Jobs
>
Grand Rapids

    Research Associate-Fixed Term - Grand Rapids, United States - Michigan State University

    Default job background
    Description
    Job postings

    Research Associate-Fixed Term

    Back to search results Apply now Job no:


    Work type:
    Faculty/Academic Staff


    Major Administrative Unit / College:
    College Of Human Medicine


    Department:
    Pediatrics And Human Development


    Sub Area:
    FAS- Fac./Acad Staff


    Salary:
    Salary Commensurate with Experience


    Location:
    Grand Rapids


    Categories:
    Research/Scientific, Fixed Term Academic Staff, Full Time %), Non-Union

    Position Summary


    The Chen Lab with the Michigan State University Department of Pediatrics and Human Development is currently recruiting postdoctoral Research Associates to augment our research program.

    Conventional drug discovery is focused on finding agents that modulate one molecular feature, typically a protein target. This approach was adopted a few decades ago, even before the emergence of omics technologies.

    Today's technologies allow the profiling thousands of molecular features including proteins, mRNAs, and metabolites, all of which can contribute to disease development.

    Finding one magic bullet from these thousands of features is a daunting task. Moreover, focusing only on a single feature does not fully utilize all the information generated from new omics technologies.


    The Chen Lab has developed a systems approach that considers how drugs affect a disease gene expression signature, which is comprised of a set of up-/down-regulated disease genes.

    This approach has led to the discovery of therapeutic candidates for seven indications including hepatocellular carcinoma (Gastroenterology, 2017), melanoma (Molecular Pharmacology, 2022), Alzheimer's disease (Nature Aging, 2021), Diffuse intrinsic pontine glioma (Acta Neuropathologica Communications, 2022), and SARS-CoV-2 (iScience, Moreover, we have discovered that the potency to reverse gene expression correlates with drug efficacy, providing strong evidence of using this approach in drug repurposing (Nature Communications, We have developed a drug-repurposing platform called OCTAD (Nature Protocols, 2021), allowing researchers to predict repurposed drug candidates for cancers and cancer subtypes.

    Currently we are developing new AI approaches to support novel compound screening and lead optimization.

    Our recent conference papers demonstrated the feasibility through improving the training data quality (ICDM, 2020), pre-training graph neural network (KDD, 2021) and tree search based multi-objective optimization (KDD, 2022, Best Paper Award).

    We aim to design novel compounds that could control cell lineage development, modulate the microenvironment, and treat cancer and aging.

    Equal Employment Opportunity Statement


    All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.

    Required Degree

    Doctorate -Pharmacology or a related field

    Minimum Requirements

    Candidates must possess a terminal degree (PhD) in Pharmacology, Medicinal Chemistry, Chemical Biology, or a related field.

    Desired Qualifications

    Candidates with experience in computational drug screening and an interest in running an independent lab after training are preferred.

    Required Application Materials


    • Cover Letter
    • CV
    Review of Applications Begins On

    05/30/2023

    Website

    Department Statement


    Established in 1968 with the formation of the Michigan State University College of Human Medicine, the Department of Pediatrics and Human Development seeks to balance behavioral science, basic biological research, and clinical pediatrics into a comprehensive approach to the health and development of the child and the family.

    MSU Statement

    Michigan State University has been advancing the common good with uncommon will for more than 160 years.

    One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.


    Advertised:
    May 15, 2023 Eastern Daylight Time


  • Michigan State University Grand Rapids, United States

    Job postings · Research Associate-Fixed Term · Back to search results Apply now Job no: · Work type: Faculty/Academic Staff · Major Administrative Unit / College:College Of Human Medicine · Department:Family Medicine, Department Of · Sub Area:FAS- Fac./Acad Staff · Salary:Sala ...


  • Michigan State University Grand Rapids, United States

    Job postings · Research Associate-Fixed Term · Back to search results Apply now Job no: · Work type: Faculty/Academic Staff · Major Administrative Unit / College:College Of Human Medicine · Department:Family Medicine, Department Of · Sub Area:FAS- Fac./Acad Staff · Salary:Sala ...


  • Michigan State University Grand Rapids, United States

    Job postings · Research Associate-Fixed Term · Back to search results Apply now Job no: · Work type: Faculty/Academic Staff · Major Administrative Unit / College:College Of Human Medicine · Department:Pediatrics And Human Development · Sub Area:FAS- Fac./Acad Staff · Salary:Sa ...


  • Michigan State University Grand Rapids, United States

    The Chen Lab with the Michigan State University Department of Pediatrics and Human Development is currently recruiting postdoctoral Research Associates to augment our research program. Conventional drug discovery is focused on finding agents that mod Research Associate, Research, ...


  • Michigan State University Grand Rapids, United States

    The Michigan State University Social and Emotional Neurodevelopment (SEND) Laboratory explores the neurological underpinnings of neurodevelopmental disorders, particularly those in which disruptions to affect and reward can have detrimental effects. Research Associate, Associate, ...


  • Michigan State University Grand Rapids, United States

    The HELP PAIN Lab, directed by Natoshia R. Cunningham, PhD, at Michigan State University is recruiting one postdoctoral research associate in pediatric pain starting in summer/fall 2024. The start date is flexible and a two-year commitment is preferr Research Associate, Research, ...


  • Michigan State University(MSU) Grand Rapids, United States

    Working/Functional TitleAst Prof/Asc Prof/Prof Fixed TermPosition SummaryThe College of Human Medicine at Michigan State University invites applicants for the position of Learning Society Fellow to participate in the undergraduate medical education in the Shared Discovery Curricu ...


  • Extended Stay America Kent, United States Full time

    Requirements · KNOWLEDGE, SKILLS, ABILITIES & COMPETENCIES · Ability to communicate effectively with management and staff and comprehend instructions, short correspondence, and memos. · Ability to add, subtract, multiply, and divide in all units of measure, using whole numbers, ...


  • TJX Companies, Inc. Grand Rapids, United States

    Opportunity: Contribute To The Growth Of Your Career · Completes the daily tasks required for Store Loss Prevention and safety programs. Maintains positive relationships with Store Management. Conducts apprehensions within established policies and guidelines. Communicates with st ...


  • MSC Industrial Supply Grand Rapids, United States

    Build a better career with MSC. · Serving customer and community starts with the very best people doing their very best work. That is precisely what we have at MSC Industrial Supply Co., a leading North American distributor of metalworking and maintenance, repair, and operations ...


  • Parker Aerospace Kent, United States

    Parker Aerospace is a global leader in commercial and military aircraft and aeroengine technology. With the addition of Parker Meggitt, the company collaborates with customers to enable engineering breakthroughs that lead to a better tomorrow. · Are you ready to join an industry- ...

  • Sam's Club

    Meat Lead

    3 weeks ago


    Sam's Club Kentwood, United States Full time

    Position Summary... · As a Meat Department Lead you will drive sales in your area and supervise your team of hourly associates to deliver to our members more of what they love, for less. You will model expertise in Meat and work collaboratively with other team leaders to ensure ...


  • Rental Property Owners Association Grand Rapids, United States

    The Rental Property Owners Association of Kent County (RPOA) is a non-profit professional organization that represents more than 2,000 members of rental property owners both long and short term, real estate investors and vendors in the rental property industry. The RPOA provides ...


  • Beacon Hill Grand Rapids, United States

    Beacon Hill Legal is partnering with a top firm in Michigan, that is looking to add a Labor & Employment Associate to their growing practice group. This role can sit anywhere in Michigan, Grand Rapids is ideal. · The ideal candidate will have 2+ years of L&E experience in a soph ...

  • City of Grand Rapids

    Social Worker

    4 days ago


    City of Grand Rapids Grand Rapids, United States

    This position is responsible for professional social work at the police department in which support to members of the general public and police personnel is provided to those who require victim advocate and crisis intervention services. This includes delivering short-term intensi ...

  • Canteen

    food service utility

    2 weeks ago


    Canteen Kent, United States Full time

    Canteen We are hiring immediately for a full time FOOD SERVICE UTILITY position. · Location : MG Foods - 701 Monster Road SW, Renton, WA 98031 Note: online applications accepted only. · Schedule : Full time schedule. Days and hours may vary. Must be able to work weekends. More ...


  • BluePearl Grand Rapids, United States Full time

    If you are a current associate, you will need to apply through our internal career site. Please log into Workday and click on the Jobs Hub app or search for Browse Jobs. · BluePearl in Grand Rapids, MI is hiring a remarkable Veterinary Receptionist for our growing hospital. The ...

  • LocumJobsOnline

    Locum Physician

    1 week ago


    LocumJobsOnline Grand Rapids, United States Full time

    LocumJobsOnline is working with Weatherby Healthcare to find a qualified Obstetrics and Gynecology MD in Bad Axe, Michigan, 48413 · About The Position · Enjoy the locum tenens lifestyle knowing Weatherby is here to support you every step of the way. Call and speak to one of our c ...


  • Corewell Health Grand Rapids, United States

    Corewell Health is offering up to $10,000 as a sign on bonus for this opportunity · About the unit · With 2 floors and 164 beds we are able to provide care for long term care residents and post-acute rehab patients. Nurse-patient ratios vary depending on the shift and the populat ...


  • ATI Physical Therapy Grand Rapids, United States

    Overview: · Title: · Registered Nurse Occupational Health · Location: · Grand Rapids, MI · Status: · Full Time · Hours: · M-Th 7:00am-3:00pm; 30 hours per week · This role will provide case management services for an employer, · embedded within the clinic per contract agreement p ...