- Utilize cloning techniques to generate DNA constructs, CRISPR-based tools, and viral vectors for research
- Develop assays to identify and evaluate recycling pathways and surface proteins in neurons
- Utilize microscopy and imaging to study the regulation of synaptic activity
- Conduct patch-clamp electrophysiology to probe the impact on synaptic function
- Provide guidance to lab members, contribute to manuscripts and grant applications, mentor junior researchers, and present work at scientific platforms
- Ph.D. in a biology-related field
- Minimum five years of postdoctoral experience in cell biology and neurosciences
- Experience in investigating endomembrane trafficking at synapses
- Experience supervising research activities of junior trainees
- Minimum 3 years of experience with patch-clamp electrophysiology
- Generous time off
- Retirement plan with matching contributions
- Comprehensive health insurance options
- Dental, Vision, and Legal Insurance
- Life insurance and disability coverage
- Flexible spending accounts for healthcare and dependent care
- Maternity and Parental Leave
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research investigator - Ann Arbor, United States - University of Michigan
Description
Position: Research Investigator at the Laboratory of Dr. Lois Weisman
The research team led by Dr. Weisman is seeking a Research Investigator to carry out and oversee investigations on Retromer- and Retriever-dependent receptor recycling at synaptic locations, focusing on pathways influenced by synaptic activity and phosphoinositide signaling lipids. You will utilize a range of techniques spanning biochemistry, cell biology, advanced microscopy, and patch-clamp electrophysiology to shed light on the regulation of these complexes at synapses, as well as identify the synaptic proteins involved in each pathway. Your work will provide valuable insights into endocytic recycling at postsynaptic sites, contributing to groundbreaking discoveries in the field.
The **Life Sciences Institute** embarks on a mission to explore biological processes on a global scale, showcasing a vibrant community of curious minds equipped with cutting-edge tools to facilitate breakthroughs.
Responsibilities:
Required Qualifications:
Desired Qualifications:
Benefits at the University of Michigan:
Background Screening:
All job candidates undergo background checks in compliance with regulations.
U-M EEO/AA Statement:
The University of Michigan upholds equal opportunity practices.