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    R&D Chemist - Indianapolis, United States - CBRE

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    Description
    R&D Chemist (Process Crystallizaton)

    Job ID

    160637

    Posted

    26-Mar-2024

    Service line

    GWS Segment

    Role type

    Full-time

    Areas of Interest

    Engineering/Maintenance, Research

    Location(s)

    Indianapolis - Indiana - United States of America


    Full Spectrum Lab Services from CBRE offers a professional suite of services to a variety of clients in the life sciences industry, including those in pharmaceuticals, biotech, medical devices, and genomics, as well as contract research organizations (CROs) and contract manufacturing organizations (CMOs).


    Our comprehensive range of services includes laboratory consulting, real estate services, instrumentation repair and maintenance, full asset management, and more-covering the entire spectrum of life sciences facilities.

    With expertise across various life sciences categories, CBRE is a leader in managing highly-regulated spaces within the industry.


    About the role


    As a laboratory scientist in the SMDD biosynthetic drug substance development group, you will help with solubility and chromatography work related to process crystallization.


    This position is for an experienced chemist possessing in depth technical knowledge to perform multiple laboratory functions and various types of laboratory analysis.

    Instrument integration with automated data analysis workflows and process sampling interfaces.

    A strong scientific or chemical engineering foundation is a prerequisite for this role. In addition, the ability to exhibit a high level of attention to detail and good record keeping is essential.

    Maintaining accurate records and interpreting data to provide detailed information and analysis on the execution of experiments will be a daily activity.


    Location:
    This is an onsite position based on a pharmaceutical client's site in Indianapolis, IN.


    What you'll do

    • The laboratory chemists will support the solubility and chromatography work related to process crystallization
    • Conduct routine analyses in compliance with applicable methods, protocols, SOPs, and regulatory agency guidelines.
    • Analytical support and Method development of both quantitative and qualitative HPLC methods
    • Preparative HPLC purification/isolation of process impurities and degradation products
    • Analytical instrument maintenance:
    Support minor instrument repairs, setup, software troubleshooting, and/or routine maintenance of LC and UPLC/MS equipment and preparation of laboratory reagents


    • Data analytics:
    Operation of a variety of instrumentation to generate comprehensive and high-quality analytical results.


    • Instrumentation may include:

    Liquid handling systems, HPLC, UPLC, Mass spectrometers, Microscopy, Thermal Properties (DSC), Thermal Gravimetric Analysis (TGA), Hygroscopicity (VTI), Karl Fisher, and XRPD, powder doser, EasyMax instrument and software, and crystal16 instrument and software.


    • AKTA automated liquid chromatography for purification of proteins and peptides.
    • AKTA Unicorn, Waters Empower and electronic notebooks.
    • Fluorescence Spectroscopy
    • LC-MS analysis in support of synthetic molecule development and interpretation of results.
    • Ensure project deliverables are scientifically accurate and meet timeline expectations.
    • Comply with all laboratory Safety guidelines including Personal Protective Equipment (PPEs).
    • Maintain general cleanliness of the lab, including personal bench space and common-use areas, and maintain laboratory supplies.
    • Participates in required training activities.
    • Perform method analysis and development with quick turnaround times.

    What you'll need

    • Bachelors or Masters in Biochemistry, Chemical Engineering or related degree with at least 2 years of proven experience in laboratory techniques and development.
    • Applicants must be currently authorized to work in the United States without the need for visa sponsorship now or in the future

    Skills / Preferences:

    • Solubility and chromatography work related to process crystallization
    • Effective interpersonal, oral and written communication skills with a clear understanding of good documentation practices.
    • Strong laboratory skills and basic analytical skills and understanding.
    • Purification development experience.
    • Experience with process control and documentation systems (AKTA Unicorn, Waters Empower analytical software, electronic notebooks)

    Why CBRE?
    We offer comprehensive benefits such as health, vision and life insurance, 401k, personal time off, among others.


    Equal Employment Opportunity: CBRE is an equal opportunity employer that values diversity. We have a long-standing commitment to providing equal employment opportunity to all qualified applicants regardless of race, color, religion, national origin, sex, sexual orientation, gender identity, pregnancy, age, citizenship, marital status, disability, veteran status, political belief, or any other basis protected by applicable law.


    Candidate Accommodations: CBRE values the differences of all current and prospective employees and recognizes how every employee contributes to our company's success. CBRE provides reasonable accommodations in job application procedures for individuals with disabilities. If you require assistance due to a disability in the application or recruitment process, please submit a request via email at or via telephone at U.S.) and Canada).


    NOTE: Some, but not all, of our positions may have an additional requirement to comply with COVID-19 health and safety protocols, including COVID-19 vaccination proof and/or rigorous testing. If you have questions about the requirement(s) for this position, please inform your Recruiter.

    CBRE, Inc. is an Equal Opportunity and Affirmative Action Employer (Women/Minorities/Persons with Disabilities/US Veterans)

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