
The successful candidate will have a well-established track record of using digital image analysis and must have experience working with CROs to implement IHC assays suitable for downstream digital analysis.
The ideal applicant should also have experience working with pathologists to develop appropriate scoring methods, and familiarity with multiplex chromogenic and fluorescent IHC assays and quantification methodology.
Strong communication and leadership skills are required to build relationships with key stakeholders bridging research and clinical development.The AD will be required to present data regularly at project team meetings to inform key leadership decisions.
This position demands unwavering attention to detail and strong organizational skills, coupled with aptitude and enthusiasm for collaborating, maintaining high quality data, and managing the integrity of our clinical trial datasets and sample records.
Supervisory and mentoring experience is also required to manage more junior staff members to ensure technical specifications are carried out appropriately and meet project timelines.
Excellent oral and written communication skills are required, along with a solutions-based approach, flexibility, and the ability to focus and deliver on time-sensitive objectives.
Job duties and responsibilities include, but are not limited to:D. or M.D.
in a relevant scientific field such as pathology, histology, immuno-oncology, oncology, or immunology, with experience in relevant life sciences disciplines and at least 10 years of experience, including significant time in industry, or a Masters Degree with 15 years of experience, in addition to:
Factors such as relevant experience, education, duration of experience, and length of industry experience will influence the actual title and salary offered.
In addition to a competitive market-based salary, Arcus offers the opportunity to participate in stock programs, a performance-based bonus, and a comprehensive benefits package.
Additional information about our total rewards program can be found here:.
Arcus Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind.
Arcus is committed to the principle of equal employment opportunity for all employees and does not discriminate based on race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status.
EOE/AA/Vets.#LI-KT1
Associate Director Digital Pathology professionals in Hayward
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Grace Hill
Regulatory Consultant (Veeva RIM)