Associate Director/Director, Research - Chicago, United States - Tempus

Description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way.

Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for an Associate Director of R&D to support the development of new assays and processes for deployment in our clinical lab related to Tempus's liquid biopsy portfolio in oncology.

This role involves leading a team towards the execution of advanced molecular techniques toward the development of the most advanced sequencing platform in cancer care.

What You'll Do:
Lead a development and validation team from project inception through launchincluding sample selection, hands-on laboratory validation, establishing workflowand SOPs, and authoring validation plans and summaries

Ensure activities are consistent with project critical path and respondappropriately to changing priorities

Facilitate smooth transfers of developed workflows into clinical lab environments

Evaluate emerging molecular and sequencing technologies and align these to business initiatives and product portfolio needs

Mentor scientific staff on experimental design, continuous learning, and time management

Conduct troubleshooting and quality control initiatives

Assist with the development of automated processes

Provide flexible support for other activities in the clinical Next Generation

Sequencing lab, including emerging technology assessment, LIMS consulting,instrument troubleshooting, etc.


Qualifications:
Master's degree with 10+ years experience or Ph.
D. with 5+ years experience inmolecular techniques

Strong analytical and conceptual capabilities, interpersonal skills, and ability tocommunicate with clarity

Highly organized and systematic, superb attention to detail, and ability to complete tasks with a high degree of accuracy

Track record of assay and/or product development

Hands-on experience with any of the following molecular methods is highly desired:

NGS library preparation methods

Knowledge of liquid biopsy in oncology space

PCR methods such as:
PCR, qPCR, RT-PCR, ddPCR

Nucleic acid ligations

Nucleic acid analysis such as:
quantitation by absorbance/fluorescence, gel & capillary electrophoresis

Magnetic bead-based DNA/RNA purification and size selection


MLPA
Sanger Sequencing

DNA hybridization arrays


Highly Desirable:
Thrives in a fast-paced environment

Experience with robotics and automated liquid handling systems

Experience in validation of clinical assay validation

Knowledge of LIMS platforms and various computer systems

Experience developing and validating assays according to various US andinternational regulatory body requirements

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