Senior Scientist, Analytical Development - South San Francisco, CA, United States - Cellares

Description

South San Francisco, CAProcess Sciences – Analytical Development /Full Time /On-sitePosition SummaryWe are seeking an innovative, creative, and detail-oriented Scientist/Senior Scientist to join our team in South San Francisco.

This position will work with the Director of Analytical Development to develop flow cytometry-based assays for cell therapy products from various platforms.

Our ideal candidate is a self-motivated individual with a passion for improving current manufacturing practices for cell therapies and extensive experience in multi-color flow cytometry assays.

This is a multidisciplinary role & this individual will interface with clients and across many parts of the organization (with scientists, researchers, and engineers) to develop the best solutions possible.

The successful candidate will be well versed in analytical development, technology transfer, and training.

Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.

ResponsibilitiesLead method development, optimization and pre-qualification of flow cytometry protocols for the characterization of cell therapy productsProvide analytical support in assay transfer to cGMP QC laboratories and from clients to the analytical development teamPlan and perform multicolor flow cytometry experiments to support product development and optimization Analyze and interpret flow cytometry data using software like FCSExpress, FlowJoMaintain and troubleshoot flow cytometry instrumentsCollaborate with cross-functional teams to ensure effective communication and productive interactions with internal and external stakeholdersGuide and train associates in the team and serve as the subject matter expert on multicolor flow cytometryCollaborate with cross functional teams to develop core analytical testing capabilities for cell & gene therapy products using flow cytometry techniquesFile data and complete experiment report in a timely mannerPrepare test plans and analyze/summarize experimental data and present findings at both internal and external meetingsResponsibility to develop, author, review, and/or approve Standard Operating Procedures, specifications, regulatory filing, or other controlled documents as neededAssist with laboratory maintenance (cleaning, equipment maintenance, biohazard waste removal)

Directly drive user needs and requirements discussions for analytical methods, work closely with internal and external teams to translate user needs into actionable requirementsManage reagent and consumables inventory and ordering as neededRequirementsBachelor's, Master's, or PhD in Biochemistry, Molecular Biology, Biology or related subject with 6-21 years of analytical experience in the cell and gene therapy manufacturing fieldSubject Matter Expert in immune cell phenotyping by multicolor flow cytometry; including flow assay development, optimization, and tech transferProficiency in data analysis and interpretation using FCSExpress or FlowJoProficiency in the operation and troubleshooting of flow cytometry analyzers (Hands on experience with spectral flow cytometer is a plus)Ability to build strong partnerships and effectively integrate with external collaborators to drive projects/programs forward in a matrixed environmentExperience in writing Standard Operating Procedures (SOPs) and protocol documentationExperience with liquid handlers and automation is a plusExcellent written and oral communication skills to present findings and interact with key stakeholdersStrong background in cell biology, immunology, and molecular biologyStrong analytical, problem solving and critical thinking skills and the ability to lead as a change agent to promote flexibility, creativity, and accountabilityExcellent teamwork and interpersonal skills with ability to influence and build strong working relationships at all levels within the organizationMust be able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environmentSelf-motivated and passionate about advancing the field of cell therapiesPossess self-awareness, integrity, authenticity, and a growth mindsetAnnual Salary Range:
$90,000 - $210,000Cellares total compensation package contains competitive base salaries, highly subsidized Medical, Dental, and Vision Plans, 401(k) Matching, Free EV Charging, Onsite lunches, and Stock options. All displayed pay ranges are approximate, negotiable, and location dependent.

This is CellaresCellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century.

The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies.

The company's Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation.

Cell Shuttles will be deployed in Cellares' Smart Factories around the world to meet total patient demand for cell therapies at global scale.

Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.

The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.