Research Associate I/II, LNP Formulations - Somerville, United States - Tessera Therapeutics

Description

Company Summary:

Tessera Therapeutics is pioneering Gene WritingTM- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

Position Summary:

The Research Associate will be responsible for developing LNP formulations and processes to support company's in vitro and in vivo pre-clinical studies. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.

Key Responsibilities:

• Strengthen Tessera's gene editing delivery platforms by formulating and developing novel LNPs
• Routinely formulate nucleic acid payloads to support company's in vitro and pre-clinical studies
• Utilize physicochemical testing methods to screen and characterize novel LNP formulations
• Maintain thorough and detailed electronic lab notebooks (ELNs) and documentation records
• Work both independently and as part of a team to adapt to changing priorities in a fast-paced environment
• Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering, and receiving of lab supplies
• Adhere to all laboratory safety requirements and procedures

Basic Qualifications:

• BS with up to 4 years of experience, or MS and up to 2 years of experience. Degrees in Chemistry, Chemical Engineering, Biomedical Engineering, Material Science, or closely related field is required.
• Prior experience in LNP delivery or formulations
• Strong communication and collaboration skills
• Highly organized and detail-oriented
• Prior experience with scientific and experimental documentation

Preferred Qualifications:

• Proven ability to work with a high level of integrity, accuracy, and attention to detail
• Strong organizational skills that enable a high level of productivity and timely completion of assignments
• Excellent oral and written communication skills for effectively interfacing with all members of the company
• Ability to excel in a dynamic, fast-paced, and highly collaborative environment
• Ability to troubleshoot process equipment and analytical instrumentation
• Deliver effectively on time sensitive assignments, and document/communicate scientific data
• Perform experiments that involve preparation and physiochemical characterization of nanoparticles
• Supply LNP test articles for biological studies
• Possess a strong work ethic and good documentation practices, including electronic laboratory notebook and inventory maintenance
• Perform duties according to applicable safety procedures
• Knowledge of nucleic acid chemistry and biology

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics' internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.